A0B571 (ACYP_METTP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	Mthe_0042

Organism

Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrix thermophila (strain DSM 6194 / PT)) [Complete proteome] [HAMAP]

Taxonomic identifier

349307 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosaetaceae › Methanosaeta

Protein attributes

Sequence length	90 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 90	90	Acylphosphatase HAMAP MF_01450		PRO_0000326861
Regions
	Domain	4 – 90	87	Acylphosphatase-like
Sites
	Active site	19	1	By similarity
	Active site	37	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0B571 [UniParc]. Last modified November 28, 2006. Version 1. Checksum: D614128C9B247A85	FASTA	90	9,672
	10 20 30 40 50 60 MTICVRVRVS GRVQGVGYRY YTTTHAKALG VKGWIRNLPG GGVEAVLEGE RKSVGELLGL 70 80 90 MKSGPSGAMV SGMEIAEVEC KGHDDFKIIY

References

[1]

"Complete sequence of Methanosaeta thermophila PT." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Kim E., Smith K.S., Ingram-Smith C., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 6194 / PT.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000477 Genomic DNA. Translation: ABK13845.1.
RefSeq	YP_842485.1. NC_008553.1.
3D structure databases
ProteinModelPortal	A0B571.
ModBase	Search...
Protein-protein interaction databases
STRING	A0B571.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4462734.
GenomeReviews	Gene locus Mthe_0042 in contig CP000477_GR.
KEGG	mtp:Mthe_0042.
NMPDR	fig|349307.7.peg.43.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG12401.
HOGENOM	HBG750266.
OMA	YFRDFTR.
PhylomeDB	A0B571.
Enzyme and pathway databases
BioCyc	MTHE349307:MTHE_0042-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR020456. Acylphosphatase. IPR001792. Acylphosphatase-like. [Graphical view]
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
PRINTS	PR00112. ACYLPHPHTASE.
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. False negative. PS00151. ACYLPHOSPHATASE_2. False negative. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_METTP

Accession

Primary (citable) accession number: A0B571

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	November 28, 2006
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program