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Protein

Probable protein phosphatase 2C 4

Gene

GSPATT00020181001

Organism
Paramecium tetraurelia
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Enzyme with a broad specificity.By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi57Manganese 1By similarity1
Metal bindingi57Manganese 2By similarity1
Metal bindingi58Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi237Manganese 2By similarity1
Metal bindingi289Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 4 (EC:3.1.3.16)
Short name:
PP2C 4
Gene namesi
ORF Names:GSPATT00020181001
OrganismiParamecium tetraurelia
Taxonomic identifieri5888 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
Proteomesi
  • UP000000600 Componenti: Partially assembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003078311 – 301Probable protein phosphatase 2C 4Add BLAST301

Proteomic databases

PRIDEiA0DTY1

Interactioni

Protein-protein interaction databases

STRINGi412030.XP_001453895.1

Structurei

3D structure databases

ProteinModelPortaliA0DTY1
SMRiA0DTY1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 298PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST276

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
InParanoidiA0DTY1
KOiK17499
OMAiAICIMHI

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR000222 PP2C_BS
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS01032 PPM_1, 1 hit
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0DTY1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPYLSQPNK NKTTTSGEGK SIIFAASEMQ GWRNTMEDAH IHVCDLQQDL
60 70 80 90 100
SIFGVFDGHG GKEVAQFVEK HFIEELQKNK NFKDQKFEDA LRETFLKMDE
110 120 130 140 150
LLLTPEGQKE IIQIKGGDDE ASYAGCTANV ALFHKNVLYV ANAGDSRSVL
160 170 180 190 200
CRNNTNYDMS VDHKPDNYEE KSRIERAGGF VSDGRVNGNL NLSRALGDLE
210 220 230 240 250
YKRDSKLRSN EQLIIALPDI KKVELNQTDK FLLMGCDGVF ETLDHQDLLK
260 270 280 290 300
FINQKLGNQQ ITPQLLGRVA EDLLDNLIAP DTSAGTGCDN MTTLIIYLKG

K
Length:301
Mass (Da):33,666
Last modified:November 28, 2006 - v1
Checksum:iC63A00AB18150686
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT868574 Genomic DNA Translation: CAK86498.1
RefSeqiXP_001453895.1, XM_001453858.1
UniGeneiPte.2272

Genome annotation databases

EnsemblProtistsiCAK86498; CAK86498; GSPATT00020181001
GeneIDi5039680
KEGGiptm:GSPATT00020181001

Similar proteinsi

Entry informationi

Entry nameiPP2C4_PARTE
AccessioniPrimary (citable) accession number: A0DTY1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: November 28, 2006
Last modified: May 23, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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