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Protein

Synaptotagmin-4

Gene

SYT4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in membrane trafficking.By similarity

Cofactori

Ca2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi280CalciumBy similarity1
Metal bindingi286CalciumBy similarity1
Metal bindingi336CalciumBy similarity1
Metal bindingi338CalciumBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processLipid transport, Transport
LigandCalcium, Lipid-binding, Metal-binding

Enzyme and pathway databases

ReactomeiR-ATH-1660662 Glycosphingolipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Synaptotagmin-4
Alternative name(s):
NTMC2T2.2
Synaptotagmin D
Gene namesi
Name:SYT4
Synonyms:SYTD
Ordered Locus Names:At5g11100
ORF Names:T5K6.90
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G11100
TAIRilocus:2184931 AT5G11100

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1 – 21HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004192411 – 569Synaptotagmin-4Add BLAST569

Proteomic databases

PaxDbiA0JJX5
PRIDEiA0JJX5

Expressioni

Gene expression databases

ExpressionAtlasiA0JJX5 baseline and differential
GenevisibleiA0JJX5 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G11100.1

Structurei

3D structure databases

ProteinModelPortaliA0JJX5
SMRiA0JJX5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 251SMP-LTDPROSITE-ProRule annotationAdd BLAST185
Domaini251 – 350C2 1PROSITE-ProRule annotationAdd BLAST100
Domaini430 – 527C2 2PROSITE-ProRule annotationAdd BLAST98

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni229 – 531Phospholipid bindingBy similarityAdd BLAST303

Sequence similaritiesi

Belongs to the synaptotagmin family.Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1012 Eukaryota
COG5038 LUCA
InParanoidiA0JJX5
OMAiFQEWFEL
OrthoDBiEOG093605MC
PhylomeDBiA0JJX5

Family and domain databases

Gene3Di2.60.40.150, 2 hits
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR031468 SMP_LBD
PfamiView protein in Pfam
PF00168 C2, 2 hits
PF17047 SMP_LBD, 1 hit
SMARTiView protein in SMART
SM00239 C2, 2 hits
PROSITEiView protein in PROSITE
PS50004 C2, 2 hits
PS51847 SMP, 1 hit

Sequencei

Sequence statusi: Complete.

A0JJX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGFLFGLFIG IAVSFGLVVA FARYSSVRST RRADLAKTIA AFARMTVQDS
60 70 80 90 100
RKLLPGDFYP SWVVFSQRQK LNWLNLELEK IWPYVNEAAS ELIKSSVEPV
110 120 130 140 150
LEQYTPAMLA SLKFSKFTLG TVAPQFTGVS ILESESGPNG ITMELEMQWD
160 170 180 190 200
GNPKIVLDVK TLLGVSLPIE VKNIGFTGVF RLIFKPLVDE FPCFGALSYS
210 220 230 240 250
LREKKGLDFT LKVIGGELTS IPGISDAIEE TIRDAIEDSI TWPVRKIIPI
260 270 280 290 300
LPGDYSDLEL KPVGKLDVKV VQAKDLANKD MIGKSDPYAI VFIRPLPDRT
310 320 330 340 350
KKTKTISNSL NPIWNEHFEF IVEDVSTQHL TVRVFDDEGV GSSQLIGAAQ
360 370 380 390 400
VPLNELVPGK VKDIWLKLVK DLEIQRDTKN RGQVQLELLY CPLGKEGGLK
410 420 430 440 450
NPFNPDYSLT ILEKVLKPES EDSDATDMKK LVTSKKKDVI VRGVLSVTVV
460 470 480 490 500
AAEDLPAVDF MGKADAFVVI TLKKSETKSK TRVVPDSLNP VWNQTFDFVV
510 520 530 540 550
EDALHDLLTL EVWDHDKFGK DKIGRVIMTL TRVMLEGEFQ EWFELDGAKS
560
GKLCVHLKWT PRLKLRDAS
Length:569
Mass (Da):63,609
Last modified:December 12, 2006 - v1
Checksum:i396D0ED18C4A4454
GO

Sequence cautioni

The sequence CAC03458 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM410051 mRNA Translation: CAL64988.1
AL391222 Genomic DNA Translation: CAC03458.1 Sequence problems.
CP002688 Genomic DNA Translation: AED91635.1
PIRiT51799
RefSeqiNP_196671.2, NM_121148.3
UniGeneiAt.54810

Genome annotation databases

GeneIDi830978
KEGGiath:AT5G11100

Similar proteinsi

Entry informationi

Entry nameiSYT4_ARATH
AccessioniPrimary (citable) accession number: A0JJX5
Secondary accession number(s): Q9FY55
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2012
Last sequence update: December 12, 2006
Last modified: May 23, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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