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A0JP82

- A0JP82_XENTR

UniProt

A0JP82 - A0JP82_XENTR

Protein
Submitted name:

LOC100036628 protein

Gene

tet3

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (12 Dec 2006)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi65 – 651Zinc 1Imported
    Metal bindingi68 – 681Zinc 1Imported
    Metal bindingi71 – 711Zinc 1Imported
    Metal bindingi77 – 771Zinc 2Imported
    Metal bindingi80 – 801Zinc 2Imported
    Metal bindingi83 – 831Zinc 2Imported
    Metal bindingi93 – 931Zinc 2Imported
    Metal bindingi98 – 981Zinc 1Imported

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. zinc ion binding Source: InterPro

    Keywords - Ligandi

    Metal-bindingImported, ZincImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    LOC100036628 proteinImported
    Gene namesi
    Name:tet3Imported
    Synonyms:LOC100036628Imported
    OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
    Taxonomic identifieri8364 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

    Organism-specific databases

    XenbaseiXB-GENE-877084. tet3.

    PTM / Processingi

    Proteomic databases

    PaxDbiA0JP82.

    Interactioni

    Protein-protein interaction databases

    STRINGi8364.ENSXETP00000026387.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4HP1X-ray2.25C58-111[»]
    4HP3X-ray2.05C58-111[»]
    ProteinModelPortaliA0JP82.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG76473.
    HOGENOMiHOG000154550.
    HOVERGENiHBG079550.

    Family and domain databases

    InterProiIPR024779. 2OGFeDO_nucleic_acid_mod.
    IPR002857. Znf_CXXC.
    [Graphical view]
    PfamiPF12851. Tet_JBP. 1 hit.
    PF02008. zf-CXXC. 1 hit.
    [Graphical view]
    PROSITEiPS51058. ZF_CXXC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0JP82-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDTQPAPVPH VLPQDVYEFP DDQESLGRLR VSEMPAELNG GGGGGSAAAF     50
    AMELPEQSNK KRKRCGVCVP CLRKEPCGAC YNCVNRSTSH QICKMRKCEQ 100
    LKKKRVVPMK GVENCSESIL VDGPKTDQME AGPVNHVQEG RLKQECDSTL 150
    PSKGCEDLAN QLLMEANSWL SNTAAPQDPC NKLNWDKPTI PNHAANNNSN 200
    LEDAKNLVAF SAVAEAMSTY GMPASGTPSS VSLQLYEKFN YETNRDNSGH 250
    LEGNAPSCPE DLNTLKAALA LAKHGVKPPN CNCDGPECPD YLEWLENKIK 300
    STVKGSQESP FPNLGQVSKE LVQKQYPKEQ VLNLENKNST CPSGNLPFSQ 350
    NALSLAKEKN ISLQTAIAIE ALTQLSSALP QTNNECPNAP SQPLINPHDQ 400
    LTHFPSAKGN QLPMLPVARN ELFQNQQSQL YTGKNALPVP QSPRQTSWEQ 450
    NKKSSYQEGQ YIPENLSHSS SVLPSDASTP QKPEFLQQWV QNADLLKSPS 500
    DPMTGLKQLL GNTDEYIKSV FKGPEALPNK KNVKPKHTIK SIKKESTEFL 550
    KMSPDQQLSQ LLQTNEFHRN TQAALQQHLH HKRNLFVDPN AMEACTQEQQ 600
    NWWVPSSQQA PVSKTTEKPV KERKKRRQSP SQKQVEPKPK PQRKQVQIKK 650
    PKVKEGSAVF MPVSQISLDT FRRVEKEENQ GKEMDAENSL PNNVQTELLE 700
    SQSLQLTGSQ ANPDDRKTVN TQEMCNENQS NIGKANNFAL CVNRANSFVA 750
    KDQCPTPSTH DTSSSSGQGD SANQHTNVSD VPGQNDLSCL DDKLEDLIRQ 800
    FEAEFGEDFS LPGSAVPSQN GEGPPKQTPS GDPQFKLPFP SQLLPPENST 850
    KPATHSNPAL SNNPVSREVS NNLDSLFSSK SPKQIKIESS GAITVVSTTC 900
    FYSEENQHLD GTPTKSDLPF NPTLSGFLDS PLKYLTSPTK SLIDTPAKKA 950
    QAEFPTCDCV EQINEKDEGP YYTHLGSGPT VASIRELMEE RFGQKGDAIR 1000
    IEKVIYTGKE GKSSRGCPIA KWVIRRQSED EKLMCLVRQR AGHHCENAVI 1050
    IILIMAWEGI PRSLGDSLYN DITETITKYG NPTSRRCGLN DDRTCACQGK 1100
    DPNTCGASFS FGCSWSMYFN GCKYARSKTP RKFRLIGENP KEEDGLKDNF 1150
    QNLATKVAPV YKMLAPQAYQ NQVNNEDIAI DCRLGLKEGR PFSGVTACMD 1200
    FCAHAHKDQH NLYNGCTVVC TLTKEDNRMI GRVAEDEQLH VLPLYKVSTT 1250
    DEFGSEEGQL EKIKKGGIHV LSSFPREVRK LSEPAKSCRQ RQLEAKKAAA 1300
    EKKKLQKEKL VSPDKTKQEP SDKKTCQQNP GVPQQQTKPC IKVEPSNHYN 1350
    NFKYNGNGVV ESYSVLGSCR PSDPYSMNSV YSYHSFYAQP NLPSVNGFHS 1400
    KYALPPFGFY GFPNNPVVPN QFMNYGTSDA RNSGWMNNCF EKKPELQSLA 1450
    DGMNQSYGSE LSEQSFRRSS EVPHHYSLQN PSSQKSVNVP HRTTPAPVET 1500
    TPYSNLPCYN KVIKKEPGSD PLVDSFQRAN SVHSHSPGVN HSLQASDLPI 1550
    SYKANGALSS SGRTNAESPC SMFMPNDKNG LEKKDYFGVH SNAPGLKDKQ 1600
    WPPYGTDVSV RQHDSLDSQS PGKVWSSCKL SDSSAALPSS ASTQDKNWNG 1650
    RQVSLNQGMK ESALFQEKLW NSVAASDRCS ATPSDRSSIT PCSELQDKNW 1700
    GSFPNPTVNS LKTDSSQNHW DPYSLDDNMD DGQSKSVKEE DDEEIWSDSE 1750
    HNFLDENIGG VAVAPGHGSI LIECARRELH ATTPLKKPNR CHPTRISLVF 1800
    YQHKNLNQPN HGLALWEAKM KQLAERARAR EEEAAKLGIK QEVKSLGKKR 1850
    KWGGAATTET PPVEKKDYTP TRQAATILTD SATTSFSYAY TKVTGPYSRF 1900
    I 1901
    Length:1,901
    Mass (Da):210,426
    Last modified:December 12, 2006 - v1
    Checksum:iC74D3B847C920212
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC127289 mRNA. Translation: AAI27290.1.
    RefSeqiNP_001090656.1. NM_001097187.1.
    UniGeneiStr.53063.

    Genome annotation databases

    GeneIDi100036628.
    KEGGixtr:100036628.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC127289 mRNA. Translation: AAI27290.1 .
    RefSeqi NP_001090656.1. NM_001097187.1.
    UniGenei Str.53063.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4HP1 X-ray 2.25 C 58-111 [» ]
    4HP3 X-ray 2.05 C 58-111 [» ]
    ProteinModelPortali A0JP82.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 8364.ENSXETP00000026387.

    Proteomic databases

    PaxDbi A0JP82.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 100036628.
    KEGGi xtr:100036628.

    Organism-specific databases

    CTDi 200424.
    Xenbasei XB-GENE-877084. tet3.

    Phylogenomic databases

    eggNOGi NOG76473.
    HOGENOMi HOG000154550.
    HOVERGENi HBG079550.

    Family and domain databases

    InterProi IPR024779. 2OGFeDO_nucleic_acid_mod.
    IPR002857. Znf_CXXC.
    [Graphical view ]
    Pfami PF12851. Tet_JBP. 1 hit.
    PF02008. zf-CXXC. 1 hit.
    [Graphical view ]
    PROSITEi PS51058. ZF_CXXC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Xenopus Gene Collection (XGC) project
      Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: TestesImported.
    2. "Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development."
      Xu Y., Xu C., Kato A., Tempel W., Abreu J.G., Bian C., Hu Y., Hu D., Zhao B., Cerovina T., Diao J., Wu F., He H.H., Cui Q., Clark E., Ma C., Barbara A., Veenstra G.J.
      , Xu G., Kaiser U.B., Liu X.S., Sugrue S.P., He X., Min J., Kato Y., Shi Y.G.
      Cell 151:1200-1213(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS) OF 58-111 IN COMPLEX WITH ZINC.

    Entry informationi

    Entry nameiA0JP82_XENTR
    AccessioniPrimary (citable) accession number: A0JP82
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 12, 2006
    Last sequence update: December 12, 2006
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3