A0B7C4 (A0B7C4_METTP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
F420-dependent methylenetetrahydromethanopterin dehydrogenase HAMAP MF_00058
Short name=MTD HAMAP MF_00058
EC=1.5.99.9 HAMAP MF_00058

Alternative name(s):
Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase HAMAP MF_00058

Gene names

Name:	mtd HAMAP MF_00058
Ordered Locus Names:	Mthe_0809

Organism

Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrix thermophila (strain DSM 6194 / PT)) [Complete proteome] [HAMAP]

Taxonomic identifier

349307 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosaetaceae › Methanosaeta

Protein attributes

Sequence length	275 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the oxidation of methylene-H4MPT to methenyl-H4MPT+ By similarity. HAMAP MF_00058
Catalytic activity	5,10-methylenetetrahydromethanopterin + coenzyme F420 = 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420. HAMAP MF_00058
Sequence similarities	Belongs to the MTD family. HAMAP MF_00058

Ontologies

Keywords
Biological process	One-carbon metabolism HAMAP MF_00058
Molecular function	Oxidoreductase HAMAP MF_00058 EMBL ABK14598.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	methanogenesis Inferred from electronic annotation. Source: InterPro one-carbon metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ferredoxin hydrogenase activity Inferred from electronic annotation. Source: InterPro methylenetetrahydromethanopterin dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0B7C4 [UniParc]. Last modified November 28, 2006. Version 1. Checksum: FC4F98A1F977F41A	FASTA	275	29,488
	10 20 30 40 50 60 MFKIGFIKLG NIASSLVVDL ALDEIAERTE IESKVVSHGP KMSRGEGERL AEEMRAWGPQ 70 80 90 100 110 120 MVVVVSPNAA TPGPTAARSM LKGIPLIVIS DGPTKKEARD AMETEGFGYI ILPMDPLIGA 130 140 150 160 170 180 KREFLDPAEM AIFNADALKV LSICGAVRLV QEEIDRAIAS VAAGSPQLPH ILATPELCAE 190 200 210 220 230 240 RMDFANPYAR AKAIAALYMA QTAASIDAQA CFRLKELEAI ALAAAAGHEV IRAAARLADE 250 260 270 ARELEKSGDT VSRKPHARSG DLLVKRKLLE KPARI

References

[1]

"Complete sequence of Methanosaeta thermophila PT." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Smith K.S., Ingram-Smith C., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 6194 / PT.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000477 Genomic DNA. Translation: ABK14598.1.
RefSeq	YP_843238.1. NC_008553.1.
3D structure databases
ProteinModelPortal	A0B7C4.
ModBase	Search...
Protein-protein interaction databases
STRING	A0B7C4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4462100.
GenomeReviews	Gene locus Mthe_0809 in contig CP000477_GR.
KEGG	mtp:Mthe_0809.
NMPDR	fig|349307.7.peg.838.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG04866.
HOGENOM	HBG538567.
OMA	NPYAKAK.
ProtClustDB	PRK00994.
Family and domain databases
HAMAP	MF_00058. MTD. [Tree]
InterPro	IPR002844. Methylene_DH. [Graphical view]
KO	K00319.
Pfam	PF01993. MTD. 1 hit. [Graphical view]
PIRSF	PIRSF005627. MTD. 1 hit.
ProDom	PD017604. Methylene_DH. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF102324. MeTD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0B7C4_METTP

Accession

Primary (citable) accession number: A0B7C4

Entry history

Integrated into UniProtKB/TrEMBL:	November 28, 2006
Last sequence update:	November 28, 2006
Last modified:	November 16, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)