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A0DTY1

- PP2C4_PARTE

UniProt

A0DTY1 - PP2C4_PARTE

Protein

Probable protein phosphatase 2C 4

Gene

GSPATT00020181001

Organism
Paramecium tetraurelia
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (28 Nov 2006)
      Previous versions | rss
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    Functioni

    Enzyme with a broad specificity.By similarity

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi57 – 571Manganese 1By similarity
    Metal bindingi57 – 571Manganese 2By similarity
    Metal bindingi58 – 581Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi237 – 2371Manganese 2By similarity
    Metal bindingi289 – 2891Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 4 (EC:3.1.3.16)
    Short name:
    PP2C 4
    Gene namesi
    ORF Names:GSPATT00020181001
    OrganismiParamecium tetraurelia
    Taxonomic identifieri5888 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
    ProteomesiUP000000600: Partially assembled WGS sequence

    Subcellular locationi

    Membrane By similarity; Peripheral membrane protein By similarity

    GO - Cellular componenti

    1. membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 301301Probable protein phosphatase 2C 4PRO_0000307831Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliA0DTY1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PP2C family.Curated

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0DTY1-1 [UniParc]FASTAAdd to Basket

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    MGPYLSQPNK NKTTTSGEGK SIIFAASEMQ GWRNTMEDAH IHVCDLQQDL    50
    SIFGVFDGHG GKEVAQFVEK HFIEELQKNK NFKDQKFEDA LRETFLKMDE 100
    LLLTPEGQKE IIQIKGGDDE ASYAGCTANV ALFHKNVLYV ANAGDSRSVL 150
    CRNNTNYDMS VDHKPDNYEE KSRIERAGGF VSDGRVNGNL NLSRALGDLE 200
    YKRDSKLRSN EQLIIALPDI KKVELNQTDK FLLMGCDGVF ETLDHQDLLK 250
    FINQKLGNQQ ITPQLLGRVA EDLLDNLIAP DTSAGTGCDN MTTLIIYLKG 300
    K 301
    Length:301
    Mass (Da):33,666
    Last modified:November 28, 2006 - v1
    Checksum:iC63A00AB18150686
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT868574 Genomic DNA. Translation: CAK86498.1.
    RefSeqiXP_001453895.1. XM_001453858.1.
    UniGeneiPte.2272.

    Genome annotation databases

    EnsemblProtistsiCAK86498; CAK86498; GSPATT00020181001.
    GeneIDi5039680.
    KEGGiptm:GSPATT00020181001.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT868574 Genomic DNA. Translation: CAK86498.1 .
    RefSeqi XP_001453895.1. XM_001453858.1.
    UniGenei Pte.2272.

    3D structure databases

    ProteinModelPortali A0DTY1.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi CAK86498 ; CAK86498 ; GSPATT00020181001 .
    GeneIDi 5039680.
    KEGGi ptm:GSPATT00020181001.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Stock d4-2.

    Entry informationi

    Entry nameiPP2C4_PARTE
    AccessioniPrimary (citable) accession number: A0DTY1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 23, 2007
    Last sequence update: November 28, 2006
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3