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A0JNJ1

- STAC_BOVIN

UniProt

A0JNJ1 - STAC_BOVIN

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Protein

SH3 and cysteine-rich domain-containing protein

Gene

STAC

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Probably involved in a neuron-specific signal transduction.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri108 – 16053Phorbol-ester/DAG-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. intracellular signal transduction Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciCATTLE:524215-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
SH3 and cysteine-rich domain-containing protein
Alternative name(s):
Src homology 3 and cysteine-rich domain-containing protein
Gene namesi
Name:STAC
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Unplaced

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 403403SH3 and cysteine-rich domain-containing proteinPRO_0000274412Add
BLAST

Proteomic databases

PRIDEiA0JNJ1.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000008854.

Structurei

3D structure databases

ProteinModelPortaliA0JNJ1.
SMRiA0JNJ1. Positions 289-343.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini286 – 34560SH3PROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi103 – 1064Poly-Gly

Sequence similaritiesi

Contains 1 phorbol-ester/DAG-type zinc finger.PROSITE-ProRule annotation
Contains 1 SH3 domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri108 – 16053Phorbol-ester/DAG-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

SH3 domain, Zinc-finger

Phylogenomic databases

eggNOGiNOG82046.
HOGENOMiHOG000230980.
HOVERGENiHBG017859.
InParanoidiA0JNJ1.

Family and domain databases

InterProiIPR002219. PE/DAG-bd.
IPR011511. SH3_2.
IPR001452. SH3_domain.
IPR013315. Spectrin_alpha_SH3.
[Graphical view]
PfamiPF00130. C1_1. 1 hit.
PF00018. SH3_1. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
PR01887. SPECTRNALPHA.
SMARTiSM00109. C1. 1 hit.
SM00326. SH3. 2 hits.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0JNJ1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIPPSGARED GVDGLPKETA SAEQPPSPAS TGSQESKLQK LKRSLSFKTK
60 70 80 90 100
SLRSKSADNF FQRTNSDVKL QADVLAGVSP GSSPLPAPGS LTCTPTRAGL
110 120 130 140 150
YPGGGGKAHA FQEHIFKKPT FCDVCNHMIV GTNAKHGLRC KACKMSIHHK
160 170 180 190 200
CMDGLAPQRC MGKLPKGFRR YYSSPLLIHE QFGCIKEVMP IACGNKVDPV
210 220 230 240 250
YETLRFGTSL AQRTKKSSSG SGSDSPHRTS TSDLVEVPEE ADGPGDGYDL
260 270 280 290 300
RKRSNSVFTY PENGTDDFRD QAKNINHQGP LSKDPLQMNT YVALYKFVPQ
310 320 330 340 350
ENEDLEMRPG DMITLLEDSN EDWWKGKIQD RIGFFPANFV QRVHQNEKIF
360 370 380 390 400
RCVRTFSGCK EQGQITLKEN QICVASEEEQ DGFIRVLSGK KRGLVPLDVL

ENI
Length:403
Mass (Da):44,487
Last modified:December 12, 2006 - v1
Checksum:iEA90A0E47DCBD9FB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC126707 mRNA. Translation: AAI26708.1.
RefSeqiNP_001071430.1. NM_001077962.2.
UniGeneiBt.32379.

Genome annotation databases

GeneIDi524215.
KEGGibta:524215.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC126707 mRNA. Translation: AAI26708.1 .
RefSeqi NP_001071430.1. NM_001077962.2.
UniGenei Bt.32379.

3D structure databases

ProteinModelPortali A0JNJ1.
SMRi A0JNJ1. Positions 289-343.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000008854.

Proteomic databases

PRIDEi A0JNJ1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 524215.
KEGGi bta:524215.

Organism-specific databases

CTDi 6769.

Phylogenomic databases

eggNOGi NOG82046.
HOGENOMi HOG000230980.
HOVERGENi HBG017859.
InParanoidi A0JNJ1.

Enzyme and pathway databases

BioCyci CATTLE:524215-MONOMER.

Miscellaneous databases

NextBioi 20873920.

Family and domain databases

InterProi IPR002219. PE/DAG-bd.
IPR011511. SH3_2.
IPR001452. SH3_domain.
IPR013315. Spectrin_alpha_SH3.
[Graphical view ]
Pfami PF00130. C1_1. 1 hit.
PF00018. SH3_1. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view ]
PRINTSi PR00452. SH3DOMAIN.
PR01887. SPECTRNALPHA.
SMARTi SM00109. C1. 1 hit.
SM00326. SH3. 2 hits.
[Graphical view ]
SUPFAMi SSF50044. SSF50044. 1 hit.
PROSITEi PS50002. SH3. 1 hit.
PS00479. ZF_DAG_PE_1. 1 hit.
PS50081. ZF_DAG_PE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Hypothalamus.

Entry informationi

Entry nameiSTAC_BOVIN
AccessioniPrimary (citable) accession number: A0JNJ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: December 12, 2006
Last modified: October 29, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3