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A0A566

- A0A566_YERPS

UniProt

A0A566 - A0A566_YERPS

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Protein
Alanine racemase
Gene
alr, YPTB0376
Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei34 – 341Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei129 – 1291Substrate By similarityUniRule annotation
Active sitei254 – 2541Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei302 – 3021Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciYPSE273123:GI1M-406-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:YPTB0376Imported
OrganismiYersinia pseudotuberculosis serotype I (strain IP32953)Imported
Taxonomic identifieri273123 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000001011: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei34 – 341N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi273123.YPTB0376.

Structurei

3D structure databases

ProteinModelPortaliA0A566.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000031446.
KOiK01775.
OMAiIAINAVE.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0A566-1 [UniParc]FASTAAdd to Basket

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MKAATAVIDR HALRHNLQQI RRLAPQSRLV AVVKANAYGH GLLAAAHTLQ    50
DADCYGVARI SEALMLRAGG IVKPILLLEG FFDAEDLPVL VANHIETAVH 100
SLEQLVALEA ATLSAPINAW MKLDTGMHRL GVRPDQAEAF YQRLSACRNV 150
IQPVNIMSHF SRADEPEVAA TQQQLACFDA FAAGKPGKQS IAASGGILRW 200
PQAHRDWVRP GIVLYGVSPF DTPYGRDFGL LPAMTLKSSL IAVREHKAGE 250
SVGYGGTWVS ERDTRLGVIA IGYGDGYPRS APSGTPVWLN GREVSIVGRV 300
SMDMISIDLG PESTDKVGDE ALMWGAELPV ERVAACTGIS AYELITNLTS 350
RVAMEYLGE 359
Length:359
Mass (Da):38,733
Last modified:November 28, 2006 - v1
Checksum:iAD9D0AB234504D32
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX936398 Genomic DNA. Translation: CAH19616.1.
RefSeqiWP_011191596.1. NC_006155.1.
YP_068921.1. NC_006155.1.

Genome annotation databases

EnsemblBacteriaiCAH19616; CAH19616; YPTB0376.
GeneIDi2955187.
KEGGiyps:YPTB0376.
PATRICi18638915. VBIYerPse22266_0557.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX936398 Genomic DNA. Translation: CAH19616.1 .
RefSeqi WP_011191596.1. NC_006155.1.
YP_068921.1. NC_006155.1.

3D structure databases

ProteinModelPortali A0A566.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273123.YPTB0376.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAH19616 ; CAH19616 ; YPTB0376 .
GeneIDi 2955187.
KEGGi yps:YPTB0376.
PATRICi 18638915. VBIYerPse22266_0557.

Phylogenomic databases

HOGENOMi HOG000031446.
KOi K01775.
OMAi IAINAVE.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci YPSE273123:GI1M-406-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IP32953.

Entry informationi

Entry nameiA0A566_YERPS
AccessioniPrimary (citable) accession number: A0A566
Entry historyi
Integrated into UniProtKB/TrEMBL: November 28, 2006
Last sequence update: November 28, 2006
Last modified: September 3, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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