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A0AWY9 (MQO_BURCH) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:Bcen2424_3168
OrganismBurkholderia cenocepacia (strain HI2424) [Complete proteome] [HAMAP]
Taxonomic identifier331272 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length553 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Sequence caution

The sequence ABK09915.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 553553Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_0000325490

Sequences

Sequence LengthMass (Da)Tools
A0AWY9 [UniParc].

Last modified March 18, 2008. Version 2.
Checksum: 113DCA21FC45E048

FASTA55360,584
        10         20         30         40         50         60 
MKKGSAVIKT LRVILSALAL CVATSSAHAA DTKKVDVLLV GGGIMSSTLG VWLHELQPNW 

        70         80         90        100        110        120 
SMTMVERLDG VALESSNGWN NAGTGHSALA ELNYTPEKAD GKVDISKAIE INESFQISRQ 

       130        140        150        160        170        180 
FWAWQVKQGV LKNPHSFINS TPHMSFVWGD DNVRFLKKRY EALQASPLFR GMQYSEDYDQ 

       190        200        210        220        230        240 
IKQWVPLMME GRDRNQKVAA TWTPIGTDVN FGEITRQFVG YLKTQPNFTL SLSSEVREIT 

       250        260        270        280        290        300 
RNADGTWHVS WVKLHSDEPP QSVDAKFVFI GAGGGALHLL QASGIPEAKD YGAFPVGGSF 

       310        320        330        340        350        360 
LVTDNPEVVK QHLAKAYGKA SVGSPPMSVP HLDTRIIDGK KIILFGPFAT FSTKFLKNGS 

       370        380        390        400        410        420 
YFDLAKSTNL HNVAPMMRVG VDEFPLVQYL AGQLMLTDDD RFNALKEYFP NAKKEDWRLW 

       430        440        450        460        470        480 
QAGQRVQIIK RDPVKGGVLK LGTEIVASQD GSIAGLLGAS PGASTAAPIM LNLMQKVFKD 

       490        500        510        520        530        540 
KVATPEWQQK IRQIVPSYGT KLNDSPAKVV EEWTYTSDVL QLSPPPKIDL GAPSQATGNA 

       550 
PARPAKASAD MAL

« Hide

References

[1]"Complete sequence of chromosome 2 of Burkholderia cenocepacia HI2424."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Kim E., LiPuma J.J., Gonzalez C.F., Konstantinidis K., Tiedje J.M., Richardson P.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HI2424.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000459 Genomic DNA. Translation: ABK09915.1. Different initiation.
RefSeqYP_836808.2. NC_008543.1.

3D structure databases

ProteinModelPortalA0AWY9.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0AWY9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4453418.
GenomeReviewsGene locus Bcen2424_3168 in contig CP000459_GR.
KEGGbch:Bcen2424_3168.
PATRIC19063850. VBIBurCen15205_3256.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0579.
HOGENOMHBG289663.
ProtClustDBPRK05257.

Enzyme and pathway databases

BioCycBCEN331272:BCEN2424_3168-MONOMER.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_BURCH
AccessionPrimary (citable) accession number: A0AWY9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: December 14, 2011
This is version 34 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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