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A0C1E4

- PPX3_PARTE

UniProt

A0C1E4 - PPX3_PARTE

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Protein
Serine/threonine-protein phosphatase PP-X homolog 3
Gene
Ppx3, GSPATT00034087001
Organism
Paramecium tetraurelia
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi53 – 531Manganese 1 By similarity
Metal bindingi55 – 551Manganese 1 By similarity
Metal bindingi81 – 811Manganese 1 By similarity
Metal bindingi81 – 811Manganese 2 By similarity
Metal bindingi113 – 1131Manganese 2 By similarity
Active sitei114 – 1141Proton donor By similarity
Metal bindingi163 – 1631Manganese 2 By similarity
Metal bindingi237 – 2371Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP-X homolog 3 (EC:3.1.3.16)
Gene namesi
Name:Ppx3
ORF Names:GSPATT00034087001
OrganismiParamecium tetraurelia
Taxonomic identifieri5888 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
ProteomesiUP000000600: Partially assembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 305305Serine/threonine-protein phosphatase PP-X homolog 3
PRO_0000308175Add
BLAST

Proteomic databases

PRIDEiA0C1E4.

Structurei

3D structure databases

ProteinModelPortaliA0C1E4.
SMRiA0C1E4. Positions 5-305.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0C1E4-1 [UniParc]FASTAAdd to Basket

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MSQSDLDRQI AQLRNCENIT EGEVKALCTK AREILVEESN VQRVDAPVTI    50
CGDIHGQFFD LMELFKVGGD CPDTNYLFLG DFVDRGFNSV ETFLLLLALK 100
VRYPDRITLI RGNHESRQIT QVYGFYDECL RKYGSLNVWR YCTDIFDYLS 150
LAAVIEEKIF CVHGGLSPSI KTMDDIRAID RKQEVPHDGA MCDLMWSDPD 200
EIEGWNLSPR GAGYLFGGDV VDDFNRKNNI ELICRAHQLV MEGYRVMFNE 250
QLVTVWSAPN YCYRCGNVAS ILELDENLTK QYKIFEAAQE NKGLPAKKPI 300
PDYFL 305
Length:305
Mass (Da):34,905
Last modified:November 28, 2006 - v1
Checksum:iA5305863340862C3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT868032 Genomic DNA. Translation: CAK64611.1.
RefSeqiXP_001432009.1. XM_001431972.1.

Genome annotation databases

EnsemblProtistsiCAK64611; CAK64611; GSPATT00034087001.
GeneIDi5017793.
KEGGiptm:GSPATT00034087001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT868032 Genomic DNA. Translation: CAK64611.1 .
RefSeqi XP_001432009.1. XM_001431972.1.

3D structure databases

ProteinModelPortali A0C1E4.
SMRi A0C1E4. Positions 5-305.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi A0C1E4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi CAK64611 ; CAK64611 ; GSPATT00034087001 .
GeneIDi 5017793.
KEGGi ptm:GSPATT00034087001.

Family and domain databases

Gene3Di 3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
[Graphical view ]
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Stock d4-2.

Entry informationi

Entry nameiPPX3_PARTE
AccessioniPrimary (citable) accession number: A0C1E4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: November 28, 2006
Last modified: June 11, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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