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Protein

Catalase

Gene

Bcen2424_3898

Organism
Burkholderia cenocepacia (strain HI2424)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

2 H2O2 = O2 + 2 H2O.UniRule annotation

Cofactori

hemeUniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi357 – 3571Iron (heme axial ligand)UniRule annotation

GO - Molecular functioni

  1. catalase activity Source: UniProtKB-EC
  2. heme binding Source: InterPro
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. hydrogen peroxide catabolic process Source: UniProtKB-KW
  2. response to oxidative stress Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxideUniRule annotation

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

BioCyciBCEN331272:GHR7-3972-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
CatalaseUniRule annotation (EC:1.11.1.6UniRule annotation)
Gene namesi
Ordered Locus Names:Bcen2424_3898Imported
OrganismiBurkholderia cenocepacia (strain HI2424)Imported
Taxonomic identifieri331272 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
ProteomesiUP000000776 Componenti: Chromosome 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727 PotentialImportedAdd
BLAST
Chaini28 – 511484 PotentialImportedPRO_5000148189Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi331272.Bcen2424_3898.

Structurei

3D structure databases

ProteinModelPortaliA0AZ09.
SMRiA0AZ09. Positions 28-510.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the catalase family.UniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

eggNOGiCOG0753.
HOGENOMiHOG000087852.
KOiK03781.
OMAiMGRIFAY.
OrthoDBiEOG6P5Z9F.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A0AZ09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSSHRVLR HAVAAICVAL SASPYAAELT RDTGAPVGDN QNSQTAGPAG
60 70 80 90 100
PVLLQDSALI EKLQRFDRER IPERVVHARG TGAFGEFVPS ADISDLTKAK
110 120 130 140 150
VFTPGTRTPV FVRFSTVMGY RGSPEQARDP RGFAVKFYTQ QGNWDMVGIN
160 170 180 190 200
WPVFFIRDGI KFPDFVHANK PSAVTGVQDP NLAFDFFAHT PEATHMLTRL
210 220 230 240 250
YTDEGMPDSY RRMDGFAVHA FKFVNAQGDV HYVKFHWKSQ QGVHGLRPQE
260 270 280 290 300
IPASIGRDWN LMTNDLYGAL KQGDFPKWDL YVQVLTPKDL NRFDFDALDD
310 320 330 340 350
TKVWTGVPER KIGTMTLNRV PDNYFQSTEE SAFAPSRLVP GIEPSEDRML
360 370 380 390 400
QDRLFAYADT QMYRLGANYM DLPINRPVVP VVNNNQDGKM NAGDRKGEVN
410 420 430 440 450
YEPSTLNELA QDPQYKSVRM TLSGTTQQEA IRKKLPFRQA GEYYRSLSQQ
460 470 480 490 500
DKDDLVTALS GDLGQVKNAQ NQYAMLSYFY KADADYGTRL AQAVHANVQQ
510
VQSLAAKLSD N
Length:511
Mass (Da):57,247
Last modified:November 28, 2006 - v1
Checksum:i6B83F36F338C1508
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000459 Genomic DNA. Translation: ABK10635.1.
RefSeqiYP_837528.1. NC_008543.1.

Genome annotation databases

EnsemblBacteriaiABK10635; ABK10635; Bcen2424_3898.
KEGGibch:Bcen2424_3898.
PATRICi19065316. VBIBurCen15205_3985.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000459 Genomic DNA. Translation: ABK10635.1.
RefSeqiYP_837528.1. NC_008543.1.

3D structure databases

ProteinModelPortaliA0AZ09.
SMRiA0AZ09. Positions 28-510.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi331272.Bcen2424_3898.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK10635; ABK10635; Bcen2424_3898.
KEGGibch:Bcen2424_3898.
PATRICi19065316. VBIBurCen15205_3985.

Phylogenomic databases

eggNOGiCOG0753.
HOGENOMiHOG000087852.
KOiK03781.
OMAiMGRIFAY.
OrthoDBiEOG6P5Z9F.

Enzyme and pathway databases

BioCyciBCEN331272:GHR7-3972-MONOMER.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 2 of Burkholderia cenocepacia HI2424."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.
    , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HI2424Imported.

Entry informationi

Entry nameiA0AZ09_BURCH
AccessioniPrimary (citable) accession number: A0AZ09
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2006
Last sequence update: November 28, 2006
Last modified: April 1, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.