A0B6E7 (RPON_METTP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit N
EC=2.7.7.6

Gene names

Name:	rpoN
Ordered Locus Names:	Mthe_0480

Organism

Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrix thermophila (strain DSM 6194 / PT)) [Complete proteome] [HAMAP]

Taxonomic identifier

349307 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosaetaceae › Methanosaeta › Methanosaeta thermophila

Protein attributes

Sequence length	61 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. HAMAP-Rule MF_00250
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_00250
Sequence similarities	Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Ligand	Metal-binding Zinc
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: HAMAP
Molecular_function	DNA binding Inferred from electronic annotation. Source: HAMAP DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 61	61	DNA-directed RNA polymerase subunit N HAMAP-Rule MF_00250		PRO_0000304194
Sites
	Metal binding	6	1	Zinc By similarity
	Metal binding	9	1	Zinc By similarity
	Metal binding	42	1	Zinc By similarity
	Metal binding	43	1	Zinc By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0B6E7 [UniParc]. Last modified November 28, 2006. Version 1. Checksum: 9ECCA60C57A3FEC6	FASTA	61	7,309
	10 20 30 40 50 60 MIPVRCFSCG KVISSVWEEY RERIKSEPPG KVMDDLGIER YCCRRMLLSH VEVVEMLRRY Q

References

[1]

"Complete sequence of Methanosaeta thermophila PT." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Smith K.S., Ingram-Smith C., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 6194 / PT.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000477 Genomic DNA. Translation: ABK14271.1.
RefSeq	YP_842911.1. NC_008553.1.
3D structure databases
ProteinModelPortal	A0B6E7.
SMR	A0B6E7. Positions 1-52.
ModBase	Search...
Protein-protein interaction databases
STRING	349307.Mthe_0480.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABK14271; ABK14271; Mthe_0480.
GeneID	4463097.
KEGG	mtp:Mthe_0480.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1644.
HOGENOM	HOG000109502.
KO	K03058.
OMA	CRRMILT.
ProtClustDB	PRK04016.
Enzyme and pathway databases
BioCyc	MMET349307:GHKI-530-MONOMER.
Family and domain databases
Gene3D	1.10.10.60. 1 hit.
HAMAP	MF_00250. RNApol_arch_N.
InterPro	IPR009057. Homeodomain-like. IPR023580. RNA_pol_su_RPB10. IPR020789. RNA_pol_suN_Zn-BS. IPR000268. RNAP_N/Rpb10. [Graphical view]
PANTHER	PTHR23413:SF2. PTHR23413:SF2. 1 hit.
Pfam	PF01194. RNA_pol_N. 1 hit. [Graphical view]
PIRSF	PIRSF005653. RNA_pol_N/8_sub. 1 hit.
ProDom	PD006539. RNA_pol_N/8_sub. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF46924. RNA_pol_N/8_sub. 1 hit.
PROSITE	PS01112. RNA_POL_N_8KD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RPON_METTP

Accession

Primary (citable) accession number: A0B6E7

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	November 28, 2006
Last modified:	May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program