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Protein

Putative ribose 1,5-bisphosphate isomerase

Gene

Mthe_1121

Organism
Methanosaeta thermophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) (Methanothrix thermophila)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the conversion of ribose 1,5-bisphosphate to ribulose 1,5-bisphosphate (RuBP), the CO2 acceptor and substrate for RubisCO.UniRule annotation

Catalytic activityi

Alpha-D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate.UniRule annotation

Cofactori

NAD+UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi27 – 5529NADUniRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciMMET349307:GHKI-1154-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ribose 1,5-bisphosphate isomeraseUniRule annotation (EC:5.3.1.29UniRule annotation)
Alternative name(s):
Ribulose 1,5-bisphosphate synthaseUniRule annotation
Short name:
RuBP synthaseUniRule annotation
Gene namesi
Ordered Locus Names:Mthe_1121
OrganismiMethanosaeta thermophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) (Methanothrix thermophila)
Taxonomic identifieri349307 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosaetaceaeMethanosaeta
Proteomesi
  • UP000000674 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 262262Putative ribose 1,5-bisphosphate isomerasePRO_0000302884Add
BLAST

Proteomic databases

PRIDEiA0B880.

Interactioni

Subunit structurei

Homohexamer.UniRule annotation

Protein-protein interaction databases

STRINGi349307.Mthe_1121.

Structurei

3D structure databases

ProteinModelPortaliA0B880.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the THI4 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00574. Archaea.
COG1635. LUCA.
HOGENOMiHOG000106048.
KOiK03146.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00304. Thi4.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR002922. Thi4_fam.
IPR022828. Thi4_putative.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR00292. TIGR00292. 1 hit.

Sequencei

Sequence statusi: Complete.

A0B880-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALDEVKITR AIVESYLESF LKCTDVDVAL VGAGPANLVA AKRLAEADVR
60 70 80 90 100
VVLFEKRLSV GGGLWGGGMM FPRIVVQKEA CRILDEYDIW YREFEEGYYV
110 120 130 140 150
ADSIEVVAKL TAGAIDAGAE LINLVSVEDV MIREGDRIVG LVINWTAADM
160 170 180 190 200
AGIHVDPLAI RARVVIDGTG HDAAVCRVVQ KKIPGAIVGE SGVIGEKPMW
210 220 230 240 250
AALGEKIVVD ATREVYPGLI VAGMAATTVA AGPRMGPIFG GMLLSGEKAA
260
SIALEKLAQS VD
Length:262
Mass (Da):27,766
Last modified:September 11, 2007 - v2
Checksum:i022B4E14E7A9BE5C
GO

Sequence cautioni

The sequence ABK14904.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000477 Genomic DNA. Translation: ABK14904.1. Different initiation.

Genome annotation databases

EnsemblBacteriaiABK14904; ABK14904; Mthe_1121.
KEGGimtp:Mthe_1121.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000477 Genomic DNA. Translation: ABK14904.1. Different initiation.

3D structure databases

ProteinModelPortaliA0B880.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi349307.Mthe_1121.

Proteomic databases

PRIDEiA0B880.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK14904; ABK14904; Mthe_1121.
KEGGimtp:Mthe_1121.

Phylogenomic databases

eggNOGiarCOG00574. Archaea.
COG1635. LUCA.
HOGENOMiHOG000106048.
KOiK03146.

Enzyme and pathway databases

BioCyciMMET349307:GHKI-1154-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00304. Thi4.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR002922. Thi4_fam.
IPR022828. Thi4_putative.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR00292. TIGR00292. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 6194 / JCM 14653 / NBRC 101360 / PT.

Entry informationi

Entry nameiRUBPS_METTP
AccessioniPrimary (citable) accession number: A0B880
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: January 20, 2016
This is version 54 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.