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Protein

Probable manganese-dependent inorganic pyrophosphatase

Gene

ppaC

Organism
Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Diphosphate + H2O = 2 phosphate.UniRule annotation

Cofactori

Mn2+UniRule annotationNote: Binds 2 manganese ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi9Manganese 1UniRule annotation1
Metal bindingi13Manganese 1UniRule annotation1
Metal bindingi15Manganese 2UniRule annotation1
Metal bindingi75Manganese 1UniRule annotation1
Metal bindingi75Manganese 2UniRule annotation1
Metal bindingi97Manganese 2UniRule annotation1
Metal bindingi149Manganese 2UniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
LigandManganese, Metal-binding

Enzyme and pathway databases

BioCyciLWEL386043:G1GJF-1489-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Probable manganese-dependent inorganic pyrophosphataseUniRule annotation (EC:3.6.1.1UniRule annotation)
Alternative name(s):
Pyrophosphate phospho-hydrolaseUniRule annotation
Short name:
PPaseUniRule annotation
Gene namesi
Name:ppaCUniRule annotation
Ordered Locus Names:lwe1464
OrganismiListeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)
Taxonomic identifieri386043 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
Proteomesi
  • UP000000779 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000123171 – 308Probable manganese-dependent inorganic pyrophosphataseAdd BLAST308

Proteomic databases

PRIDEiA0AIQ0

Interactioni

Protein-protein interaction databases

STRINGi386043.lwe1464

Structurei

3D structure databases

ProteinModelPortaliA0AIQ0
SMRiA0AIQ0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPase class C family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105E2M Bacteria
COG1227 LUCA
HOGENOMiHOG000223999
KOiK15986
OMAiSTPLECW
OrthoDBiPOG091H00ML

Family and domain databases

Gene3Di3.10.310.20, 1 hit
HAMAPiMF_00207 PPase_C, 1 hit
InterProiView protein in InterPro
IPR001667 DDH_dom
IPR038763 DHH_sf
IPR004097 DHHA2
IPR038222 DHHA2_dom_sf
IPR022934 Mn-dep_inorganic_PyrPase
PfamiView protein in Pfam
PF01368 DHH, 1 hit
PF02833 DHHA2, 1 hit
SMARTiView protein in SMART
SM01131 DHHA2, 1 hit
SUPFAMiSSF64182 SSF64182, 1 hit

Sequencei

Sequence statusi: Complete.

A0AIQ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKTLVFGHK NPDTDTICSA ISYAELKKAQ GADIEAVRLG ELNSETTFVL
60 70 80 90 100
DYFQATAPRL VQTVANEVSE VALVDHNERQ QSANDIDEVT VTAVVDHHRI
110 120 130 140 150
ANFETSDPLY YRAEPVGCTT TILLKMFREN EVEISKTVAG LMLSAIISDT
160 170 180 190 200
LLFQSPTCTE EDKVAAEKLA VIADVDIQTY GMEMLKAGAD VSKKTVAELL
210 220 230 240 250
LDAKEFNMNG NKVEIAQINV VDVNDVLNRR SEVEALMTQN VVDKGLDLYL
260 270 280 290 300
FVITNILTND SIGISIGSKT SVVEEAYGIK FVENQAPLKG VVSRKKQVVP

ILTDTFAK
Length:308
Mass (Da):33,779
Last modified:November 28, 2006 - v1
Checksum:i2A5ECE04C3F966C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM263198 Genomic DNA Translation: CAK20882.1
RefSeqiWP_011702259.1, NC_008555.1

Genome annotation databases

EnsemblBacteriaiCAK20882; CAK20882; lwe1464
KEGGilwe:lwe1464

Similar proteinsi

Entry informationi

Entry nameiPPAC_LISW6
AccessioniPrimary (citable) accession number: A0AIQ0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 28, 2006
Last modified: May 23, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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