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A0B7E0 (A0B7E0_METTP) Unreviewed, UniProtKB/TrEMBL

Last modified November 16, 2011. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydrodipicolinate reductase HAMAP MF_00102
Short name=DHPR HAMAP MF_00102
EC=1.3.1.26 HAMAP MF_00102
Gene names
Name:dapB HAMAP MF_00102
Ordered Locus Names:Mthe_0825
OrganismMethanosaeta thermophila (strain DSM 6194 / PT) (Methanothrix thermophila (strain DSM 6194 / PT)) [Complete proteome] [HAMAP]
Taxonomic identifier349307 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosaetaceae › Methanosaeta

Protein attributes

Sequence length257 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ = (S)-2,3-dihydrodipicolinate + NAD(P)H. HAMAP MF_00102

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4. HAMAP MF_00102

Subcellular location

Cytoplasm By similarity HAMAP MF_00102.

Sequence similarities

Belongs to the dihydrodipicolinate reductase family. HAMAP MF_00102

Sequences

Sequence LengthMass (Da)Tools
A0B7E0 [UniParc].

Last modified November 28, 2006. Version 1.
Checksum: CE7972A2C2B015C0

FASTA25727,529
        10         20         30         40         50         60 
MTDVALTGAK GRMGSLIIDE IRSSPDLKLV AAIDIIGIGD RVLGDVCVSD ARDVQRVLRE 

        70         80         90        100        110        120 
SRPDVLIDFT VPSAALENIH AAADTGVALV VGTTGFSEEQ LSIIEEMIKS AGIAAVISPN 

       130        140        150        160        170        180 
FSLGVNVFWK LVEMAARSLS DYDVEVIEAH HRKKKDAPSG TAMRTVEILS RSLGIEDVRH 

       190        200        210        220        230        240 
GREGMCERGR EIGVHAVRAG DIVGDHTVLF AGPGERIEIK HQAHSRSAFA RGALRAARWV 

       250 
VKAPPGIHSM EEVLASS

« Hide

References

[1]"Complete sequence of Methanosaeta thermophila PT."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Smith K.S., Ingram-Smith C., Richardson P.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 6194 / PT.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000477 Genomic DNA. Translation: ABK14614.1.
RefSeqYP_843254.1. NC_008553.1.

3D structure databases

ProteinModelPortalA0B7E0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0B7E0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4462968.
GenomeReviewsGene locus Mthe_0825 in contig CP000477_GR.
KEGGmtp:Mthe_0825.
NMPDRfig|349307.7.peg.854.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG05038.
HOGENOMHBG594002.
OMANTFDVLD.
PhylomeDBA0B7E0.
ProtClustDBPRK00048.

Family and domain databases

HAMAPMF_00102. DapB.
[Tree]
InterProIPR022663. DapB_C.
IPR000846. DapB_N.
IPR022664. DapB_N_CS.
IPR011770. Dihydrodipicolinate_Rdtase.
IPR023940. Dihydrodipicolinate_Rdtase_bac.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00215.
PANTHERPTHR20836. DapB_bac/pln. 1 hit.
PfamPF05173. DapB_C. 1 hit.
PF01113. DapB_N. 1 hit.
[Graphical view]
PIRSFPIRSF000161. DHPR. 1 hit.
TIGRFAMsTIGR00036. DapB. 1 hit.
PROSITEPS01298. DAPB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0B7E0_METTP
AccessionPrimary (citable) accession number: A0B7E0
Entry history
Integrated into UniProtKB/TrEMBL: November 28, 2006
Last sequence update: November 28, 2006
Last modified: November 16, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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