ID   A0C8R8_PARTE            Unreviewed;       366 AA.
AC   A0C8R8;
DT   28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2006, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   SubName: Full=Chromosome undetermined scaffold_159, whole genome shotgun sequence {ECO:0000313|EMBL:CAK67185.1};
GN   ORFNames=GSPATT00036320001 {ECO:0000313|EMBL:CAK67185.1};
OS   Paramecium tetraurelia.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX   NCBI_TaxID=5888 {ECO:0000313|EMBL:CAK67185.1, ECO:0000313|Proteomes:UP000000600};
RN   [1] {ECO:0000313|EMBL:CAK67185.1, ECO:0000313|Proteomes:UP000000600}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Stock d4-2 {ECO:0000313|EMBL:CAK67185.1,
RC   ECO:0000313|Proteomes:UP000000600};
RX   PubMed=17086204; DOI=10.1038/nature05230;
RG   Genoscope;
RA   Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA   Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA   Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA   Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA   Le Moue A., Lepere C., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA   Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA   Weissenbach J., Scarpelli C., Schachter V., Sperling L., Meyer E.,
RA   Cohen J., Wincker P.;
RT   "Global trends of whole-genome duplications revealed by the ciliate
RT   Paramecium tetraurelia.";
RL   Nature 444:171-178(2006).
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DR   EMBL; CT868051; CAK67185.1; -; Genomic_DNA.
DR   RefSeq; XP_001434582.1; XM_001434545.1.
DR   AlphaFoldDB; A0C8R8; -.
DR   STRING; 5888.A0C8R8; -.
DR   EnsemblProtists; CAK67185; CAK67185; GSPATT00036320001.
DR   GeneID; 5020367; -.
DR   KEGG; ptm:GSPATT00036320001; -.
DR   eggNOG; KOG1344; Eukaryota.
DR   HOGENOM; CLU_007727_1_1_1; -.
DR   InParanoid; A0C8R8; -.
DR   OMA; DESYNIT; -.
DR   Proteomes; UP000000600; Partially assembled WGS sequence.
DR   GO; GO:0000118; C:histone deacetylase complex; IBA:GO_Central.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004407; F:histone deacetylase activity; IBA:GO_Central.
DR   CDD; cd09993; HDAC_classIV; 1.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR   InterPro; IPR044150; HDAC_classIV.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625:SF33; HISTONE DEACETYLASE 11; 1.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000600};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          157..356
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
SQ   SEQUENCE   366 AA;  41647 MW;  240BFC736556DD1F CRC64;
     MQLYTIIDWF FTIGSLVLAI LLGVYVNGAA CLLGVFLYFI YPFIMEFSYN LLSVREEICI
     RNMPEIPIVY DESYNITACG IEKWHPFDSC KYGNVYRQIR QQVKGSHFTP KMLSRGTFLY
     LGMSKWYLLK MCYSAYASTL IELPVFFLPG AFLRSCLLDS MLLATSGSIQ AAKLALEKGW
     AINLSGGYHH ASLNRGGGFC IYPDITLVVN YLKRCCNLKK IVIVDLDAHQ GNGYERDFLN
     DSSVYIIDFY NSYIYPGDHI AEQAISCFEH IDKDTSDQQY IKTLQRDLET HLKDDMEFLI
     YNAGTDIMAG DPLGHCCISA AGIKRRDEVV FKWAQHKKIP FLMLLSGGYQ KENTFAIGES
     ILQLIT
//