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Protein

Probable tRNA pseudouridine synthase B

Gene

truB

Organism
Methanosaeta thermophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) (Methanothrix thermophila)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei62NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotation, LyaseImported
Biological processtRNA processingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Mthe_1702Imported
OrganismiMethanosaeta thermophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) (Methanothrix thermophila)Imported
Taxonomic identifieri349307 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosaetaceaeMethanosaeta
Proteomesi
  • UP000000674 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi349307.Mthe_1702.

Structurei

3D structure databases

ProteinModelPortaliA0B9U4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini230 – 305PUAInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00987. Archaea.
COG0130. LUCA.
HOGENOMiHOG000231224.
KOiK11131.
OMAiIYQRPPL.
OrthoDBiPOG093Z08NS.

Family and domain databases

Gene3Di2.30.130.10. 1 hit.
HAMAPiMF_01081. TruB_arch. 1 hit.
InterProiView protein in InterPro
IPR012960. Dyskerin-like.
IPR020103. PsdUridine_synth_cat_dom_sf.
IPR002501. PsdUridine_synth_N.
IPR002478. PUA.
IPR015947. PUA-like_sf.
IPR036974. PUA_sf.
IPR004802. tRNA_PsdUridine_synth_B_fam.
IPR026326. TruB_arch.
IPR032819. TruB_C.
IPR004521. Uncharacterised_CHP00451.
PANTHERiPTHR23127. PTHR23127. 1 hit.
PfamiView protein in Pfam
PF08068. DKCLD. 1 hit.
PF01472. PUA. 1 hit.
PF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
SMARTiView protein in SMART
SM01136. DKCLD. 1 hit.
SM00359. PUA. 1 hit.
SUPFAMiSSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR00425. CBF5. 1 hit.
TIGR00451. unchar_dom_2. 1 hit.
PROSITEiView protein in PROSITE
PS50890. PUA. 1 hit.

Sequencei

Sequence statusi: Complete.

A0B9U4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRREGSTNSS YGCFPDRRPL QEHLRLGAIN LDKPSGPTSH EVVAWVKRIL
60 70 80 90 100
GLEKAGHSGT LDPRVTGILP VLTGDATRVV EFLLTAGKEY VCLMRTHEQV
110 120 130 140 150
PRKKILEVCE EFSGEIYQRP PLKSSVARNL RTRKIYYIDV LEIEGQRVLM
160 170 180 190 200
KVGCEAGTYI RKLCYDMGLA LGCGANMEEL RRTKAGPFAE DETLVTLHNL
210 220 230 240 250
KDAYEIWRES GDESALRRAV LPVERALRHL PGLVISDNAV DAICHGAPLA
260 270 280 290 300
APGLLSLETD INKGDFVVIY TLKGEAVAIG RAKLSSDEMM VAKSGIVAST
310 320
ERVIMDPGVY PRRWKHSAEV V
Length:321
Mass (Da):35,520
Last modified:November 28, 2006 - v1
Checksum:iD15477BBEAC78DD5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000477 Genomic DNA. Translation: ABK15468.1.

Genome annotation databases

EnsemblBacteriaiABK15468; ABK15468; Mthe_1702.
KEGGimtp:Mthe_1702.

Similar proteinsi

Entry informationi

Entry nameiA0B9U4_METTP
AccessioniPrimary (citable) accession number: A0B9U4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2006
Last sequence update: November 28, 2006
Last modified: November 22, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported