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Protein

Pyrophosphatase PpaX

Gene

ppaX

Organism
Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool.UniRule annotation

Catalytic activityi

Diphosphate + H2O = 2 phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei11NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandMagnesium

Enzyme and pathway databases

BioCyciLWEL386043:G1GJF-2515-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Pyrophosphatase PpaXUniRule annotation (EC:3.6.1.1UniRule annotation)
Gene namesi
Name:ppaXUniRule annotation
Ordered Locus Names:lwe2429
OrganismiListeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)
Taxonomic identifieri386043 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
Proteomesi
  • UP000000779 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000671901 – 217Pyrophosphatase PpaXAdd BLAST217

Interactioni

Protein-protein interaction databases

STRINGi386043.lwe2429

Structurei

3D structure databases

ProteinModelPortaliA0ALG5
SMRiA0ALG5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PpaX family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107XGZ Bacteria
COG0546 LUCA
HOGENOMiHOG000248344
KOiK06019
OMAiLLIFDWD
OrthoDBiPOG091H010N

Family and domain databases

Gene3Di1.10.150.240, 1 hit
3.40.50.1000, 2 hits
HAMAPiMF_01250 Pyrophosphat_PpaX, 1 hit
InterProiView protein in InterPro
IPR036412 HAD-like_sf
IPR006439 HAD-SF_hydro_IA
IPR023214 HAD_sf
IPR023198 PGP-like_dom2
IPR023733 Pyrophosphatase_Ppax
PRINTSiPR00413 HADHALOGNASE
SUPFAMiSSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR01549 HAD-SF-IA-v1, 1 hit

Sequencei

Sequence statusi: Complete.

A0ALG5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGKITTLLF DLDGTLINTN ELIIKTFQAT LQEFLPDRVF TREDILPFIG
60 70 80 90 100
PSLMETFREI NPAHAEEMRV FYREYNLKHH DDLILEYEGV YEAIRVLYEE
110 120 130 140 150
DYKLGIVSTK MYDTIMRGLK VTGLDKFFQV VIGLDQVSNA KPDPEGIEMA
160 170 180 190 200
LSLLNATKEE AIMIGDNYHD IEAGKNAETL TAGVAWAIKG PEHLAQFQPD
210
FMLEKMSDLL AIVRDEE
Length:217
Mass (Da):24,768
Last modified:November 28, 2006 - v1
Checksum:iA1CF491B86420A2E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM263198 Genomic DNA Translation: CAK21847.1
RefSeqiWP_011703165.1, NC_008555.1

Genome annotation databases

EnsemblBacteriaiCAK21847; CAK21847; lwe2429
KEGGilwe:lwe2429

Similar proteinsi

Entry informationi

Entry nameiPPAX_LISW6
AccessioniPrimary (citable) accession number: A0ALG5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 28, 2006
Last modified: March 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health