ID   A0ADD2_STRA7            Unreviewed;       248 AA.
AC   A0ADD2;
DT   28-NOV-2006, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2006, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   SubName: Full=Putative regulatory protein {ECO:0000313|EMBL:CAJ88488.1};
GN   ORFNames=SAMR0779 {ECO:0000313|EMBL:CAJ88488.1};
OS   Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 /
OS   NBRC 12836 / NRRL B-2516).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=278992 {ECO:0000313|EMBL:CAJ88488.1};
RN   [1] {ECO:0000313|EMBL:CAJ88488.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 23877 {ECO:0000313|EMBL:CAJ88488.1};
RA   Barona-Gomez F., Lautru S., Francou F.X., Leblond P., Pernodet J.L.,
RA   Challis G.L.;
RT   "Multiple biosynthetic and uptake systems mediate siderophore-dependent
RT   iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces
RT   ambofaciens ATCC 23877.";
RL   Microbiology (Mosc.) 152:3355-3366(2006).
RN   [2] {ECO:0000313|EMBL:CAJ88488.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 23877 {ECO:0000313|EMBL:CAJ88488.1};
RX   PubMed=16956972; DOI=10.1093/molbev/msl108;
RA   Choulet F., Aigle B., Gallois A., Mangenot S., Gerbaud C., Truong C.,
RA   Francou F.X., Fourrier C., Guerineau M., Decaris B., Barbe V.,
RA   Pernodet J.L., Leblond P.;
RT   "Evolution of the terminal regions of the Streptomyces linear chromosome.";
RL   Mol. Biol. Evol. 23:2361-2369(2006).
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DR   EMBL; AM238664; CAJ88488.1; -; Genomic_DNA.
DR   RefSeq; WP_053140934.1; NZ_CP012382.1.
DR   AlphaFoldDB; A0ADD2; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR   InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR041347; MftR_C.
DR   PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR   PANTHER; PTHR30055:SF226; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RV1474C; 1.
DR   Pfam; PF17754; TetR_C_14; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   PRINTS; PR00455; HTHTETR.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS01081; HTH_TETR_1; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          21..81
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50977"
FT   DNA_BIND        44..63
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   248 AA;  26993 MW;  9896C8EA19EE8C8A CRC64;
     MSSSSAAPRR GDRADAAGTR PPMREALVSA AFRLFLERGY EQTTVDDIVA LAGVGRRSFF
     RYFPSKEDVV FPDHERCLAD MTAFLAASPG EADPVRRVCD AARLVLRMYA ENPAFSVQRY
     HLTKKVPGLR AYELSVVWRY ERALAEYLRG RLGGLPDGTL RADVIAAAVV AAHNNALRSW
     LRSQGRDDAG AAVDHALRYA QSTFGDVPAA SPAGVTDDVV VVVARRGAPL WQVVREVETA
     FAREGGDG
//