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Protein
Submitted name:

Insulin-like growth factor II

Gene

IGF2

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

  1. fin regeneration Source: Ensembl
  2. forebrain development Source: Ensembl
  3. notochord development Source: Ensembl
  4. pronephros development Source: Ensembl
  5. somitogenesis Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor IIImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:IGF2Imported
Synonyms:igf-2Imported
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
ProteomesiUP000005226: Unplaced

Subcellular locationi

Secreted UniRule annotationSAAS annotation

GO - Cellular componenti

  1. extracellular space Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000024016.

Structurei

3D structure databases

ProteinModelPortaliA0JGX5.
SMRiA0JGX5. Positions 53-117.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the insulin family.UniRule annotation

Phylogenomic databases

eggNOGiNOG44017.
GeneTreeiENSGT00530000063856.
HOGENOMiHOG000233362.
KOiK13769.
OMAiALQFVCE.
OrthoDBiEOG7TF7CG.
TreeFamiTF332820.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR022334. IGF2.
IPR013576. IGF2_C.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF08365. IGF2_C. 1 hit.
PF00049. Insulin. 2 hits.
[Graphical view]
PRINTSiPR02002. INSLNLIKEGF.
PR02006. INSLNLIKEGF2.
PR00276. INSULINFAMLY.
ProDomiPD005188. IGF2_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0JGX5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
METQHRNAAP SFCHTCRRTE ISIMKVKKMS SSSHALLFAL ALTLYVVEVT
60 70 80 90 100
SIETLCGGEL VDALQFVCED RGFYFSRPTS RGSSRRTQNR GIVEECCFRS
110 120 130 140 150
CDLKLMEQYC AKPAKSERDV SATSLQVIPV MPAVKQEVPR KQHVTVKHSK
160 170 180 190 200
YEVWQRKAAQ RLRRGVPAIL RAKKFRRQAE KIKAQEQTVF HRPLISLPSK
210
LPPVLLTTDS YINHK
Length:215
Mass (Da):24,561
Last modified:December 12, 2006 - v1
Checksum:i591363D62F330550
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021880 Genomic DNA. Translation: CAA17123.1.
RefSeqiXP_003967407.1. XM_003967358.1.
UniGeneiTru.4144.

Genome annotation databases

EnsembliENSTRUT00000024115; ENSTRUP00000024016; ENSTRUG00000009557.
GeneIDi100462940.
KEGGitru:100462940.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021880 Genomic DNA. Translation: CAA17123.1.
RefSeqiXP_003967407.1. XM_003967358.1.
UniGeneiTru.4144.

3D structure databases

ProteinModelPortaliA0JGX5.
SMRiA0JGX5. Positions 53-117.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000024016.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSTRUT00000024115; ENSTRUP00000024016; ENSTRUG00000009557.
GeneIDi100462940.
KEGGitru:100462940.

Organism-specific databases

CTDi100462940.

Phylogenomic databases

eggNOGiNOG44017.
GeneTreeiENSGT00530000063856.
HOGENOMiHOG000233362.
KOiK13769.
OMAiALQFVCE.
OrthoDBiEOG7TF7CG.
TreeFamiTF332820.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR022334. IGF2.
IPR013576. IGF2_C.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF08365. IGF2_C. 1 hit.
PF00049. Insulin. 2 hits.
[Graphical view]
PRINTSiPR02002. INSLNLIKEGF.
PR02006. INSLNLIKEGF2.
PR00276. INSULINFAMLY.
ProDomiPD005188. IGF2_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
  2. Clark M.S.
    Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Hd-rRImported.
  4. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiA0JGX5_TAKRU
AccessioniPrimary (citable) accession number: A0JGX5
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: February 4, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.