Pcdh11x

Functionⁱ

GO - Molecular functionⁱ

calcium ion binding Source: InterPro

GO - Biological processⁱ

homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
negative regulation of phosphatase activity Source: MGI

Keywordsⁱ

Biological process	Cell adhesionSAAS annotation
Ligand	CalciumSAAS annotation

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Pcdh11x proteinImported Submitted name: Protocadherin 11 X-linkedImported
Gene namesⁱ	Name:Pcdh11xImported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome X

Organism-specific databases

MGIⁱ	MGI:2442849. Pcdh11x.

Subcellular locationⁱ

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	813 – 834	HelicalSequence analysisAdd BLAST		22

GO - Cellular componentⁱ

extracellular exosome Source: MGI
integral component of membrane Source: UniProtKB-KW
plasma membrane Source: InterPro

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 23	Sequence analysisAdd BLAST		23
ChainⁱPRO_5010490518	24 – 1128	Sequence analysisAdd BLAST		1105

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000034755.

Bgeeⁱ

ENSMUSG00000034755.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000052340.

STRINGⁱ

10090.ENSMUSP00000052340.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	52 – 137	CAInterPro annotationAdd BLAST	86
Domainⁱ	161 – 247	CAInterPro annotationAdd BLAST	87
Domainⁱ	271 – 353	CAInterPro annotationAdd BLAST	83
Domainⁱ	383 – 464	CAInterPro annotationAdd BLAST	82
Domainⁱ	488 – 568	CAInterPro annotationAdd BLAST	81
Domainⁱ	592 – 671	CAInterPro annotationAdd BLAST	80
Domainⁱ	698 – 780	CAInterPro annotationAdd BLAST	83

Keywords - Domainⁱ

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG3594. Eukaryota. ENOG410XQHI. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00880000137846.
HOGENOMⁱ	HOG000234535.
HOVERGENⁱ	HBG053523.

Family and domain databases

InterProⁱ	View protein in InterPro IPR002126. Cadherin. IPR015919. Cadherin-like. IPR020894. Cadherin_CS. IPR013164. Cadherin_N. IPR013585. Protocadherin.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00028. Cadherin. 6 hits. PF08266. Cadherin_2. 1 hit. PF08374. Protocadherin. 1 hit.
PRINTSⁱ	PR00205. CADHERIN.
SMARTⁱ	View protein in SMART SM00112. CA. 7 hits.
SUPFAMⁱ	SSF49313. SSF49313. 6 hits.
PROSITEⁱ	View protein in PROSITE PS00232. CADHERIN_1. 4 hits.

Sequenceⁱ

Sequence statusⁱ: Complete.

A0JNT1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDLLSGTYIF AVLLACVVFQ SGAQEKNYTV REEMPENVLI GDLLKDLNLS 
        60         70         80         90        100
LIPDKSLTTP MQFKLVYKTG DVPLIRIEEG TGEIFTTGAR IDREKLCAGI 
       110        120        130        140        150
VLDARCFYEV EVAVLPDEIF RLVKIRFLIE DINDNAPLFP TTVINISIPE 
       160        170        180        190        200
NSAINSRYSL PAAIDPDIGI NGVQNYQLIK SQNIFGLDVI ETPEGDKMPQ 
       210        220        230        240        250
LIVQKELDRE EKDTYVMKVK VEDGGFPQRS STAILQVSVA DTNDNHPIFI 
       260        270        280        290        300
EKEIEVSIPE NAPIGSSVTQ LHATDADIGE NARIHFYFSN LVSNIAKRLF 
       310        320        330        340        350
HLNTTTGLIT VKEPLDREES PSHKLLVLAT DGGSTPARAT VLVNVTDIND 
       360        370        380        390        400
NVPSIDIRYI VNPTNGTVLL SENAPLNTKI ALITVMDKDS EHNGRVTCFT 
       410        420        430        440        450
DHEVPFRLRP VFSNQFLLET AAFLDFESTR EYAIKLLAAD AGKPPLNQSS 
       460        470        480        490        500
MLLIKVKDEN DNAPVFTQSF ISLSVPENNS PGAQLTKISA TDADSGQNAE 
       510        520        530        540        550
ISYMLGFDAP PEFNLDQRTG ILTAVKKLDR EKQEKYYFTV LAQDNGIPPL 
       560        570        580        590        600
MSNATVFVTV LDQNDNSPIF THNEYNFYVP ESLPKHGTVG LITVTDPDYG 
       610        620        630        640        650
ENSAVTLSIL DVNDQFTIDP QSGVIRPNIS FDRERQESYT FYVKAEDGGR 
       660        670        680        690        700
VSRSSTARVT INVVDVNDNK PIFIDPPSNY SFEWVLPSTN PGTVVFKVVA 
       710        720        730        740        750
IDDDIGMNAE VLYSIVGGNT KGLFMIEQTS GNITLKEKCM VSDLGLHRVI 
       760        770        780        790        800
VKANDLGQPD SLFNVVNVNF FINESVPNAT LIYELVRRSI DAPANQNTET 
       810        820        830        840        850
TSASSPTTDY VKIMVAIVAG TITVVLVIFI TAVVRCRQPP HLKASQKNKQ 
       860        870        880        890        900
NSEWVTPNPE NRQMIMMKKK KKKKKKHPPK NLLLNFVTIE EAKPDDGENE 
       910        920        930        940        950
RNSVTLDLPI ELEEQTMGKY NWGTTPTTFK PDSPDLARHY KSASPQPAFQ 
       960        970        980        990       1000
IQPETPLNSK HHIIQELPLD NTFVGCDSIS KCSSSSSDPY SVSECSYPVT 
      1010       1020       1030       1040       1050
TFKAPVSVHI RPTMKEVVRS HTPMKEATTV EIWTHPHPQS QRRVTFHLPE 
      1060       1070       1080       1090       1100
GSQESISDGG LGDHDAGSLP STSHALPLGY PQEEYFDHAA PNNRTEGDGN 
      1110       1120 
SDPESIPLHP SKTTASRSFH IHHTLLSN

Length:1,128

Mass (Da):124,895

Last modified:December 12, 2006 - v1

Checksum:ⁱB099293C344066DA

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC115298 Genomic DNA. No translation available. AC117258 Genomic DNA. No translation available. BX005163 Genomic DNA. No translation available. BX005240 Genomic DNA. No translation available. BX005446 Genomic DNA. No translation available. BX255884 Genomic DNA. No translation available. BC126930 mRNA. Translation: AAI26931.1.
UniGeneⁱ	Mm.39691. Mm.422941. Mm.490224.

Genome annotation databases

Ensemblⁱ	ENSMUST00000195088; ENSMUSP00000142050; ENSMUSG00000034755.
UCSC genome browser More...UCSCⁱ	uc009ueg.1. mouse.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC115298 Genomic DNA. No translation available. AC117258 Genomic DNA. No translation available. BX005163 Genomic DNA. No translation available. BX005240 Genomic DNA. No translation available. BX005446 Genomic DNA. No translation available. BX255884 Genomic DNA. No translation available. BC126930 mRNA. Translation: AAI26931.1.
UniGeneⁱ	Mm.39691. Mm.422941. Mm.490224.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000052340.

STRINGⁱ

10090.ENSMUSP00000052340.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000195088; ENSMUSP00000142050; ENSMUSG00000034755.
UCSC genome browser More...UCSCⁱ	uc009ueg.1. mouse.

Organism-specific databases

MGIⁱ	MGI:2442849. Pcdh11x.

Phylogenomic databases

eggNOGⁱ	KOG3594. Eukaryota. ENOG410XQHI. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00880000137846.
HOGENOMⁱ	HOG000234535.
HOVERGENⁱ	HBG053523.

Miscellaneous databases

ChiTaRSⁱ	Pcdh11x. mouse.
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000034755.

Bgeeⁱ

ENSMUSG00000034755.

Family and domain databases

InterProⁱ	View protein in InterPro IPR002126. Cadherin. IPR015919. Cadherin-like. IPR020894. Cadherin_CS. IPR013164. Cadherin_N. IPR013585. Protocadherin.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00028. Cadherin. 6 hits. PF08266. Cadherin_2. 1 hit. PF08374. Protocadherin. 1 hit.
PRINTSⁱ	PR00205. CADHERIN.
SMARTⁱ	View protein in SMART SM00112. CA. 7 hits.
SUPFAMⁱ	SSF49313. SSF49313. 6 hits.
PROSITEⁱ	View protein in PROSITE PS00232. CADHERIN_1. 4 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A0JNT1_MOUSE
Accessionⁱ	A0JNT1Primary (citable) accession number: A0JNT1
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	December 12, 2006
	Last sequence update:	December 12, 2006
	Last modified:	June 7, 2017
	This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A0JNT1 (A0JNT1_MOUSE)

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Pcdh11x protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ