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Protein
Submitted name:

Sphingosine-1-phosphate receptor 1

Gene

s1pr1

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-XTR-418594 G alpha (i) signalling events
R-XTR-419408 Lysosphingolipid and LPA receptors

Names & Taxonomyi

Protein namesi
Submitted name:
Sphingosine-1-phosphate receptor 1Imported
Gene namesi
Name:s1pr1Imported
Synonyms:MGC147427Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-977003 s1pr1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei42 – 63HelicalSequence analysisAdd BLAST22
Transmembranei75 – 96HelicalSequence analysisAdd BLAST22
Transmembranei116 – 132HelicalSequence analysisAdd BLAST17
Transmembranei153 – 174HelicalSequence analysisAdd BLAST22
Transmembranei194 – 220HelicalSequence analysisAdd BLAST27
Transmembranei245 – 267HelicalSequence analysisAdd BLAST23
Transmembranei287 – 306HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSXETG00000013266

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000029045

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 303G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST250

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IIA7 Eukaryota
ENOG410XQD3 LUCA
GeneTreeiENSGT00760000118804
HOGENOMiHOG000233501
HOVERGENiHBG103071
KOiK04288
OMAiTAYTANI
OrthoDBiEOG091G0DD4
TreeFamiTF330052

Family and domain databases

InterProiView protein in InterPro
IPR000987 EDG1_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR004061 S1P_rcpt
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00642 EDG1RECEPTOR
PR00237 GPCRRHODOPSN
PR01523 S1PRECEPTOR
SMARTiView protein in SMART
SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0JM96-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPTSATQRR NEYYDHEIII EHYNYTGKYK GNLSTDIKPT SIIFIIICCF
60 70 80 90 100
IVLENILVLL TIWRTKKFHR PMYYFIGNLA LSDLLAGTAY TANILLSGPH
110 120 130 140 150
TYKLTPVEWL IREGSMFVAL SASVFSLVAI AIERYITMLK MKLHNGSKSS
160 170 180 190 200
RSFLLISGCW ILSLFLGGLP IMGWNCIKQI SACSTVLPLY HKHYILFCTT
210 220 230 240 250
IFCALLMAIV ILYARIYFLV RTRSRSLTFK RNLARPSRSS EKSMALLKTV
260 270 280 290 300
IIVLSVFILC WSPLFIFLLL DFGCKVKTCP VLFKAEYFLS LAVLNSATNP
310 320 330 340 350
IIYTLTNREM RRAFLKMACC SHCSIFGSSS KVKRPIITGM EFSRSKSDNS
360 370
SHPQKDEGEY PVTLMSSGNV TSSS
Length:374
Mass (Da):42,371
Last modified:December 12, 2006 - v1
Checksum:iB6C94FB5902BFDD1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01030668 Genomic DNA No translation available.
BC125793 mRNA Translation: AAI25794.1
RefSeqiNP_001072893.1, NM_001079425.1
UniGeneiStr.18760

Genome annotation databases

EnsembliENSXETT00000029045; ENSXETP00000029045; ENSXETG00000013266
GeneIDi780355
KEGGixtr:780355

Similar proteinsi

Entry informationi

Entry nameiA0JM96_XENTR
AccessioniPrimary (citable) accession number: A0JM96
Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: February 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health