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Protein

Probable protein phosphatase 2C 6

Gene

GSPATT00019634001

Organism
Paramecium tetraurelia
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Enzyme with a broad specificity.By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi57Manganese 1By similarity1
Metal bindingi57Manganese 2By similarity1
Metal bindingi58Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi237Manganese 2By similarity1
Metal bindingi285Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 6 (EC:3.1.3.16)
Short name:
PP2C 6
Gene namesi
ORF Names:GSPATT00019634001
OrganismiParamecium tetraurelia
Taxonomic identifieri5888 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
Proteomesi
  • UP000000600 Componenti: Partially assembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003078331 – 295Probable protein phosphatase 2C 6Add BLAST295

Interactioni

Protein-protein interaction databases

STRINGi412030.XP_001453327.1

Structurei

3D structure databases

ProteinModelPortaliA0DSB3
SMRiA0DSB3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 294PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST272

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
InParanoidiA0DSB3
KOiK01090
OMAiNTERDDI

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR000222 PP2C_BS
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 2 hits
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS01032 PPM_1, 1 hit
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0DSB3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPYLSQPKT EKTSVTGQNQ VLQYAATHMQ GWRNTMEDAH ISDLNIEPDV
60 70 80 90 100
HLFAVFDGHG GSEVAIFAER HFREELMKNK NYQQKNYEKA LTETFFKIDK
110 120 130 140 150
MLQEPSGLDE LNKIRGVTDE ASLAGCTANV ALIVGKTLYV ANAGDSRSFL
160 170 180 190 200
NRDGKPFDMS KDHKPDDEQE KKRIERAGGF VSDGRVNGNL SLSRALGDLE
210 220 230 240 250
YKKDNRFKPE EQIITALPDV KVTQLSAADK FLLMGCDGVF ETWDHQQILN
260 270 280 290
FINSELKNTQ NLQKAAEKLL DQLLAKDTSL GTGCDNMTCI LIQFK
Length:295
Mass (Da):33,111
Last modified:November 28, 2006 - v1
Checksum:i38665E7161821015
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT868552 Genomic DNA Translation: CAK85930.1
RefSeqiXP_001453327.1, XM_001453290.1
UniGeneiPte.3730

Genome annotation databases

EnsemblProtistsiCAK85930; CAK85930; GSPATT00019634001
GeneIDi5039112
KEGGiptm:GSPATT00019634001

Similar proteinsi

Entry informationi

Entry nameiPP2C6_PARTE
AccessioniPrimary (citable) accession number: A0DSB3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: November 28, 2006
Last modified: March 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health