Skip Header

Contribute Send feedback
Read comments (?) or add your own

A0B1B0 (A0B1B0_BURCH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Probable L-aspartate dehydrogenase HAMAP MF_01265
EC=1.4.1.21 HAMAP MF_01265
Gene names
Name:nadX HAMAP MF_01265
Ordered Locus Names:Bcen2424_4702
OrganismBurkholderia cenocepacia (strain HI2424) [Complete proteome] [HAMAP] EMBL ABK11436.1
Taxonomic identifier331272 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity. HAMAP MF_01265

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity. HAMAP MF_01265

Sequence similarities

Belongs to the L-aspartate dehydrogenase family. HAMAP MF_01265

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2281 By similarity HAMAP MF_01265
Binding site1321NAD; via amide nitrogen By similarity HAMAP MF_01265
Binding site1981NAD By similarity HAMAP MF_01265

Sequences

Sequence LengthMass (Da)Tools
A0B1B0 [UniParc].

Last modified November 28, 2006. Version 1.
Checksum: AB0136BC54F88DB9

FASTA27528,589
        10         20         30         40         50         60 
MHNGQKRARA PVDVAMIGFG AIGAAVYRAV EHDASLRVAH VIVPEHQRAA VQRELGGAVE 

        70         80         90        100        110        120 
VVSSVDALAR RPEFALECAG HGALVDHVVP LLKAGTDCAV ASIGALSDLA LLDVLSRAAD 

       130        140        150        160        170        180 
EGGTTVTLLS GAIGGIDALA SAKEGGLDEV RYVGRKPPLG WLGTPAEELC DLRAMTEEKV 

       190        200        210        220        230        240 
IFEGSARDAA RLYPKNANVA ATVALAGLGL DATHVRLIAD PAVERNVHRI TARGAFGEMS 

       250        260        270 
LEMSGKPLPD NPKTSALTAY SAIRALRNRA ACCVI

« Hide

References

[1]"Complete sequence of chromosome 2 of Burkholderia cenocepacia HI2424."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000459 Genomic DNA. Translation: ABK11436.1.
RefSeqYP_838329.1. NC_008543.1.

3D structure databases

ProteinModelPortalA0B1B0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0B1B0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4453179.
GenomeReviewsGene locus Bcen2424_4702 in contig CP000459_GR.
KEGGbch:Bcen2424_4702.
PATRIC19067021. VBIBurCen15205_4834.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1712.
HOGENOMHBG649642.
OMAECAGHSA.
ProtClustDBPRK13303.

Family and domain databases

HAMAPMF_01265. NadX.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
IPR020626. Asp_DH_NAD_syn_prok.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK06989.
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA0B1B0_BURCH
AccessionPrimary (citable) accession number: A0B1B0
Entry history
Integrated into UniProtKB/TrEMBL: November 28, 2006
Last sequence update: November 28, 2006
Last modified: December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info