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A0C993

- A0C993_PARTE

UniProt

A0C993 - A0C993_PARTE

Protein

Histone deacetylase

Gene

GSPATT00006666001

Organism
Paramecium tetraurelia
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (28 Nov 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

    GO - Molecular functioni

    1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
    2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
    3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
    4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
    Gene namesi
    ORF Names:GSPATT00006666001Imported
    OrganismiParamecium tetraureliaImported
    Taxonomic identifieri5888 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
    ProteomesiUP000000600: Partially assembled WGS sequence

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliA0C993.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    KOiK06067.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSiPR01270. HDASUPER.
    PR01271. HISDACETLASE.

    Sequencei

    Sequence statusi: Complete.

    A0C993-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNLFKQKVTY YYDEEFGTFN YSTTHPMKPL RVAITDDLVG HYGLKQYMNC    50
    IVRCINLVDE DVLTQFHSEE YINLIKIITP ENKCQHEDQL YRFNFMEDCP 100
    VLDRLFDFCL CQTSGSVGAA CVIADQKSNI AINWSGGLHH AKQSEASGFC 150
    YVNDCVLGIL ELLKTYQRVL YIDIDIHHGD GVEEAFYLTD RVMTCSFHKF 200
    KEYFPGTGHI DDIGHDKGKY YAVNFPLNEG LNDDSIQLIF KPVIDSIMEN 250
    FRPDVVMLQG GTDSLSGDRL GCFNLSIKGH GSCTEYLKKF NVPIIMVGGG 300
    GYTLRNVPRC WTYETSLALN VPIPDNIPDE SDYKIYFGPE YKLHLPISNM 350
    EEQNSKEYLE KNISQRIQNK FEPGCAQIDH YAIGKESRQK IDYQELFSSY 400
    NDKREEMQLE QNQDQQE 417
    Length:417
    Mass (Da):48,016
    Last modified:November 28, 2006 - v1
    Checksum:i99A8C2AE48F42DA9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT868052 Genomic DNA. Translation: CAK67360.1.
    RefSeqiXP_001434757.1. XM_001434720.1.

    Genome annotation databases

    EnsemblProtistsiCAK67360; CAK67360; GSPATT00006666001.
    GeneIDi5020542.
    KEGGiptm:GSPATT00006666001.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT868052 Genomic DNA. Translation: CAK67360.1 .
    RefSeqi XP_001434757.1. XM_001434720.1.

    3D structure databases

    ProteinModelPortali A0C993.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi CAK67360 ; CAK67360 ; GSPATT00006666001 .
    GeneIDi 5020542.
    KEGGi ptm:GSPATT00006666001.

    Phylogenomic databases

    KOi K06067.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSi PR01270. HDASUPER.
    PR01271. HISDACETLASE.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Stock d4-2Imported.

    Entry informationi

    Entry nameiA0C993_PARTE
    AccessioniPrimary (citable) accession number: A0C993
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 28, 2006
    Last sequence update: November 28, 2006
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3