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Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotationSAAS annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseUniRule annotationSAAS annotationImported
Biological processProtein biosynthesisUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotationSAAS annotation (EC:2.1.2.9UniRule annotationSAAS annotation)
Gene namesi
Name:fmtUniRule annotation
ORF Names:CXQ84_20895Imported
OrganismiBurkholderia pseudomallei (Pseudomonas pseudomallei)Imported
Taxonomic identifieri28450 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
Proteomesi
  • UP000233327 Componenti: Chromosome 1

Structurei

3D structure databases

SMRiA0A2K9D5F2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 192Formyl_trans_NInterPro annotationAdd BLAST186
Domaini216 – 313Formyl_trans_CInterPro annotationAdd BLAST98

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni121 – 124Tetrahydrofolate (THF) bindingUniRule annotation4

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di3.10.25.10, 1 hit
HAMAPiMF_00182 Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794 Fmt
IPR005793 Formyl_trans_C
IPR037022 Formyl_trans_C_sf
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR011034 Formyl_transferase-like_C_sf
IPR001555 GART_AS
PfamiView protein in Pfam
PF02911 Formyl_trans_C, 1 hit
PF00551 Formyl_trans_N, 1 hit
SUPFAMiSSF50486 SSF50486, 1 hit
SSF53328 SSF53328, 1 hit
TIGRFAMsiTIGR00460 fmt, 1 hit
PROSITEiView protein in PROSITE
PS00373 GART, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2K9D5F2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHSLRVIFA GTPEFAAAAL AAIHEAGFPV PLVLTQPDRP AGRGMKLQAS
60 70 80 90 100
AVKRYAFERG MAVAQPPSLR RAGKYPAEAV AALDLLHATP HDVMVVAAYG
110 120 130 140 150
LLLPQEVLEL PRHGCINIHA SLLPRWRGAA PIHRAIEAGD AETGVTLMQM
160 170 180 190 200
DAGLDTGAML HEARVAIAPD DTTATLHDKL AAAGARLIVD ALVELERTGA
210 220 230 240 250
LAATPQPADG VTYAEKIGKH EAALDWRKPA AALARQVRAF DPFPGGAGTL
260 270 280 290 300
DGATLKLWAA DAVPGRDDAA PGTIVDIGPD GVVIACGEGA LRVTQLQKPG
310 320
GKRLPAREFL AGAPLAVGQR FAPADAA
Length:327
Mass (Da):33,948
Last modified:April 25, 2018 - v1
Checksum:i2F1D0BB7E1DF9ECF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP025264 Genomic DNA Translation: AUG22727.1
RefSeqiWP_004200737.1, NZ_LXCR01000109.1

Similar proteinsi

Entry informationi

Entry nameiA0A2K9D5F2_BURPE
AccessioniPrimary (citable) accession number: A0A2K9D5F2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 25, 2018
Last sequence update: April 25, 2018
Last modified: June 20, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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