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A0B9M2 (UPPP_METTP) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Mthe_1629
OrganismMethanosaeta thermophila (strain DSM 6194 / PT) (Methanothrix thermophila (strain DSM 6194 / PT)) [Complete proteome] [HAMAP]
Taxonomic identifier349307 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosaetaceaeMethanosaeta

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Sequence similarities

Belongs to the UppP family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processdephosphorylation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionundecaprenyl-diphosphatase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 256256Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000290784

Regions

Transmembrane39 – 5921Helical; Potential
Transmembrane77 – 9721Helical; Potential
Transmembrane101 – 12121Helical; Potential
Transmembrane135 – 15521Helical; Potential
Transmembrane176 – 19621Helical; Potential
Transmembrane206 – 22621Helical; Potential
Transmembrane233 – 25321Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
A0B9M2 [UniParc].

Last modified November 28, 2006. Version 1.
Checksum: 6CC5C9309CA59BFF

FASTA25627,511
        10         20         30         40         50         60 
MDALQALVLG ALQGITEWLP VSSEGQTMLA MISWLGMRPT DALSCSIFLH TGTMLAVLVR 

        70         80         90        100        110        120 
FRSRLLGMLN TESKLMRTVI VATLFTGITG VPLYMLFRDR FTGGEQATLL IGSLLIATGL 

       130        140        150        160        170        180 
MLRLRSSSTK DMEEISTKDM VLLGLAQGFS ILPGVSRSGT TLTVLLMRGV KQDDALMVSF 

       190        200        210        220        230        240 
IISVPAVLGA IALDCLAGSP LSIRSLPGAV MLASSFITGY ATMDVLMRFS RNVSFSWFCI 

       250 
TMGMITLALT ALPEVQ 

« Hide

References

[1]"Complete sequence of Methanosaeta thermophila PT."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Smith K.S., Ingram-Smith C., Richardson P.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 6194 / PT.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000477 Genomic DNA. Translation: ABK15396.1.
RefSeqYP_844036.1. NC_008553.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING349307.Mthe_1629.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK15396; ABK15396; Mthe_1629.
GeneID4462206.
KEGGmtp:Mthe_1629.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
OMAWEFLATG.
ProtClustDBCLSK569097.

Enzyme and pathway databases

BioCycMMET349307:GHKI-1679-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_METTP
AccessionPrimary (citable) accession number: A0B9M2
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: November 28, 2006
Last modified: February 19, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families