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A0DSB3

- PP2C6_PARTE

UniProt

A0DSB3 - PP2C6_PARTE

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Protein

Probable protein phosphatase 2C 6

Gene
GSPATT00019634001
Organism
Paramecium tetraurelia
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Enzyme with a broad specificity By similarity.

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi57 – 571Manganese 1 By similarity
Metal bindingi57 – 571Manganese 2 By similarity
Metal bindingi58 – 581Manganese 1; via carbonyl oxygen By similarity
Metal bindingi237 – 2371Manganese 2 By similarity
Metal bindingi285 – 2851Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 6 (EC:3.1.3.16)
Short name:
PP2C 6
Gene namesi
ORF Names:GSPATT00019634001
OrganismiParamecium tetraurelia
Taxonomic identifieri5888 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
ProteomesiUP000000600: Partially assembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 295295Probable protein phosphatase 2C 6PRO_0000307833Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliA0DSB3.

Family & Domainsi

Sequence similaritiesi

Belongs to the PP2C family.

Phylogenomic databases

KOiK01090.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0DSB3-1 [UniParc]FASTAAdd to Basket

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MGPYLSQPKT EKTSVTGQNQ VLQYAATHMQ GWRNTMEDAH ISDLNIEPDV    50
HLFAVFDGHG GSEVAIFAER HFREELMKNK NYQQKNYEKA LTETFFKIDK 100
MLQEPSGLDE LNKIRGVTDE ASLAGCTANV ALIVGKTLYV ANAGDSRSFL 150
NRDGKPFDMS KDHKPDDEQE KKRIERAGGF VSDGRVNGNL SLSRALGDLE 200
YKKDNRFKPE EQIITALPDV KVTQLSAADK FLLMGCDGVF ETWDHQQILN 250
FINSELKNTQ NLQKAAEKLL DQLLAKDTSL GTGCDNMTCI LIQFK 295
Length:295
Mass (Da):33,111
Last modified:November 28, 2006 - v1
Checksum:i38665E7161821015
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT868552 Genomic DNA. Translation: CAK85930.1.
RefSeqiXP_001453327.1. XM_001453290.1.
UniGeneiPte.3730.

Genome annotation databases

EnsemblProtistsiCAK85930; CAK85930; GSPATT00019634001.
GeneIDi5039112.
KEGGiptm:GSPATT00019634001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT868552 Genomic DNA. Translation: CAK85930.1 .
RefSeqi XP_001453327.1. XM_001453290.1.
UniGenei Pte.3730.

3D structure databases

ProteinModelPortali A0DSB3.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi CAK85930 ; CAK85930 ; GSPATT00019634001 .
GeneIDi 5039112.
KEGGi ptm:GSPATT00019634001.

Phylogenomic databases

KOi K01090.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Stock d4-2.

Entry informationi

Entry nameiPP2C6_PARTE
AccessioniPrimary (citable) accession number: A0DSB3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: November 28, 2006
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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