A0B7F5 (A0B7F5_METTP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361
Short name=Poly(P)/ATP NAD kinase HAMAP MF_00361
EC=2.7.1.23 HAMAP MF_00361

Gene names

Name:	ppnK HAMAP MF_00361
Ordered Locus Names:	Mthe_0840

Organism

Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrix thermophila (strain DSM 6194 / PT)) [Complete proteome] [HAMAP]

Taxonomic identifier

349307 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosaetaceae › Methanosaeta

Protein attributes

Sequence length	271 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361
Subcellular location	Cytoplasm By similarity HAMAP MF_00361.
Sequence similarities	Belongs to the NAD kinase family. HAMAP MF_00361

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00361
Ligand	ATP-binding HAMAP MF_00361 NAD HAMAP MF_00361 NADP HAMAP MF_00361 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00361 EMBL ABK14629.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0B7F5 [UniParc]. Last modified November 28, 2006. Version 1. Checksum: 114F258C4940BCA4	FASTA	271	29,775
	10 20 30 40 50 60 MVPIRIGFVS RNDEESIQLA GSLIDHFRSR AEIFVEPELA EHLGWKGTPV EEMDVDFIVS 70 80 90 100 110 120 IGGDGTILRT IHKMEDPRPI LGINMGTVGF LVDVEPKDAV RTIEHLLLGF EVDERTRIET 130 140 150 160 170 180 LLRGERLPPA TNEVALITSS PAKMLDFEIK VNGSPLERLR ADGMIFATST GSTAYAMSAG 190 200 210 220 230 240 GPIVDPHLDA IVLVPVAPFK LSARPWVIRG DSMIEVDLKL PGKEALVVVD GQTMATVTHG 250 260 270 DEIIMRKAER PARFVKASRD GFYEKVKAKL V

References

[1]

"Complete sequence of Methanosaeta thermophila PT." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Smith K.S., Ingram-Smith C., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 6194 / PT.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000477 Genomic DNA. Translation: ABK14629.1.
RefSeq	YP_843269.1. NC_008553.1.
3D structure databases
ProteinModelPortal	A0B7F5.
ModBase	Search...
Protein-protein interaction databases
STRING	A0B7F5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4463053.
GenomeReviews	Gene locus Mthe_0840 in contig CP000477_GR.
KEGG	mtp:Mthe_0840.
NMPDR	fig|349307.7.peg.868.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04399.
HOGENOM	HBG713904.
OMA	DPRLDVI.
PhylomeDB	A0B7F5.
ProtClustDB	CLSK568985.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017438. ATP-NAD_kinase_PpnK-typ_a/b. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. polyP/ATP_NADK_prd. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit. G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KO	K00858.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0B7F5_METTP

Accession

Primary (citable) accession number: A0B7F5

Entry history

Integrated into UniProtKB/TrEMBL:	November 28, 2006
Last sequence update:	November 28, 2006
Last modified:	November 16, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)