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A0AJS6 (STP1_LISW6) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine phosphatase stp

EC=3.1.3.16
Gene names
Name:stp
Ordered Locus Names:lwe1840
OrganismListeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334) [Complete proteome] [HAMAP]
Taxonomic identifier386043 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria

Protein attributes

Sequence length252 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Protein phosphatase that dephosphorylates EF-Tu By similarity.

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 manganese ions per subunit By similarity.

Subcellular location

Cytoplasm. Membrane; Peripheral membrane protein By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Ontologies

Keywords
   Cellular componentCytoplasm
Membrane
   LigandManganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 252252Serine/threonine phosphatase stp
PRO_0000363065

Regions

Domain2 – 235234PP2C-like

Sites

Metal binding361Manganese 1 By similarity
Metal binding361Manganese 2 By similarity
Metal binding371Manganese 1; via carbonyl oxygen By similarity
Metal binding1941Manganese 2 By similarity
Metal binding2331Manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
A0AJS6 [UniParc].

Last modified November 28, 2006. Version 1.
Checksum: 241D15FBF9C62B0F

FASTA25228,047
        10         20         30         40         50         60 
MHAEFRTDRG RIRHHNEDNG GVFENKDNQP IVIVADGMGG HRAGDVASEM AVRLLSDAWK 

        70         80         90        100        110        120 
ETTALLTAEE IETWLRKEIQ EVNKQIVLYA ESEMDLNGMG TTLVAAIMAK SQVVIANVGD 

       130        140        150        160        170        180 
SRGYLLQNNT LRQLTEDHSL VHELLRTGEI SKEDAMNHPR KNILLRALGV EGKVEVDTFV 

       190        200        210        220        230        240 
VPFQTTDTLL LCSDGLTNMV PETEMEDILK SKRSLSEKAD VFITKANSYG GEDNITVLLV 

       250 
ERNLMQKGRD AS 

« Hide

References

[1]"Whole-genome sequence of Listeria welshimeri reveals common steps in genome reduction with Listeria innocua as compared to Listeria monocytogenes."
Hain T., Steinweg C., Kuenne C.T., Billion A., Ghai R., Chatterjee S.S., Domann E., Kaerst U., Goesmann A., Bekel T., Bartels D., Kaiser O., Meyer F., Puehler A., Weisshaar B., Wehland J., Liang C., Dandekar T. expand/collapse author list , Lampidis R., Kreft J., Goebel W., Chakraborty T.
J. Bacteriol. 188:7405-7415(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35897 / DSM 20650 / SLCC5334.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM263198 Genomic DNA. Translation: CAK21258.1.
RefSeqYP_850037.1. NC_008555.1.

3D structure databases

ProteinModelPortalA0AJS6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING386043.lwe1840.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAK21258; CAK21258; lwe1840.
GeneID4465993.
KEGGlwe:lwe1840.
PATRIC20330885. VBILisWel39304_1849.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000235782.
KOK01090.
OMAHEECQGM.
OrthoDBEOG65N17S.

Enzyme and pathway databases

BioCycLWEL386043:GI5X-1890-MONOMER.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSTP1_LISW6
AccessionPrimary (citable) accession number: A0AJS6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: November 28, 2006
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families