<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

1. calcium ion binding Source: InterPro

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

1. homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
2. negative regulation of phosphatase activity Source: MGI

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Biological processⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Ligandⁱ

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componentⁱ

1. extracellular vesicular exosome Source: MGI
2. integral component of membrane Source: UniProtKB-KW
3. plasma membrane Source: InterPro

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Cellular componentⁱ

<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>Provides information on the tertiary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>Indicates if the canonical sequence displayed by default in the entry is complete or not.</p><p><a href='../manual/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MDLLSGTYIF AVLLACVVFQ SGAQEKNYTV REEMPENVLI GDLLKDLNLS 
        60         70         80         90        100
LIPDKSLTTP MQFKLVYKTG DVPLIRIEEG TGEIFTTGAR IDREKLCAGI 
       110        120        130        140        150
VLDARCFYEV EVAVLPDEIF RLVKIRFLIE DINDNAPLFP TTVINISIPE 
       160        170        180        190        200
NSAINSRYSL PAAIDPDIGI NGVQNYQLIK SQNIFGLDVI ETPEGDKMPQ 
       210        220        230        240        250
LIVQKELDRE EKDTYVMKVK VEDGGFPQRS STAILQVSVA DTNDNHPIFI 
       260        270        280        290        300
EKEIEVSIPE NAPIGSSVTQ LHATDADIGE NARIHFYFSN LVSNIAKRLF 
       310        320        330        340        350
HLNTTTGLIT VKEPLDREES PSHKLLVLAT DGGSTPARAT VLVNVTDIND 
       360        370        380        390        400
NVPSIDIRYI VNPTNGTVLL SENAPLNTKI ALITVMDKDS EHNGRVTCFT 
       410        420        430        440        450
DHEVPFRLRP VFSNQFLLET AAFLDFESTR EYAIKLLAAD AGKPPLNQSS 
       460        470        480        490        500
MLLIKVKDEN DNAPVFTQSF ISLSVPENNS PGAQLTKISA TDADSGQNAE 
       510        520        530        540        550
ISYMLGFDAP PEFNLDQRTG ILTAVKKLDR EKQEKYYFTV LAQDNGIPPL 
       560        570        580        590        600
MSNATVFVTV LDQNDNSPIF THNEYNFYVP ESLPKHGTVG LITVTDPDYG 
       610        620        630        640        650
ENSAVTLSIL DVNDQFTIDP QSGVIRPNIS FDRERQESYT FYVKAEDGGR 
       660        670        680        690        700
VSRSSTARVT INVVDVNDNK PIFIDPPSNY SFEWVLPSTN PGTVVFKVVA 
       710        720        730        740        750
IDDDIGMNAE VLYSIVGGNT KGLFMIEQTS GNITLKEKCM VSDLGLHRVI 
       760        770        780        790        800
VKANDLGQPD SLFNVVNVNF FINESVPNAT LIYELVRRSI DAPANQNTET 
       810        820        830        840        850
TSASSPTTDY VKIMVAIVAG TITVVLVIFI TAVVRCRQPP HLKASQKNKQ 
       860        870        880        890        900
NSEWVTPNPE NRQMIMMKKK KKKKKKHPPK NLLLNFVTIE EAKPDDGENE 
       910        920        930        940        950
RNSVTLDLPI ELEEQTMGKY NWGTTPTTFK PDSPDLARHY KSASPQPAFQ 
       960        970        980        990       1000
IQPETPLNSK HHIIQELPLD NTFVGCDSIS KCSSSSSDPY SVSECSYPVT 
      1010       1020       1030       1040       1050
TFKAPVSVHI RPTMKEVVRS HTPMKEATTV EIWTHPHPQS QRRVTFHLPE 
      1060       1070       1080       1090       1100
GSQESISDGG LGDHDAGSLP STSHALPLGY PQEEYFDHAA PNNRTEGDGN 
      1110       1120 
SDPESIPLHP SKTTASRSFH IHHTLLSN                       

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>Contains the literature citations that are the sources of data used to annotate the entry. Each reference is numbered and contains several subsections allowing a precise description of a given citation.</p><p><a href='../manual/publications_section' target='_top'>More...</a></p>Publicationsⁱ

1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
   The MGC Project Team
   Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.

   , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
   Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
   Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
   Tissue: PCR rescued clonesImported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • EMBL:AAI26931.1
   .
   
2. "Lineage-specific biology revealed by a finished genome assembly of the mouse."
   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.

   , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
   PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
   Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
   Strain: C57BL/6JImported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • Ensembl:ENSMUSP00000142050
   • Proteomes:UP000000589
   .
   
3. Ensembl
   Submitted (DEC-2014) to UniProtKB
   Cited for: IDENTIFICATION.
   Strain: C57BL/6JImported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • Ensembl:ENSMUSP00000142050
   .
   

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

External Data

<p>Provides links to the UniProt Reference Clusters (<a href="/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.</p><p><a href='../manual/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ