Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A0DJ90

- PPX2_PARTE

UniProt

A0DJ90 - PPX2_PARTE

Protein

Serine/threonine-protein phosphatase PP-X homolog 2

Gene

Ppx2

Organism
Paramecium tetraurelia
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (28 Nov 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi51 – 511Manganese 1By similarity
    Metal bindingi53 – 531Manganese 1By similarity
    Metal bindingi79 – 791Manganese 1By similarity
    Metal bindingi79 – 791Manganese 2By similarity
    Metal bindingi111 – 1111Manganese 2By similarity
    Active sitei112 – 1121Proton donorBy similarity
    Metal bindingi161 – 1611Manganese 2By similarity
    Metal bindingi235 – 2351Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein phosphatase PP-X homolog 2 (EC:3.1.3.16)
    Gene namesi
    Name:Ppx2
    ORF Names:GSPATT00017464001
    OrganismiParamecium tetraurelia
    Taxonomic identifieri5888 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
    ProteomesiUP000000600: Partially assembled WGS sequence

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 303303Serine/threonine-protein phosphatase PP-X homolog 2PRO_0000308174Add
    BLAST

    Proteomic databases

    PRIDEiA0DJ90.

    Structurei

    3D structure databases

    ProteinModelPortaliA0DJ90.
    SMRiA0DJ90. Positions 3-303.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.60.21.10. 1 hit.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    [Graphical view]
    PRINTSiPR00114. STPHPHTASE.
    SMARTiSM00156. PP2Ac. 1 hit.
    [Graphical view]
    SUPFAMiSSF56300. SSF56300. 1 hit.
    PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0DJ90-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDIDQWIET LKNGENLKET DVKILCNKAK DILNNEDNVI RVEAPVTICG    50
    DIHGQFQDLM ELFKVGGDVP ETNYLFLGDF VDRGYNSVET FLLLLALKVR 100
    YPDQITLIRG NHESRQITQV YGFYDECLRK YSTLNVWKYC TEVFDYLALA 150
    AVVNDSIFCV HGGLSPYIKT IDEIRIINRK QEVPHEGVMC DLMWSDPDEI 200
    EGWSQSARGA GFVFGADVVK EFNRRNGISL ICRAHQLAME GFKLMFDNSL 250
    VTVWSAPNYC YRCGNVASIL ELDENLKKYY KLFEAAPTDR ASNSKKTIAD 300
    YFL 303
    Length:303
    Mass (Da):34,643
    Last modified:November 28, 2006 - v1
    Checksum:i1A1C31BE0EB45BE5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT868452 Genomic DNA. Translation: CAK83107.1.
    RefSeqiXP_001450504.1. XM_001450467.1.
    UniGeneiPte.4241.

    Genome annotation databases

    EnsemblProtistsiCAK83107; CAK83107; GSPATT00017464001.
    GeneIDi5036289.
    KEGGiptm:GSPATT00017464001.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT868452 Genomic DNA. Translation: CAK83107.1 .
    RefSeqi XP_001450504.1. XM_001450467.1.
    UniGenei Pte.4241.

    3D structure databases

    ProteinModelPortali A0DJ90.
    SMRi A0DJ90. Positions 3-303.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi A0DJ90.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi CAK83107 ; CAK83107 ; GSPATT00017464001 .
    GeneIDi 5036289.
    KEGGi ptm:GSPATT00017464001.

    Family and domain databases

    Gene3Di 3.60.21.10. 1 hit.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    [Graphical view ]
    PRINTSi PR00114. STPHPHTASE.
    SMARTi SM00156. PP2Ac. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56300. SSF56300. 1 hit.
    PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Stock d4-2.

    Entry informationi

    Entry nameiPPX2_PARTE
    AccessioniPrimary (citable) accession number: A0DJ90
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 23, 2007
    Last sequence update: November 28, 2006
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3