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A0CUB5

- PP2C5_PARTE

UniProt

A0CUB5 - PP2C5_PARTE

Protein

Probable protein phosphatase 2C 5

Gene

GSPATT00010582001

Organism
Paramecium tetraurelia
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (28 Nov 2006)
      Previous versions | rss
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    Functioni

    Enzyme with a broad specificity.By similarity

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi57 – 571Manganese 1By similarity
    Metal bindingi57 – 571Manganese 2By similarity
    Metal bindingi58 – 581Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi237 – 2371Manganese 2By similarity
    Metal bindingi285 – 2851Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 5 (EC:3.1.3.16)
    Short name:
    PP2C 5
    Gene namesi
    ORF Names:GSPATT00010582001
    OrganismiParamecium tetraurelia
    Taxonomic identifieri5888 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
    ProteomesiUP000000600: Partially assembled WGS sequence

    Subcellular locationi

    Membrane By similarity; Peripheral membrane protein By similarity

    GO - Cellular componenti

    1. membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 295295Probable protein phosphatase 2C 5PRO_0000307832Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliA0CUB5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PP2C family.Curated

    Phylogenomic databases

    KOiK17499.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0CUB5-1 [UniParc]FASTAAdd to Basket

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    MGPYLSQPKT EKSTVTGQNQ VFQYAATHMQ GWRNTMEDAH ISDMNIEPDV    50
    HLFAVFDGHG GSEVAIFAER HFREELMKNK NYQQKNYEKA LTETFFKIDK 100
    MLQEPSGQDE LNKIRGVNDE TSLAGCTANV ALIVGKTLYV ANAGDSRSFL 150
    NRDGKPFDMS KDHKPDDDQE KKRIERAGGF VSDGRANGNL SLSRALGDLE 200
    YKKDSRFKPE EQIISALPDV KVTQLTASDK FLLMGCDGVF ETWDHQQILN 250
    FVNQELKSSQ NLQKATEKLL DQLLAKDTSL GTGCDNMTCI LVLFK 295
    Length:295
    Mass (Da):33,155
    Last modified:November 28, 2006 - v1
    Checksum:i53C6D72891A090EC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT868185 Genomic DNA. Translation: CAK74382.1.
    RefSeqiXP_001441779.1. XM_001441742.1.
    UniGeneiPte.257.

    Genome annotation databases

    EnsemblProtistsiCAK74382; CAK74382; GSPATT00010582001.
    GeneIDi5027564.
    KEGGiptm:GSPATT00010582001.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT868185 Genomic DNA. Translation: CAK74382.1 .
    RefSeqi XP_001441779.1. XM_001441742.1.
    UniGenei Pte.257.

    3D structure databases

    ProteinModelPortali A0CUB5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi CAK74382 ; CAK74382 ; GSPATT00010582001 .
    GeneIDi 5027564.
    KEGGi ptm:GSPATT00010582001.

    Phylogenomic databases

    KOi K17499.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Stock d4-2.

    Entry informationi

    Entry nameiPP2C5_PARTE
    AccessioniPrimary (citable) accession number: A0CUB5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 23, 2007
    Last sequence update: November 28, 2006
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3