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A0AJ39 (A0AJ39_LISW6) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Arginine biosynthesis bifunctional protein ArgJ HAMAP MF_01106
Gene names
Name:argJ HAMAP MF_01106 EMBL CAK21021.1
Ordered Locus Names:lwe1603
OrganismListeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334) [Complete proteome] [HAMAP] EMBL CAK21021.1
Taxonomic identifier386043 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate By similarity. HAMAP MF_01106

Catalytic activity

Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate. HAMAP MF_01106

N(2)-acetyl-L-ornithine + L-glutamate = L-ornithine + N-acetyl-L-glutamate. HAMAP MF_01106

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1. HAMAP MF_01106

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. HAMAP MF_01106

Subunit structure

Heterotetramer of two alpha and two beta chains By similarity. HAMAP MF_01106

Subcellular location

Cytoplasm By similarity HAMAP MF_01106.

Miscellaneous

Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway By similarity. HAMAP MF_01106

Sequence similarities

Belongs to the ArgJ family. HAMAP MF_01106

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Site184 – 1852Cleavage; by autolysis By similarity HAMAP MF_01106

Sequences

Sequence LengthMass (Da)Tools
A0AJ39 [UniParc].

Last modified November 28, 2006. Version 1.
Checksum: 3D37904EDE8A90E6

FASTA39842,938
        10         20         30         40         50         60 
MELIKGDIAS PKGFYADGKH AGLKRKRNDI GWIYSEVPAN SAAVYTMNQM QAAPIFVTKD 

        70         80         90        100        110        120 
SFKNNAKLQA IIVNSGNANA CTGNQGMLDA LSMRAKTAER LEIPLDSVAV ASTGIIGDML 

       130        140        150        160        170        180 
PMEKIIAGIN MLEKQMGNAA NFEEAILTTD TFQKQISFQI EIAGKKITMS GVAKGSGMIH 

       190        200        210        220        230        240 
PNMATMLAFI TTDADIPAEL LQKLLKVKVD KTFNQITVDG DTSTNDMVVV MANGCAKNPP 

       250        260        270        280        290        300 
LEEGTAEFEK FADMFQAVTE HLAKSIARDG EGATKLIEVQ VNGATKKEDA RMIAKKIVSS 

       310        320        330        340        350        360 
SLVKTAAFGG DGNWGRIICA IGYSGGRFAP DNITIKIGGI EILHHSSQTI FNQEALDAYL 

       370        380        390 
EEEHIVIEVN LHIGLESGTA WGCDLSYDYV KINACYRT

« Hide

References

[1]"Whole-genome sequence of Listeria welshimeri reveals common steps in genome reduction with Listeria innocua as compared to Listeria monocytogenes."
Hain T., Steinweg C., Kuenne C.T., Billion A., Ghai R., Chatterjee S.S., Domann E., Kaerst U., Goesmann A., Bekel T., Bartels D., Kaiser O., Meyer F., Puehler A., Weisshaar B., Wehland J., Liang C., Dandekar T. expand/collapse author list , Lampidis R., Kreft J., Goebel W., Chakraborty T.
J. Bacteriol. 188:7405-7415(2006) [PubMed: 16936040] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM263198 Genomic DNA. Translation: CAK21021.1.
RefSeqYP_849800.1. NC_008555.1.

3D structure databases

ProteinModelPortalA0AJ39.
SMRA0AJ39. Positions 1-396.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0AJ39.

Protein family/group databases

MEROPST05.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4464968.
GenomeReviewsGene locus lwe1603 in contig AM263198_GR.
KEGGlwe:lwe1603.
NMPDRfig|386043.6.peg.1557.
PATRIC20330351. VBILisWel39304_1610.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1364.
HOGENOMHBG284202.
OMAGRDPNWG.
PhylomeDBA0AJ39.
ProtClustDBPRK05388.

Family and domain databases

HAMAPMF_01106. ArgJ.
[Tree]
InterProIPR002813. Arg_biosynth_ArgJ.
IPR016117. Pept_S58_DmpA/Arg_biosyn_ArgJ.
[Graphical view]
KOK00620.
PANTHERPTHR23100. ArgJ. 1 hit.
PfamPF01960. ArgJ. 1 hit.
[Graphical view]
ProDomPD004193. Arg_biosynth_ArgJ. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56266. Pept_S58_DmpA/Arg_biosyn_ArgJ. 1 hit.
TIGRFAMsTIGR00120. ArgJ. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA0AJ39_LISW6
AccessionPrimary (citable) accession number: A0AJ39
Entry history
Integrated into UniProtKB/TrEMBL: November 28, 2006
Last sequence update: November 28, 2006
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info