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A0B6E7

- RPON_METTP

UniProt

A0B6E7 - RPON_METTP

Protein

DNA-directed RNA polymerase subunit N

Gene

rpoN

Organism
Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrix thermophila (strain DSM 6194 / PT))
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

    Catalytic activityi

    Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi6 – 61ZincUniRule annotation
    Metal bindingi9 – 91ZincUniRule annotation
    Metal bindingi42 – 421ZincUniRule annotation
    Metal bindingi43 – 431ZincUniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-HAMAP
    2. DNA-directed RNA polymerase activity Source: UniProtKB-HAMAP
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. transcription, DNA-templated Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    Transcription

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciMMET349307:GHKI-489-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA-directed RNA polymerase subunit NUniRule annotation (EC:2.7.7.6UniRule annotation)
    Gene namesi
    Name:rpoNUniRule annotation
    Ordered Locus Names:Mthe_0480
    OrganismiMethanosaeta thermophila (strain DSM 6194 / PT) (Methanothrix thermophila (strain DSM 6194 / PT))
    Taxonomic identifieri349307 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosaetaceaeMethanosaeta
    ProteomesiUP000000674: Chromosome

    Subcellular locationi

    Keywords - Cellular componenti

    DNA-directed RNA polymerase

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 6161DNA-directed RNA polymerase subunit NPRO_0000304194Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi349307.Mthe_0480.

    Structurei

    3D structure databases

    ProteinModelPortaliA0B6E7.
    SMRiA0B6E7. Positions 1-52.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1644.
    HOGENOMiHOG000109502.
    KOiK03058.
    OMAiQRYCCRR.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    HAMAPiMF_00250. RNApol_arch_N.
    InterProiIPR009057. Homeodomain-like.
    IPR023580. RNA_pol_su_RPB10.
    IPR020789. RNA_pol_suN_Zn-BS.
    IPR000268. RNAP_N/Rpb10.
    [Graphical view]
    PfamiPF01194. RNA_pol_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005653. RNA_pol_N/8_sub. 1 hit.
    ProDomiPD006539. RNA_pol_N/8_sub. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF46924. SSF46924. 1 hit.
    PROSITEiPS01112. RNA_POL_N_8KD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0B6E7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIPVRCFSCG KVISSVWEEY RERIKSEPPG KVMDDLGIER YCCRRMLLSH   50
    VEVVEMLRRY Q 61
    Length:61
    Mass (Da):7,309
    Last modified:November 28, 2006 - v1
    Checksum:i9ECCA60C57A3FEC6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000477 Genomic DNA. Translation: ABK14271.1.
    RefSeqiYP_842911.1. NC_008553.1.

    Genome annotation databases

    EnsemblBacteriaiABK14271; ABK14271; Mthe_0480.
    GeneIDi4463097.
    KEGGimtp:Mthe_0480.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000477 Genomic DNA. Translation: ABK14271.1 .
    RefSeqi YP_842911.1. NC_008553.1.

    3D structure databases

    ProteinModelPortali A0B6E7.
    SMRi A0B6E7. Positions 1-52.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 349307.Mthe_0480.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK14271 ; ABK14271 ; Mthe_0480 .
    GeneIDi 4463097.
    KEGGi mtp:Mthe_0480.

    Phylogenomic databases

    eggNOGi COG1644.
    HOGENOMi HOG000109502.
    KOi K03058.
    OMAi QRYCCRR.

    Enzyme and pathway databases

    BioCyci MMET349307:GHKI-489-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    HAMAPi MF_00250. RNApol_arch_N.
    InterProi IPR009057. Homeodomain-like.
    IPR023580. RNA_pol_su_RPB10.
    IPR020789. RNA_pol_suN_Zn-BS.
    IPR000268. RNAP_N/Rpb10.
    [Graphical view ]
    Pfami PF01194. RNA_pol_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005653. RNA_pol_N/8_sub. 1 hit.
    ProDomi PD006539. RNA_pol_N/8_sub. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF46924. SSF46924. 1 hit.
    PROSITEi PS01112. RNA_POL_N_8KD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 6194 / PT.

    Entry informationi

    Entry nameiRPON_METTP
    AccessioniPrimary (citable) accession number: A0B6E7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: November 28, 2006
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3