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Protein

Thymidine kinase

Gene

GSPATT00036470001

Organism
Paramecium tetraurelia
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
ORF Names:GSPATT00036470001Imported
OrganismiParamecium tetraureliaImported
Taxonomic identifieri5888 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
ProteomesiUP000000600: Partially assembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliA0CA73.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

InParanoidiA0CA73.
KOiK00857.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0CA73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFTGTISVIY GPMFSGKTSE LMRLVKRFTI SERKCAVLNY ANDNRYSDDQ
60 70 80 90 100
CISSHDKQYL KAIKVTKLFD AFEKCKDYDV VAIDEGQFFC DIVEFSEAMA
110 120 130 140 150
NLGKIVIVAA LDGTFDRKPF RNILSLIPLA ERITKLTAVC WFCKKENASF
160 170 180 190 200
TKRTVQSQEI ELIGGEDCYK PACRACFNLT EDKFEKHTLS QIPVYSNDER

LFGQQNLIC
Length:209
Mass (Da):23,875
Last modified:November 28, 2006 - v1
Checksum:i30982FEC6BF17FCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT868053 Genomic DNA. Translation: CAK67690.1.
RefSeqiXP_001435087.1. XM_001435050.1.

Genome annotation databases

EnsemblProtistsiCAK67690; CAK67690; GSPATT00036470001.
GeneIDi5020872.
KEGGiptm:GSPATT00036470001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT868053 Genomic DNA. Translation: CAK67690.1.
RefSeqiXP_001435087.1. XM_001435050.1.

3D structure databases

ProteinModelPortaliA0CA73.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCAK67690; CAK67690; GSPATT00036470001.
GeneIDi5020872.
KEGGiptm:GSPATT00036470001.

Phylogenomic databases

InParanoidiA0CA73.
KOiK00857.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Stock d4-2Imported.

Entry informationi

Entry nameiA0CA73_PARTE
AccessioniPrimary (citable) accession number: A0CA73
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2006
Last sequence update: November 28, 2006
Last modified: January 7, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.