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A0B2F5 (BETI_BURCH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
HTH-type transcriptional regulator BetI
Gene names
Name:betI
Ordered Locus Names:Bcen2424_5098
OrganismBurkholderia cenocepacia (strain HI2424) [Complete proteome] [HAMAP]
Taxonomic identifier331272 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex

Protein attributes

Sequence length194 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine By similarity. HAMAP-Rule MF_00768

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway [regulation]. HAMAP-Rule MF_00768

Sequence similarities

Contains 1 HTH tetR-type DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 194194HTH-type transcriptional regulator BetI HAMAP-Rule MF_00768
PRO_1000083553

Regions

Domain8 – 6861HTH tetR-type
DNA binding31 – 5020H-T-H motif By similarity

Sequences

Sequence LengthMass (Da)Tools
A0B2F5 [UniParc].

Last modified November 28, 2006. Version 1.
Checksum: BAF2C87D2E0D1B12

FASTA19421,330
        10         20         30         40         50         60 
MPKVGMREIR RAQLIDATLR SIDEAGLPGT TLASVAQRAN ISTGIVSHYF GDKDGLLEAT 

        70         80         90        100        110        120 
MRHVLRDLWS ATTRRRVAAR KDPRSRLRAV VAANFDDTQV SAPVMKTWLA FWSQSMHDPM 

       130        140        150        160        170        180 
LKRLQHVNTR RLHSNLCAEF AKALPLAKAR EAASGLAALI DGLWLRGALA GGPIDTRAAL 

       190 
KLAHDYIDLL LASD 

« Hide

References

[1]"Complete sequence of chromosome 2 of Burkholderia cenocepacia HI2424."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HI2424.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000459 Genomic DNA. Translation: ABK11831.1.
RefSeqYP_838724.1. NC_008543.1.

3D structure databases

ProteinModelPortalA0B2F5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING331272.Bcen2424_5098.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK11831; ABK11831; Bcen2424_5098.
GeneID4453674.
KEGGbch:Bcen2424_5098.
PATRIC19067828. VBIBurCen15205_5236.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1309.
HOGENOMHOG000248227.
KOK02167.
OMAGHYPPET.
OrthoDBEOG6FFS5N.

Enzyme and pathway databases

BioCycBCEN331272:GHR7-5173-MONOMER.
UniPathwayUPA00529.

Family and domain databases

Gene3D1.10.357.10. 1 hit.
HAMAPMF_00768. HTH_type_BetI.
InterProIPR023772. DNA-bd_HTH_TetR-type_CS.
IPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
IPR017757. Tscrpt_rep_BetI.
[Graphical view]
PfamPF00440. TetR_N. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
TIGRFAMsTIGR03384. betaine_BetI. 1 hit.
PROSITEPS01081. HTH_TETR_1. 1 hit.
PS50977. HTH_TETR_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETI_BURCH
AccessionPrimary (citable) accession number: A0B2F5
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 28, 2006
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways