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Protein

Synaptotagmin-4

Gene

SYT4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in membrane trafficking.By similarity

Cofactori

Ca2+By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi280 – 2801CalciumBy similarity
Metal bindingi286 – 2861CalciumBy similarity
Metal bindingi336 – 3361CalciumBy similarity
Metal bindingi338 – 3381CalciumBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Calcium, Lipid-binding, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Synaptotagmin-4
Alternative name(s):
NTMC2T2.2
Synaptotagmin D
Gene namesi
Name:SYT4
Synonyms:SYTD
Ordered Locus Names:At5g11100
ORF Names:T5K6.90
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G11100.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 569569Synaptotagmin-4PRO_0000419241Add
BLAST

Proteomic databases

PaxDbiA0JJX5.
PRIDEiA0JJX5.

PTM databases

iPTMnetiA0JJX5.

Expressioni

Gene expression databases

GenevisibleiA0JJX5. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G11100.1.

Structurei

3D structure databases

ProteinModelPortaliA0JJX5.
SMRiA0JJX5. Positions 259-559.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini251 – 350100C2 1PROSITE-ProRule annotationAdd
BLAST
Domaini430 – 52798C2 2PROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni229 – 531303Phospholipid bindingBy similarityAdd
BLAST

Sequence similaritiesi

Belongs to the synaptotagmin family.Curated
Contains 2 C2 domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1012. Eukaryota.
COG5038. LUCA.
InParanoidiA0JJX5.
OMAiHLTVRVF.
PhylomeDBiA0JJX5.

Family and domain databases

Gene3Di2.60.40.150. 3 hits.
InterProiIPR000008. C2_dom.
IPR031468. SMP_LBD.
[Graphical view]
PfamiPF00168. C2. 2 hits.
PF17047. SMP_LBD. 1 hit.
[Graphical view]
SMARTiSM00239. C2. 2 hits.
[Graphical view]
SUPFAMiSSF49562. SSF49562. 2 hits.
PROSITEiPS50004. C2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0JJX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGFLFGLFIG IAVSFGLVVA FARYSSVRST RRADLAKTIA AFARMTVQDS
60 70 80 90 100
RKLLPGDFYP SWVVFSQRQK LNWLNLELEK IWPYVNEAAS ELIKSSVEPV
110 120 130 140 150
LEQYTPAMLA SLKFSKFTLG TVAPQFTGVS ILESESGPNG ITMELEMQWD
160 170 180 190 200
GNPKIVLDVK TLLGVSLPIE VKNIGFTGVF RLIFKPLVDE FPCFGALSYS
210 220 230 240 250
LREKKGLDFT LKVIGGELTS IPGISDAIEE TIRDAIEDSI TWPVRKIIPI
260 270 280 290 300
LPGDYSDLEL KPVGKLDVKV VQAKDLANKD MIGKSDPYAI VFIRPLPDRT
310 320 330 340 350
KKTKTISNSL NPIWNEHFEF IVEDVSTQHL TVRVFDDEGV GSSQLIGAAQ
360 370 380 390 400
VPLNELVPGK VKDIWLKLVK DLEIQRDTKN RGQVQLELLY CPLGKEGGLK
410 420 430 440 450
NPFNPDYSLT ILEKVLKPES EDSDATDMKK LVTSKKKDVI VRGVLSVTVV
460 470 480 490 500
AAEDLPAVDF MGKADAFVVI TLKKSETKSK TRVVPDSLNP VWNQTFDFVV
510 520 530 540 550
EDALHDLLTL EVWDHDKFGK DKIGRVIMTL TRVMLEGEFQ EWFELDGAKS
560
GKLCVHLKWT PRLKLRDAS
Length:569
Mass (Da):63,609
Last modified:December 12, 2006 - v1
Checksum:i396D0ED18C4A4454
GO

Sequence cautioni

The sequence CAC03458.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM410051 mRNA. Translation: CAL64988.1.
AL391222 Genomic DNA. Translation: CAC03458.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED91635.1.
PIRiT51799.
RefSeqiNP_196671.2. NM_121148.3.
UniGeneiAt.54810.

Genome annotation databases

EnsemblPlantsiAT5G11100.1; AT5G11100.1; AT5G11100.
GeneIDi830978.
GrameneiAT5G11100.1; AT5G11100.1; AT5G11100.
KEGGiath:AT5G11100.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM410051 mRNA. Translation: CAL64988.1.
AL391222 Genomic DNA. Translation: CAC03458.1. Sequence problems.
CP002688 Genomic DNA. Translation: AED91635.1.
PIRiT51799.
RefSeqiNP_196671.2. NM_121148.3.
UniGeneiAt.54810.

3D structure databases

ProteinModelPortaliA0JJX5.
SMRiA0JJX5. Positions 259-559.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G11100.1.

PTM databases

iPTMnetiA0JJX5.

Proteomic databases

PaxDbiA0JJX5.
PRIDEiA0JJX5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G11100.1; AT5G11100.1; AT5G11100.
GeneIDi830978.
GrameneiAT5G11100.1; AT5G11100.1; AT5G11100.
KEGGiath:AT5G11100.

Organism-specific databases

TAIRiAT5G11100.

Phylogenomic databases

eggNOGiKOG1012. Eukaryota.
COG5038. LUCA.
InParanoidiA0JJX5.
OMAiHLTVRVF.
PhylomeDBiA0JJX5.

Miscellaneous databases

PROiA0JJX5.

Gene expression databases

GenevisibleiA0JJX5. AT.

Family and domain databases

Gene3Di2.60.40.150. 3 hits.
InterProiIPR000008. C2_dom.
IPR031468. SMP_LBD.
[Graphical view]
PfamiPF00168. C2. 2 hits.
PF17047. SMP_LBD. 1 hit.
[Graphical view]
SMARTiSM00239. C2. 2 hits.
[Graphical view]
SUPFAMiSSF49562. SSF49562. 2 hits.
PROSITEiPS50004. C2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans."
    Craxton M.
    BMC Genomics 8:259-259(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
    Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.
    , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
    Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.

Entry informationi

Entry nameiSYT4_ARATH
AccessioniPrimary (citable) accession number: A0JJX5
Secondary accession number(s): Q9FY55
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2012
Last sequence update: December 12, 2006
Last modified: February 17, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.