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A0DJ90

- PPX2_PARTE

UniProt

A0DJ90 - PPX2_PARTE

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Protein

Serine/threonine-protein phosphatase PP-X homolog 2

Gene

Ppx2

Organism
Paramecium tetraurelia
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi51 – 511Manganese 1By similarity
Metal bindingi53 – 531Manganese 1By similarity
Metal bindingi79 – 791Manganese 1By similarity
Metal bindingi79 – 791Manganese 2By similarity
Metal bindingi111 – 1111Manganese 2By similarity
Active sitei112 – 1121Proton donorBy similarity
Metal bindingi161 – 1611Manganese 2By similarity
Metal bindingi235 – 2351Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP-X homolog 2 (EC:3.1.3.16)
Gene namesi
Name:Ppx2
ORF Names:GSPATT00017464001
OrganismiParamecium tetraurelia
Taxonomic identifieri5888 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
ProteomesiUP000000600: Partially assembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Serine/threonine-protein phosphatase PP-X homolog 2PRO_0000308174Add
BLAST

Proteomic databases

PRIDEiA0DJ90.

Structurei

3D structure databases

ProteinModelPortaliA0DJ90.
SMRiA0DJ90. Positions 3-303.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

InParanoidiA0DJ90.

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0DJ90-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDIDQWIET LKNGENLKET DVKILCNKAK DILNNEDNVI RVEAPVTICG
60 70 80 90 100
DIHGQFQDLM ELFKVGGDVP ETNYLFLGDF VDRGYNSVET FLLLLALKVR
110 120 130 140 150
YPDQITLIRG NHESRQITQV YGFYDECLRK YSTLNVWKYC TEVFDYLALA
160 170 180 190 200
AVVNDSIFCV HGGLSPYIKT IDEIRIINRK QEVPHEGVMC DLMWSDPDEI
210 220 230 240 250
EGWSQSARGA GFVFGADVVK EFNRRNGISL ICRAHQLAME GFKLMFDNSL
260 270 280 290 300
VTVWSAPNYC YRCGNVASIL ELDENLKKYY KLFEAAPTDR ASNSKKTIAD

YFL
Length:303
Mass (Da):34,643
Last modified:November 28, 2006 - v1
Checksum:i1A1C31BE0EB45BE5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT868452 Genomic DNA. Translation: CAK83107.1.
RefSeqiXP_001450504.1. XM_001450467.1.
UniGeneiPte.4241.

Genome annotation databases

EnsemblProtistsiCAK83107; CAK83107; GSPATT00017464001.
GeneIDi5036289.
KEGGiptm:GSPATT00017464001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT868452 Genomic DNA. Translation: CAK83107.1 .
RefSeqi XP_001450504.1. XM_001450467.1.
UniGenei Pte.4241.

3D structure databases

ProteinModelPortali A0DJ90.
SMRi A0DJ90. Positions 3-303.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi A0DJ90.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi CAK83107 ; CAK83107 ; GSPATT00017464001 .
GeneIDi 5036289.
KEGGi ptm:GSPATT00017464001.

Phylogenomic databases

InParanoidi A0DJ90.

Family and domain databases

Gene3Di 3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
[Graphical view ]
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Stock d4-2.

Entry informationi

Entry nameiPPX2_PARTE
AccessioniPrimary (citable) accession number: A0DJ90
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: November 28, 2006
Last modified: October 29, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3