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A0B6E7 (RPON_METTP) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit N

EC=2.7.7.6
Gene names
Name:rpoN
Ordered Locus Names:Mthe_0480
OrganismMethanosaeta thermophila (strain DSM 6194 / PT) (Methanothrix thermophila (strain DSM 6194 / PT)) [Complete proteome] [HAMAP]
Taxonomic identifier349307 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosaetaceaeMethanosaeta

Protein attributes

Sequence length61 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. HAMAP-Rule MF_00250

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_00250

Sequence similarities

Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.

Ontologies

Keywords
   Biological processTranscription
   Cellular componentDNA-directed RNA polymerase
   LigandMetal-binding
Zinc
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranscription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

DNA-directed RNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 6161DNA-directed RNA polymerase subunit N HAMAP-Rule MF_00250
PRO_0000304194

Sites

Metal binding61Zinc By similarity
Metal binding91Zinc By similarity
Metal binding421Zinc By similarity
Metal binding431Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
A0B6E7 [UniParc].

Last modified November 28, 2006. Version 1.
Checksum: 9ECCA60C57A3FEC6

FASTA617,309
        10         20         30         40         50         60 
MIPVRCFSCG KVISSVWEEY RERIKSEPPG KVMDDLGIER YCCRRMLLSH VEVVEMLRRY 


Q 

« Hide

References

[1]"Complete sequence of Methanosaeta thermophila PT."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., Smith K.S., Ingram-Smith C., Richardson P.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 6194 / PT.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000477 Genomic DNA. Translation: ABK14271.1.
RefSeqYP_842911.1. NC_008553.1.

3D structure databases

ProteinModelPortalA0B6E7.
SMRA0B6E7. Positions 1-52.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING349307.Mthe_0480.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK14271; ABK14271; Mthe_0480.
GeneID4463097.
KEGGmtp:Mthe_0480.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1644.
HOGENOMHOG000109502.
KOK03058.
OMAQLKRYCC.
ProtClustDBPRK04016.

Enzyme and pathway databases

BioCycMMET349307:GHKI-489-MONOMER.

Family and domain databases

Gene3D1.10.10.60. 1 hit.
HAMAPMF_00250. RNApol_arch_N.
InterProIPR009057. Homeodomain-like.
IPR023580. RNA_pol_su_RPB10.
IPR020789. RNA_pol_suN_Zn-BS.
IPR000268. RNAP_N/Rpb10.
[Graphical view]
PfamPF01194. RNA_pol_N. 1 hit.
[Graphical view]
PIRSFPIRSF005653. RNA_pol_N/8_sub. 1 hit.
ProDomPD006539. RNA_pol_N/8_sub. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF46924. SSF46924. 1 hit.
PROSITEPS01112. RNA_POL_N_8KD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRPON_METTP
AccessionPrimary (citable) accession number: A0B6E7
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: November 28, 2006
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families