A0A502 (A0A502_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CC-chemokine receptor EMBL AAC23944.1

Gene names

Name:

CCR-5 EMBL AAC23944.1

Organism

Homo sapiens (Human) EMBL AAC23944.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	215 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. RuleBase RU000688

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS000355
Molecular function	G-protein coupled receptor RuleBase RU000688 SAAS SAAS000355 Receptor Transducer
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	C-C chemokine receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0A502 [UniParc]. Last modified November 28, 2006. Version 1. Checksum: 3C9146C76BA416F7	FASTA	215	23,946
	10 20 30 40 50 60 MDYQVSSPIY DINYYTSEPC QKINVKQIAA RLLPPLYSLV FIFGFVGNML VILILINCKR 70 80 90 100 110 120 LKSMTDIYLL NLAISDLFFL LTVPFWAHYA AAQWDFGNTM CQLLTGLYFI GFFSGIFFII 130 140 150 160 170 180 LLTIDRYLAV VHAVFALKAR TVTFGVVTSV ITWVVAVFAS LPGIIFTRSQ KEGLHYTCSS 190 200 210 HFPYIKDSHL GAGPAAACHG HLLLGNPKNS ASVSK

References

[1]	"Genomic Organization and Functional Characterization of the Complete Transcription Unit for the Chemokine Receptor CCR-5, a Major Entry Co-Receptor for HIV-1." Tse L., Ehrenberg P.K., Chang G., Michael N.L. Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF009962 Genomic DNA. Translation: AAC23944.1.
IPI	IPI00743929.
UniGene	Hs.450802.
3D structure databases
ProteinModelPortal	A0A502.
ModBase	Search...
Protein-protein interaction databases
STRING	A0A502.
Protein family/group databases
GPCRDB	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG079402.
Family and domain databases
InterPro	IPR000276. 7TM_GPCR_Rhodpsn. IPR002240. Chemokine_CCR5. IPR000355. Chemokine_rcpt. IPR017452. GPCR_Rhodpsn_supfam. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. [Graphical view]
PRINTS	PR00657. CCCHEMOKINER. PR01110. CHEMOKINER5. PR00237. GPCRRHODOPSN.
PROSITE	PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0A502_HUMAN

Accession

Primary (citable) accession number: A0A502

Entry history

Integrated into UniProtKB/TrEMBL:	November 28, 2006
Last sequence update:	November 28, 2006
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.