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A0B2H8 (A0B2H8_BURCH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyrroloquinoline-quinone synthase HAMAP MF_00654
EC=1.3.3.11 HAMAP MF_00654
Alternative name(s):
Coenzyme PQQ synthesis protein C HAMAP MF_00654
Pyrroloquinoline quinone biosynthesis protein C HAMAP MF_00654
Gene names
Name:pqqC HAMAP MF_00654
Ordered Locus Names:Bcen2424_5121
OrganismBurkholderia cenocepacia (strain HI2424) [Complete proteome] [HAMAP] EMBL ABK11854.1
Taxonomic identifier331272 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length239 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654

Catalytic activity

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654

Pathway

Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654

Sequence similarities

Belongs to the pqqC family. HAMAP MF_00654

Ontologies

Keywords
   Biological processPQQ biosynthesis HAMAP MF_00654
   Molecular functionOxidoreductase HAMAP MF_00654
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpyrroloquinoline quinone biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionpyrroloquinoline-quinone synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A0B2H8 [UniParc].

Last modified November 28, 2006. Version 1.
Checksum: 0E28C78DE1FE17CF

FASTA23927,269
        10         20         30         40         50         60 
MNAPIPATAL HATPWTATEF EARLRALESR YHIHHPFNRR LNSGACSPTQ IRGWVANRFY 

        70         80         90        100        110        120 
YQICIPLKDA AILSNCPDRE TRRRWIQRLI DHDGQGDNAG GIEAWVRLGE ACGLTRDELW 

       130        140        150        160        170        180 
SLEHVLPGVR FAVDAYVNFA RRAPWQEAVC SSLTEMFAPQ IHLDRLAGWP SHYPWIEPAG 

       190        200        210        220        230 
LHYFRSRVPL AQRDVEHGLA VTLAHFTTPD AQQRALGILQ FKLDILWSML DAVEKAYPL

« Hide

References

[1]"Complete sequence of chromosome 2 of Burkholderia cenocepacia HI2424."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000459 Genomic DNA. Translation: ABK11854.1.
RefSeqYP_838747.1. NC_008543.1.

3D structure databases

ProteinModelPortalA0B2H8.
SMRA0B2H8. Positions 20-239.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0B2H8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4453800.
GenomeReviewsGene locus Bcen2424_5121 in contig CP000459_GR.
KEGGbch:Bcen2424_5121.
PATRIC19067878. VBIBurCen15205_5261.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG5424.
HOGENOMHBG288944.
OMADSWPQHY.
ProtClustDBPRK05157.

Family and domain databases

HAMAPMF_00654. PQQ_syn_PqqC.
[Tree]
InterProIPR016084. Haem_Oase-like_multi-hlx.
IPR011845. PQQ_synth_PqqC.
IPR004305. TENA/THI4/PQQ_synthPqqC_dom.
[Graphical view]
Gene3DG3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
KOK06137.
PfamPF03070. TENA_THI-4. 1 hit.
[Graphical view]
SUPFAMSSF48613. Heme_oxygenase. 1 hit.
TIGRFAMsTIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA0B2H8_BURCH
AccessionPrimary (citable) accession number: A0B2H8
Entry history
Integrated into UniProtKB/TrEMBL: November 28, 2006
Last sequence update: November 28, 2006
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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