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Protein

Superoxide dismutase

Gene

Mthe_0685

Organism
Methanosaeta thermophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) (Methanothrix thermophila)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi36Divalent metal cationUniRule annotation1
Metal bindingi84Divalent metal cationUniRule annotation1
Metal bindingi168Divalent metal cationUniRule annotation1
Metal bindingi172Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandMetal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciMTHE349307:G12X8-689-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Mthe_0685Imported
OrganismiMethanosaeta thermophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) (Methanothrix thermophila)Imported
Taxonomic identifieri349307 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosaetaceaeMethanosaeta
Proteomesi
  • UP000000674 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi349307.Mthe_0685.

Structurei

3D structure databases

ProteinModelPortaliA0B701.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 91Sod_Fe_NInterPro annotationAdd BLAST80
Domaini99 – 201Sod_Fe_CInterPro annotationAdd BLAST103

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04147. Archaea.
COG0605. LUCA.
HOGENOMiHOG000013583.
KOiK04564.
OMAiKWGSFDK.
OrthoDBiPOG093Z0AKF.

Family and domain databases

InterProiView protein in InterPro
IPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
PfamiView protein in Pfam
PF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiView protein in PROSITE
PS00088. SOD_MN. 1 hit.

Sequencei

Sequence statusi: Complete.

A0B701-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCILFFMTQK FYTLPELPYG AKDLEPYISE AQLKLHHDKH HLAYVNGANA
60 70 80 90 100
ILEKLDKARR EGADIDQKST LKELSFHIGG HLLHSLFWAN MRKPPSVGPV
110 120 130 140 150
GALADEIKDE FGSFERFRKE FTAAAVSVEG SGWAALAYCM QTRRPIIMQI
160 170 180 190 200
EKHNTNICPM FRLLLVLDVW EHAYYLDYRN DRAKFVEAFW QIADWEEANR

RFESLIGK
Length:208
Mass (Da):24,124
Last modified:November 28, 2006 - v1
Checksum:iF738B9E4AFACC8DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000477 Genomic DNA. Translation: ABK14475.1.

Genome annotation databases

EnsemblBacteriaiABK14475; ABK14475; Mthe_0685.
KEGGimtp:Mthe_0685.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA0B701_METTP
AccessioniPrimary (citable) accession number: A0B701
Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2006
Last sequence update: November 28, 2006
Last modified: June 7, 2017
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported