A0FKR4 (A0FKR4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Vascular endothelial growth factor A isoform 5 EMBL ABK27265.1

Gene names

Name:

Vegfa MGI 103178

Organism

Mus musculus (Mouse) EMBL ABK27265.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	123 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the PDGF/VEGF growth factor family. RuleBase RU003818

Ontologies

Keywords
Molecular function	Growth factor SAAS SAAS000072 RuleBase RU003818 Mitogen RuleBase RU003819
Gene Ontology (GO)
Biological process	positive regulation of cell division Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	membrane Inferred from electronic annotation. Source: InterPro
Molecular function	growth factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	123	1	EMBL ABK27265.1

Sequences

	Sequence		Length	Mass (Da)
	A0FKR4 [UniParc]. Last modified November 28, 2006. Version 1. Checksum: 0B017ACBFB3A1A8C	FASTA	123	14,397
	10 20 30 40 50 60 MNFLLSWVHW TLALLLYLHH AKWSQAAPTT EGEQKSHEVI KFMDVYQRSY CRPIETLVDI 70 80 90 100 110 120 FQEYPDEIEY IFKPSCVPLM RCAGCCNDEA LECVPTSESN ITMQIMRIKP HQSQHIGEMS FLQ

References

[1]	"Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression." Obrosova I.G., Minchenko A.G., Frank R.N., Seigel G.M., Zsengeller Z., Pacher P., Stevens M.J., Szabo C. Int. J. Mol. Med. 14:55-64(2004) [PubMed: 15202016] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL ABK27265.1. Tissue: Retina EMBL ABK27265.1.
[2]	"Unusual alternatively spliced variants of mouse VEGF with deletions in 5' UTR." Minchenko O.H., Moenner M., Minchenko D.O., Kovtun O.O., Bikfalvi A., Esumi H. Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL ABK27265.1. Tissue: Retina EMBL ABK27265.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EF028705 mRNA. Translation: ABK27265.1.
IPI	IPI00989242.
UniGene	Mm.282184.
3D structure databases
ProteinModelPortal	A0FKR4.
ModBase	Search...
Protein-protein interaction databases
STRING	A0FKR4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	roNOG06684.
HOVERGEN	HBG000105.
InParanoid	A0FKR4.
Gene expression databases
Bgee	A0FKR4.
Genevestigator	A0FKR4.
Family and domain databases
InterPro	IPR000072. PD_growth_factor. IPR023581. PD_growth_factor_CS. [Graphical view]
Pfam	PF00341. PDGF. 1 hit. [Graphical view]
SMART	SM00141. PDGF. 1 hit. [Graphical view]
PROSITE	PS00249. PDGF_1. 1 hit. PS50278. PDGF_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0FKR4_MOUSE

Accession

Primary (citable) accession number: A0FKR4

Entry history

Integrated into UniProtKB/TrEMBL:	November 28, 2006
Last sequence update:	November 28, 2006
Last modified:	June 28, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)