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A0B9M2

- UPPP_METTP

UniProt

A0B9M2 - UPPP_METTP

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Protein

Undecaprenyl-diphosphatase

Gene

uppP

Organism
Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrix thermophila (strain DSM 6194 / PT))
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).UniRule annotation

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.UniRule annotation

GO - Molecular functioni

  1. undecaprenyl-diphosphatase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciMMET349307:GHKI-1679-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Undecaprenyl-diphosphataseUniRule annotation (EC:3.6.1.27UniRule annotation)
Alternative name(s):
Undecaprenyl pyrophosphate phosphataseUniRule annotation
Gene namesi
Name:uppPUniRule annotation
Ordered Locus Names:Mthe_1629
OrganismiMethanosaeta thermophila (strain DSM 6194 / PT) (Methanothrix thermophila (strain DSM 6194 / PT))
Taxonomic identifieri349307 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosaetaceaeMethanosaeta
ProteomesiUP000000674: Chromosome

Subcellular locationi

Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 256256Undecaprenyl-diphosphatasePRO_0000290784Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi349307.Mthe_1629.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei39 – 5921HelicalUniRule annotationAdd
BLAST
Transmembranei77 – 9721HelicalUniRule annotationAdd
BLAST
Transmembranei101 – 12121HelicalUniRule annotationAdd
BLAST
Transmembranei135 – 15521HelicalUniRule annotationAdd
BLAST
Transmembranei176 – 19621HelicalUniRule annotationAdd
BLAST
Transmembranei206 – 22621HelicalUniRule annotationAdd
BLAST
Transmembranei233 – 25321HelicalUniRule annotationAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the UppP family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1968.
HOGENOMiHOG000218357.
OMAiIEGPFRD.

Family and domain databases

HAMAPiMF_01006. Undec_diphosphatase.
InterProiIPR003824. UppP.
[Graphical view]
PfamiPF02673. BacA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0B9M2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDALQALVLG ALQGITEWLP VSSEGQTMLA MISWLGMRPT DALSCSIFLH
60 70 80 90 100
TGTMLAVLVR FRSRLLGMLN TESKLMRTVI VATLFTGITG VPLYMLFRDR
110 120 130 140 150
FTGGEQATLL IGSLLIATGL MLRLRSSSTK DMEEISTKDM VLLGLAQGFS
160 170 180 190 200
ILPGVSRSGT TLTVLLMRGV KQDDALMVSF IISVPAVLGA IALDCLAGSP
210 220 230 240 250
LSIRSLPGAV MLASSFITGY ATMDVLMRFS RNVSFSWFCI TMGMITLALT

ALPEVQ
Length:256
Mass (Da):27,511
Last modified:November 28, 2006 - v1
Checksum:i6CC5C9309CA59BFF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000477 Genomic DNA. Translation: ABK15396.1.
RefSeqiWP_011696774.1. NC_008553.1.
YP_844036.1. NC_008553.1.

Genome annotation databases

EnsemblBacteriaiABK15396; ABK15396; Mthe_1629.
GeneIDi4462206.
KEGGimtp:Mthe_1629.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000477 Genomic DNA. Translation: ABK15396.1 .
RefSeqi WP_011696774.1. NC_008553.1.
YP_844036.1. NC_008553.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 349307.Mthe_1629.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK15396 ; ABK15396 ; Mthe_1629 .
GeneIDi 4462206.
KEGGi mtp:Mthe_1629.

Phylogenomic databases

eggNOGi COG1968.
HOGENOMi HOG000218357.
OMAi IEGPFRD.

Enzyme and pathway databases

BioCyci MMET349307:GHKI-1679-MONOMER.

Family and domain databases

HAMAPi MF_01006. Undec_diphosphatase.
InterProi IPR003824. UppP.
[Graphical view ]
Pfami PF02673. BacA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 6194 / PT.

Entry informationi

Entry nameiUPPP_METTP
AccessioniPrimary (citable) accession number: A0B9M2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: November 28, 2006
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3