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Protein
Submitted name:

Sp1 transcription factor

Gene

SP1

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-BTA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
R-BTA-6807505 RNA polymerase II transcribes snRNA genes

Names & Taxonomyi

Protein namesi
Submitted name:
Sp1 transcription factorImported
Gene namesi
Name:SP1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 5

Organism-specific databases

VGNCiVGNC:35152 SP1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSBTAG00000003021

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000003929

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini627 – 656C2H2-typeInterPro annotationAdd BLAST30
Domaini657 – 686C2H2-typeInterPro annotationAdd BLAST30
Domaini687 – 714C2H2-typeInterPro annotationAdd BLAST28

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00760000118984
HOGENOMiHOG000234295
HOVERGENiHBG008933
KOiK04684
OMAiCSRIESP
OrthoDBiEOG091G0HX6
TreeFamiTF350150

Family and domain databases

InterProiView protein in InterPro
IPR030449 SP1
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR23235:SF16 PTHR23235:SF16, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF57667 SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequencei

Sequence statusi: Complete.

A0JNC9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDQDHSMDE MTAVVKIEKG VGGNNGGNGN GSGAFSQARS SSAGSSSSSG
60 70 80 90 100
GGGQESQPSP LALLAATCSR IESPNENSNN SQGPSQSGGT GELDLTATQL
110 120 130 140 150
SQGANGWQII SSSSGATPTS KEQSGSSTNG NNGSESSKNR TVSGGQYVVA
160 170 180 190 200
ATSNLQNQQV LTGLPGVMPN IQYQVIPQFQ TVDGQQLQFA ATGAQVQQDG
210 220 230 240 250
SGQIQIIPGA NQQIITNRGS GGNIIAAMPN LLQQAVPLQG LANNVLSGQT
260 270 280 290 300
QYVTNVPVAL NGNITLLPVN SVSAATLTPS SQAVTISSSG SQESGSQPVT
310 320 330 340 350
SGTAISSASL VSSQASSSSF FTNANSYSTT TTTSNMGIMN FTTSGSAGTS
360 370 380 390 400
SQSQTPQRVS GLQGSDTLNI QQNQTSGGSL QASQQKEGEQ NQQTQQQQQI
410 420 430 440 450
LIQPQLVQGG QALQALQAAP LSGQTFTTQA ITQETLQNLQ LQAVPNSGPI
460 470 480 490 500
IIRTPTVGPN GQVSWQTLQL QNLQVQNPQA QTITLAPMQG VSLGQTSSSS
510 520 530 540 550
TTLTPIASAA SIPAGTVTVN AAQLSSMPGL QTINLSALGA SGIQVHQLPS
560 570 580 590 600
LPLAIANASG DHGAQLGLHG AGGDGIHDDP TGGEEGENSP DPQPQAGRRT
610 620 630 640 650
RREACTCPYC KDSEGRGSGD PGKKKQHICH MQGCGKVYGK TSHLRAHLRW
660 670 680 690 700
HTGERPFMCT WSFCGKRFTR SDELQRHKRT HTGEKKFACP ECPKRFMRSD
710 720 730 740 750
HLSKHIKTHQ NKKGGPGVAL SVGTLPLDSG AGSEGSGTAT PSALITTNMV
760 770 780
AMEAICPEGI ARLANSGINV MQVADLQSIN ISGNGF
Length:786
Mass (Da):80,902
Last modified:December 12, 2006 - v1
Checksum:i0FD4F5665EAFD733
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02012861 Genomic DNA No translation available.
DAAA02012862 Genomic DNA No translation available.
BC126621 mRNA Translation: AAI26622.1
RefSeqiNP_001071495.1, NM_001078027.1
UniGeneiBt.21241

Genome annotation databases

EnsembliENSBTAT00000003929; ENSBTAP00000003929; ENSBTAG00000003021
GeneIDi540741
KEGGibta:540741

Similar proteinsi

Entry informationi

Entry nameiA0JNC9_BOVIN
AccessioniPrimary (citable) accession number: A0JNC9
Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: March 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health