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Protein

Asparagine--tRNA ligase

Gene

asnS

Organism
Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-tRNA(Asn).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Asparagine--tRNA ligaseUniRule annotation (EC:6.1.1.22UniRule annotation)
Alternative name(s):
Asparaginyl-tRNA synthetaseUniRule annotation
Short name:
AsnRSUniRule annotation
Gene namesi
Name:asnSUniRule annotation
Ordered Locus Names:lwe1915
OrganismiListeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)
Taxonomic identifieri386043 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
Proteomesi
  • UP000000779 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000514071 – 430Asparagine--tRNA ligaseAdd BLAST430

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi386043.lwe1915.

Structurei

3D structure databases

ProteinModelPortaliA0AK01.
SMRiA0AK01.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C5S. Bacteria.
COG0017. LUCA.
HOGENOMiHOG000226034.
KOiK01893.
OMAiWWYLDTR.
OrthoDBiPOG091H054V.

Family and domain databases

HAMAPiMF_00534. Asn_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR004364. aa-tRNA-synt_II.
IPR006195. aa-tRNA-synth_II.
IPR004522. Asn-tRNA-ligase.
IPR002312. Asp/Asn-tRNA-synth_IIb.
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA.
PANTHERiPTHR22594. PTHR22594. 1 hit.
PfamiView protein in Pfam
PF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti-codon. 1 hit.
PRINTSiPR01042. TRNASYNTHASP.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00457. asnS. 1 hit.
PROSITEiView protein in PROSITE
PS50862. AA_TRNA_LIGASE_II. 1 hit.

Sequencei

Sequence statusi: Complete.

A0AK01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKITINQASE FVGKEVTIGA WLANKRSSGK IAFLQLRDGT GFMQGVVVKA
60 70 80 90 100
EVGDDMFASA KALTQETSLY VTGTINEDTR SPFGYEMAVS GVEVISESHD
110 120 130 140 150
YPITPKEHGT EFLMDHRHLW LRSNRQHAIM KIRNEIIRAS YEFFNKEGFL
160 170 180 190 200
KIDPPILTGS APEGTTELFH TKYFEEDAFL SQSGQLYMEA AAMAFGKVFS
210 220 230 240 250
FGPTFRAEKS KTRRHLIEFW MIEPEMAFYK LEDSLQVQEN YVAYLVKAVL
260 270 280 290 300
DNCRLELDRL GRDVSHLEKM VAPFPRITYT EAIERLHELG FDDIVWGDDF
310 320 330 340 350
GAPHETAIAD SFEKPVFITH YPKAIKPFYM PEDPENNQVV LCADMIAPEG
360 370 380 390 400
YGEIIGGSER IHDLETLQAR MEDFDLDQEA YSWYLDLARY GSVPHSGFGL
410 420 430
GLERTVAWIS GTEHVRETIP FPRLLNRLYP
Length:430
Mass (Da):48,988
Last modified:November 28, 2006 - v1
Checksum:iC3559E22FD228AE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM263198 Genomic DNA. Translation: CAK21333.1.
RefSeqiWP_011702681.1. NC_008555.1.

Genome annotation databases

EnsemblBacteriaiCAK21333; CAK21333; lwe1915.
KEGGilwe:lwe1915.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiSYN_LISW6
AccessioniPrimary (citable) accession number: A0AK01
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 28, 2006
Last modified: June 7, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families