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Protein
Submitted name:

Insulin-like growth factor II

Gene

IGF2

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor IIImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:IGF2Imported
Synonyms:igf2Imported
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
Proteomesi
  • UP000005226 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Secreted UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000024016.

Structurei

3D structure databases

SMRiA0JGX5. Positions 53-117.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini53 – 11058IlGFInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the insulin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IY3P. Eukaryota.
ENOG4111KP2. LUCA.
GeneTreeiENSGT00530000063856.
HOGENOMiHOG000233362.
KOiK13769.
OMAiALQFVCE.
OrthoDBiEOG091G0H56.
TreeFamiTF332820.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR022334. IGF2.
IPR013576. IGF2_C.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF08365. IGF2_C. 1 hit.
PF00049. Insulin. 2 hits.
[Graphical view]
PRINTSiPR02002. INSLNLIKEGF.
PR02006. INSLNLIKEGF2.
PR00276. INSULINFAMLY.
ProDomiPD005188. IGF2_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0JGX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METQHRNAAP SFCHTCRRTE ISIMKVKKMS SSSHALLFAL ALTLYVVEVT
60 70 80 90 100
SIETLCGGEL VDALQFVCED RGFYFSRPTS RGSSRRTQNR GIVEECCFRS
110 120 130 140 150
CDLKLMEQYC AKPAKSERDV SATSLQVIPV MPAVKQEVPR KQHVTVKHSK
160 170 180 190 200
YEVWQRKAAQ RLRRGVPAIL RAKKFRRQAE KIKAQEQTVF HRPLISLPSK
210
LPPVLLTTDS YINHK
Length:215
Mass (Da):24,561
Last modified:December 12, 2006 - v1
Checksum:i591363D62F330550
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021880 Genomic DNA. Translation: CAA17123.1.
RefSeqiXP_003967407.1. XM_003967358.2.
UniGeneiTru.4144.

Genome annotation databases

EnsembliENSTRUT00000024115; ENSTRUP00000024016; ENSTRUG00000009557.
GeneIDi100462940.
KEGGitru:100462940.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021880 Genomic DNA. Translation: CAA17123.1.
RefSeqiXP_003967407.1. XM_003967358.2.
UniGeneiTru.4144.

3D structure databases

SMRiA0JGX5. Positions 53-117.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000024016.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSTRUT00000024115; ENSTRUP00000024016; ENSTRUG00000009557.
GeneIDi100462940.
KEGGitru:100462940.

Organism-specific databases

CTDi3481.

Phylogenomic databases

eggNOGiENOG410IY3P. Eukaryota.
ENOG4111KP2. LUCA.
GeneTreeiENSGT00530000063856.
HOGENOMiHOG000233362.
KOiK13769.
OMAiALQFVCE.
OrthoDBiEOG091G0H56.
TreeFamiTF332820.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR022334. IGF2.
IPR013576. IGF2_C.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF08365. IGF2_C. 1 hit.
PF00049. Insulin. 2 hits.
[Graphical view]
PRINTSiPR02002. INSLNLIKEGF.
PR02006. INSLNLIKEGF2.
PR00276. INSULINFAMLY.
ProDomiPD005188. IGF2_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA0JGX5_TAKRU
AccessioniPrimary (citable) accession number: A0JGX5
Entry historyi
Integrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: September 7, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.