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A0A566

- A0A566_YERPS

UniProt

A0A566 - A0A566_YERPS

Protein

Alanine racemase

Gene

alr

Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (28 Nov 2006)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei34 – 341Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei129 – 1291SubstrateUniRule annotation
    Active sitei254 – 2541Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei302 – 3021Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciYPSE273123:GI1M-406-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    Ordered Locus Names:YPTB0376Imported
    OrganismiYersinia pseudotuberculosis serotype I (strain IP32953)Imported
    Taxonomic identifieri273123 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000001011: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei34 – 341N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi273123.YPTB0376.

    Structurei

    3D structure databases

    ProteinModelPortaliA0A566.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031446.
    KOiK01775.
    OMAiIAINAVE.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0A566-1 [UniParc]FASTAAdd to Basket

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    MKAATAVIDR HALRHNLQQI RRLAPQSRLV AVVKANAYGH GLLAAAHTLQ    50
    DADCYGVARI SEALMLRAGG IVKPILLLEG FFDAEDLPVL VANHIETAVH 100
    SLEQLVALEA ATLSAPINAW MKLDTGMHRL GVRPDQAEAF YQRLSACRNV 150
    IQPVNIMSHF SRADEPEVAA TQQQLACFDA FAAGKPGKQS IAASGGILRW 200
    PQAHRDWVRP GIVLYGVSPF DTPYGRDFGL LPAMTLKSSL IAVREHKAGE 250
    SVGYGGTWVS ERDTRLGVIA IGYGDGYPRS APSGTPVWLN GREVSIVGRV 300
    SMDMISIDLG PESTDKVGDE ALMWGAELPV ERVAACTGIS AYELITNLTS 350
    RVAMEYLGE 359
    Length:359
    Mass (Da):38,733
    Last modified:November 28, 2006 - v1
    Checksum:iAD9D0AB234504D32
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX936398 Genomic DNA. Translation: CAH19616.1.
    RefSeqiWP_011191596.1. NC_006155.1.
    YP_068921.1. NC_006155.1.

    Genome annotation databases

    EnsemblBacteriaiCAH19616; CAH19616; YPTB0376.
    GeneIDi2955187.
    KEGGiyps:YPTB0376.
    PATRICi18638915. VBIYerPse22266_0557.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX936398 Genomic DNA. Translation: CAH19616.1 .
    RefSeqi WP_011191596.1. NC_006155.1.
    YP_068921.1. NC_006155.1.

    3D structure databases

    ProteinModelPortali A0A566.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 273123.YPTB0376.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAH19616 ; CAH19616 ; YPTB0376 .
    GeneIDi 2955187.
    KEGGi yps:YPTB0376.
    PATRICi 18638915. VBIYerPse22266_0557.

    Phylogenomic databases

    HOGENOMi HOG000031446.
    KOi K01775.
    OMAi IAINAVE.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci YPSE273123:GI1M-406-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IP32953Imported.

    Entry informationi

    Entry nameiA0A566_YERPS
    AccessioniPrimary (citable) accession number: A0A566
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 28, 2006
    Last sequence update: November 28, 2006
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3