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Protein
Submitted name:

Neu3.3

Gene

neu3.3

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • exo-alpha-sialidase activity Source: ZFIN

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-1660662. Glycosphingolipid metabolism.
R-DRE-4085001. Sialic acid metabolism.

Protein family/group databases

CAZyiGH33. Glycoside Hydrolase Family 33.

Names & Taxonomyi

Protein namesi
Submitted name:
Neu3.3Imported
Submitted name:
Neu3.3 proteinImported
Submitted name:
Sialidase 3 (membrane sialidase), tandem duplicate 3Imported
Submitted name:
Sialidase 3.3Imported
Gene namesi
Name:neu3.3Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 21

Organism-specific databases

ZFINiZDB-GENE-061103-511. neu3.3.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: GO_Central
  • intracellular membrane-bounded organelle Source: GO_Central
  • membrane Source: ZFIN

Expressioni

Gene expression databases

BgeeiENSDARG00000058327.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000075627.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 375SialidasesInterPro annotationAdd BLAST322

Phylogenomic databases

eggNOGiENOG410IFVF. Eukaryota.
ENOG410Y74Z. LUCA.
GeneTreeiENSGT00390000011171.
HOGENOMiHOG000233778.
HOVERGENiHBG052608.
KOiK12357.
OMAiINARNSC.
OrthoDBiEOG091G08BI.
TreeFamiTF331063.

Family and domain databases

InterProiView protein in InterPro
IPR026944. Sialidase-3.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
PANTHERiPTHR10628. PTHR10628. 1 hit.
PTHR10628:SF26. PTHR10628:SF26. 1 hit.
PfamiView protein in Pfam
PF13088. BNR_2. 1 hit.
SUPFAMiSSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

A0JMM3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNKTPSKSK SGYPKEMNTT TVFKQEQPQT WCCCFKKQVS YRIPALVYVS
60 70 80 90 100
DEQTFLAFAE KRKTLNDTNA EVLVMRRGTW VDAKTKEVEW ICGHQVLSSA
110 120 130 140 150
SLPNHRSMNP CPVYERDSKT LFLFFVCVPT QVSEFDQIRT NKSQGRLCYV
160 170 180 190 200
TSKDAGKTWS QTIDLTADVI GEQVNEWAPF AVGPGHGVQT KNGRLIIPAY
210 220 230 240 250
AYRYTGKTDC TSCCCLSFCC FTPYALAFYS DDQGITWKAG QQMDVESCEC
260 270 280 290 300
QMAEIVGEKG DSTLYCNART RLGYRTEALS NNAGEDFDTV LSSSKLIETG
310 320 330 340 350
KGCQGSVLSF VEQSSPPQTW LLYSHPSHPK KRVDLGLYLN KSPLDSSGWS
360 370 380 390 400
DEPLMILHHG PSAYSDLVEF EPGHFACLME CGKEHENEEI AFLLFKLPEK

KL
Length:402
Mass (Da):45,094
Last modified:December 12, 2006 - v1
Checksum:iAF2867F30357419E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928016 Genomic DNA. No translation available.
BC125931 mRNA. Translation: AAI25932.1.
BC164496 mRNA. Translation: AAI64496.1.
EF107698 mRNA. Translation: ABO30989.1.
RefSeqiNP_001071006.1. NM_001077538.1.
XP_017208270.1. XM_017352781.1.
UniGeneiDr.91877.

Genome annotation databases

EnsembliENSDART00000081184; ENSDARP00000075627; ENSDARG00000058327.
ENSDART00000084600; ENSDARP00000079035; ENSDARG00000058327.
GeneIDi555206.
KEGGidre:555206.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA0JMM3_DANRE
AccessioniPrimary (citable) accession number: A0JMM3
Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: June 7, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported