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Protein
Submitted name:

Sp1 transcription factor

Gene

SP1

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-BTA-2173796. SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription.
R-BTA-2426168. Activation of gene expression by SREBF (SREBP).
R-BTA-6807505. RNA polymerase II transcribes snRNA genes.

Names & Taxonomyi

Protein namesi
Submitted name:
Sp1 transcription factorImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:SP1Imported
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 5

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSBTAG00000003021.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000003929.

Structurei

3D structure databases

ProteinModelPortaliA0JNC9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini627 – 656C2H2-typeInterPro annotationAdd BLAST30
Domaini657 – 686C2H2-typeInterPro annotationAdd BLAST30
Domaini687 – 714C2H2-typeInterPro annotationAdd BLAST28

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00760000118984.
HOGENOMiHOG000234295.
HOVERGENiHBG008933.
KOiK04684.
OMAiGWQIISS.
OrthoDBiEOG091G0HX6.
TreeFamiTF350150.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR030450. Sp1_fam.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR23235. PTHR23235. 1 hit.
SMARTiSM00355. ZnF_C2H2. 3 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0JNC9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDQDHSMDE MTAVVKIEKG VGGNNGGNGN GSGAFSQARS SSAGSSSSSG
60 70 80 90 100
GGGQESQPSP LALLAATCSR IESPNENSNN SQGPSQSGGT GELDLTATQL
110 120 130 140 150
SQGANGWQII SSSSGATPTS KEQSGSSTNG NNGSESSKNR TVSGGQYVVA
160 170 180 190 200
ATSNLQNQQV LTGLPGVMPN IQYQVIPQFQ TVDGQQLQFA ATGAQVQQDG
210 220 230 240 250
SGQIQIIPGA NQQIITNRGS GGNIIAAMPN LLQQAVPLQG LANNVLSGQT
260 270 280 290 300
QYVTNVPVAL NGNITLLPVN SVSAATLTPS SQAVTISSSG SQESGSQPVT
310 320 330 340 350
SGTAISSASL VSSQASSSSF FTNANSYSTT TTTSNMGIMN FTTSGSAGTS
360 370 380 390 400
SQSQTPQRVS GLQGSDTLNI QQNQTSGGSL QASQQKEGEQ NQQTQQQQQI
410 420 430 440 450
LIQPQLVQGG QALQALQAAP LSGQTFTTQA ITQETLQNLQ LQAVPNSGPI
460 470 480 490 500
IIRTPTVGPN GQVSWQTLQL QNLQVQNPQA QTITLAPMQG VSLGQTSSSS
510 520 530 540 550
TTLTPIASAA SIPAGTVTVN AAQLSSMPGL QTINLSALGA SGIQVHQLPS
560 570 580 590 600
LPLAIANASG DHGAQLGLHG AGGDGIHDDP TGGEEGENSP DPQPQAGRRT
610 620 630 640 650
RREACTCPYC KDSEGRGSGD PGKKKQHICH MQGCGKVYGK TSHLRAHLRW
660 670 680 690 700
HTGERPFMCT WSFCGKRFTR SDELQRHKRT HTGEKKFACP ECPKRFMRSD
710 720 730 740 750
HLSKHIKTHQ NKKGGPGVAL SVGTLPLDSG AGSEGSGTAT PSALITTNMV
760 770 780
AMEAICPEGI ARLANSGINV MQVADLQSIN ISGNGF
Length:786
Mass (Da):80,902
Last modified:December 12, 2006 - v1
Checksum:i0FD4F5665EAFD733
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02012861 Genomic DNA. No translation available.
DAAA02012862 Genomic DNA. No translation available.
BC126621 mRNA. Translation: AAI26622.1.
RefSeqiNP_001071495.1. NM_001078027.1.
UniGeneiBt.21241.

Genome annotation databases

EnsembliENSBTAT00000003929; ENSBTAP00000003929; ENSBTAG00000003021.
GeneIDi540741.
KEGGibta:540741.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02012861 Genomic DNA. No translation available.
DAAA02012862 Genomic DNA. No translation available.
BC126621 mRNA. Translation: AAI26622.1.
RefSeqiNP_001071495.1. NM_001078027.1.
UniGeneiBt.21241.

3D structure databases

ProteinModelPortaliA0JNC9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000003929.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000003929; ENSBTAP00000003929; ENSBTAG00000003021.
GeneIDi540741.
KEGGibta:540741.

Organism-specific databases

CTDi6667.

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00760000118984.
HOGENOMiHOG000234295.
HOVERGENiHBG008933.
KOiK04684.
OMAiGWQIISS.
OrthoDBiEOG091G0HX6.
TreeFamiTF350150.

Enzyme and pathway databases

ReactomeiR-BTA-2173796. SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription.
R-BTA-2426168. Activation of gene expression by SREBF (SREBP).
R-BTA-6807505. RNA polymerase II transcribes snRNA genes.

Gene expression databases

BgeeiENSBTAG00000003021.

Family and domain databases

Gene3Di3.30.160.60. 3 hits.
InterProiIPR030450. Sp1_fam.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PANTHERiPTHR23235. PTHR23235. 1 hit.
SMARTiSM00355. ZnF_C2H2. 3 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA0JNC9_BOVIN
AccessioniPrimary (citable) accession number: A0JNC9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: November 2, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.