A0AL74 (FENR2_LISW6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin--NADP reductase 2
Short name=FNR 2
Short name=Fd-NADP+ reductase 2
EC=1.18.1.2

Gene names

Ordered Locus Names:

lwe2338

Organism

Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334) [Complete proteome] [HAMAP]

Taxonomic identifier

386043 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity. HAMAP MF_01685
Subunit structure	Homodimer By similarity. HAMAP MF_01685
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	Ferredoxin--NADP reductase 2 HAMAP MF_01685		PRO_0000364876
Sites
	Binding site	37	1	FAD By similarity
	Binding site	45	1	FAD By similarity
	Binding site	50	1	FAD By similarity
	Binding site	90	1	FAD; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	124	1	FAD; via amide nitrogen By similarity
	Binding site	286	1	FAD By similarity
	Binding site	327	1	FAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0AL74 [UniParc]. Last modified November 28, 2006. Version 1. Checksum: D127B96F624AD355	FASTA	331	36,469
	10 20 30 40 50 60 MDEKTKIYDI TIIGGGPVGL FAAFYAGMRN ASVKIIESLP QLGGQLSTLY PEKYIYDIPG 70 80 90 100 110 120 YPAVRAQELV NNLIQQMKPF DPTIALEEAV ISVEKQVDGT FEIITKKDTH YSKAIVITAG 130 140 150 160 170 180 NGAFEPRRLD LPEAEQYEGK NIHYFINDLS RFSGRRVAVC GGGDSAVDWA LMLEKVASSV 190 200 210 220 230 240 SIVHRRNAFR AHEHSVNNLE KSSITIKTPF IPTEVLGNGD KLTHITLQEV KGDTSETLEI 250 260 270 280 290 300 DDFIINYGFV SSLGPIKNWG LELERNSIIV NSKMETSIPG IYCAGDICTY DGKVKLIATG 310 320 330 FGEAPTAVNN AMNFIDPKTR VQPMHSTSLF E

References

[1]

"Whole-genome sequence of Listeria welshimeri reveals common steps in genome reduction with Listeria innocua as compared to Listeria monocytogenes." Hain T., Steinweg C., Kuenne C.T., Billion A., Ghai R., Chatterjee S.S., Domann E., Kaerst U., Goesmann A., Bekel T., Bartels D., Kaiser O., Meyer F., Puehler A., Weisshaar B., Wehland J., Liang C., Dandekar T. , Lampidis R., Kreft J., Goebel W., Chakraborty T. J. Bacteriol. 188:7405-7415(2006) [PubMed: 16936040] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35897 / DSM 20650 / SLCC5334.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM263198 Genomic DNA. Translation: CAK21756.1.
RefSeq	YP_850535.1. NC_008555.1.
3D structure databases
ProteinModelPortal	A0AL74.
ModBase	Search...
Protein-protein interaction databases
STRING	A0AL74.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4464654.
GenomeReviews	Gene locus lwe2338 in contig AM263198_GR.
KEGG	lwe:lwe2338.
NMPDR	fig|386043.6.peg.2274.
PATRIC	20331935. VBILisWel39304_2349.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0492.
HOGENOM	HBG669726.
OMA	FQVFELG.
ProtClustDB	CLSK2461576.
Enzyme and pathway databases
BioCyc	LWEL386043:LWE2338-MONOMER.
Family and domain databases
HAMAP	MF_01685. FENR2. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR022890. Fd--NADP_Rdtase_type_2. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
KO	K00384.
PANTHER	PTHR22912:SF53. PTHR22912:SF53. 1 hit.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProtoNet	Search...

Entry information

Entry name

FENR2_LISW6

Accession

Primary (citable) accession number: A0AL74

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	November 28, 2006
Last modified:	December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program