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A0JNJ1

- STAC_BOVIN

UniProt

A0JNJ1 - STAC_BOVIN

Protein

SH3 and cysteine-rich domain-containing protein

Gene

STAC

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (12 Dec 2006)
      Previous versions | rss
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    Functioni

    Probably involved in a neuron-specific signal transduction.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri108 – 16053Phorbol-ester/DAG-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. intracellular signal transduction Source: InterPro

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciCATTLE:524215-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    SH3 and cysteine-rich domain-containing protein
    Alternative name(s):
    Src homology 3 and cysteine-rich domain-containing protein
    Gene namesi
    Name:STAC
    OrganismiBos taurus (Bovine)
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Unplaced

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 403403SH3 and cysteine-rich domain-containing proteinPRO_0000274412Add
    BLAST

    Proteomic databases

    PRIDEiA0JNJ1.

    Interactioni

    Protein-protein interaction databases

    STRINGi9913.ENSBTAP00000008854.

    Structurei

    3D structure databases

    ProteinModelPortaliA0JNJ1.
    SMRiA0JNJ1. Positions 289-343.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini286 – 34560SH3PROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi103 – 1064Poly-Gly

    Sequence similaritiesi

    Contains 1 phorbol-ester/DAG-type zinc finger.PROSITE-ProRule annotation
    Contains 1 SH3 domain.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri108 – 16053Phorbol-ester/DAG-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    SH3 domain, Zinc-finger

    Phylogenomic databases

    eggNOGiNOG82046.
    HOGENOMiHOG000230980.
    HOVERGENiHBG017859.
    InParanoidiA0JNJ1.

    Family and domain databases

    InterProiIPR002219. Prot_Kinase_C-like_PE/DAG-bd.
    IPR011511. SH3_2.
    IPR001452. SH3_domain.
    IPR013315. Spectrin_alpha_SH3.
    [Graphical view]
    PfamiPF00130. C1_1. 1 hit.
    PF00018. SH3_1. 1 hit.
    PF07653. SH3_2. 1 hit.
    [Graphical view]
    PRINTSiPR00452. SH3DOMAIN.
    PR01887. SPECTRNALPHA.
    SMARTiSM00109. C1. 1 hit.
    SM00326. SH3. 2 hits.
    [Graphical view]
    SUPFAMiSSF50044. SSF50044. 1 hit.
    PROSITEiPS50002. SH3. 1 hit.
    PS00479. ZF_DAG_PE_1. 1 hit.
    PS50081. ZF_DAG_PE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0JNJ1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIPPSGARED GVDGLPKETA SAEQPPSPAS TGSQESKLQK LKRSLSFKTK    50
    SLRSKSADNF FQRTNSDVKL QADVLAGVSP GSSPLPAPGS LTCTPTRAGL 100
    YPGGGGKAHA FQEHIFKKPT FCDVCNHMIV GTNAKHGLRC KACKMSIHHK 150
    CMDGLAPQRC MGKLPKGFRR YYSSPLLIHE QFGCIKEVMP IACGNKVDPV 200
    YETLRFGTSL AQRTKKSSSG SGSDSPHRTS TSDLVEVPEE ADGPGDGYDL 250
    RKRSNSVFTY PENGTDDFRD QAKNINHQGP LSKDPLQMNT YVALYKFVPQ 300
    ENEDLEMRPG DMITLLEDSN EDWWKGKIQD RIGFFPANFV QRVHQNEKIF 350
    RCVRTFSGCK EQGQITLKEN QICVASEEEQ DGFIRVLSGK KRGLVPLDVL 400
    ENI 403
    Length:403
    Mass (Da):44,487
    Last modified:December 12, 2006 - v1
    Checksum:iEA90A0E47DCBD9FB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC126707 mRNA. Translation: AAI26708.1.
    RefSeqiNP_001071430.1. NM_001077962.2.
    UniGeneiBt.32379.

    Genome annotation databases

    GeneIDi524215.
    KEGGibta:524215.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC126707 mRNA. Translation: AAI26708.1 .
    RefSeqi NP_001071430.1. NM_001077962.2.
    UniGenei Bt.32379.

    3D structure databases

    ProteinModelPortali A0JNJ1.
    SMRi A0JNJ1. Positions 289-343.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9913.ENSBTAP00000008854.

    Proteomic databases

    PRIDEi A0JNJ1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 524215.
    KEGGi bta:524215.

    Organism-specific databases

    CTDi 6769.

    Phylogenomic databases

    eggNOGi NOG82046.
    HOGENOMi HOG000230980.
    HOVERGENi HBG017859.
    InParanoidi A0JNJ1.

    Enzyme and pathway databases

    BioCyci CATTLE:524215-MONOMER.

    Miscellaneous databases

    NextBioi 20873920.

    Family and domain databases

    InterProi IPR002219. Prot_Kinase_C-like_PE/DAG-bd.
    IPR011511. SH3_2.
    IPR001452. SH3_domain.
    IPR013315. Spectrin_alpha_SH3.
    [Graphical view ]
    Pfami PF00130. C1_1. 1 hit.
    PF00018. SH3_1. 1 hit.
    PF07653. SH3_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00452. SH3DOMAIN.
    PR01887. SPECTRNALPHA.
    SMARTi SM00109. C1. 1 hit.
    SM00326. SH3. 2 hits.
    [Graphical view ]
    SUPFAMi SSF50044. SSF50044. 1 hit.
    PROSITEi PS50002. SH3. 1 hit.
    PS00479. ZF_DAG_PE_1. 1 hit.
    PS50081. ZF_DAG_PE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Mammalian Gene Collection (MGC) project
      Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Hereford.
      Tissue: Hypothalamus.

    Entry informationi

    Entry nameiSTAC_BOVIN
    AccessioniPrimary (citable) accession number: A0JNJ1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 6, 2007
    Last sequence update: December 12, 2006
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3