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Protein
Submitted name:

Glutamate ionotropic receptor NMDA type subunit 3A

Gene

GRIN3A

Organism
Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamate ionotropic receptor NMDA type subunit 3AImported
Gene namesi
Name:GRIN3AImported
OrganismiRhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti)Imported
Taxonomic identifieri61621 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeColobinaeRhinopithecus
Proteomesi
  • UP000233180 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei675 – 695HelicalSequence analysisAdd BLAST21
Transmembranei716 – 734HelicalSequence analysisAdd BLAST19
Transmembranei746 – 769HelicalSequence analysisAdd BLAST24
Transmembranei934 – 956HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_501432373027 – 1139Sequence analysisAdd BLAST1113

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini557 – 622Lig_chan-Glu_bdInterPro annotationAdd BLAST66
Domaini565 – 910PBPeInterPro annotationAdd BLAST346

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1065 – 1099Sequence analysisAdd BLAST35
Coiled coili1103 – 1123Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. [View classification]SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00910000143978

Family and domain databases

InterProiView protein in InterPro
IPR019594 Glu/Gly-bd
IPR001508 Iono_rcpt_met
IPR001320 Iontro_rcpt
IPR028082 Peripla_BP_I
PfamiView protein in Pfam
PF00060 Lig_chan, 1 hit
PF10613 Lig_chan-Glu_bd, 1 hit
PRINTSiPR00177 NMDARECEPTOR
SMARTiView protein in SMART
SM00918 Lig_chan-Glu_bd, 1 hit
SM00079 PBPe, 1 hit
SUPFAMiSSF53822 SSF53822, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2K6L9D6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRLSLWWLL SRVCLLLPPP CALVLAGVPG SSSHPQPCQI LKRIGHAVRV
60 70 80 90 100
GAVHLQPWST APRAASRAPD GSPAGSQRDE PEPGTRRSPA PSPGARWLGS
110 120 130 140 150
TLHGRGPPGS PKPGKGARAK TLWPRDALLF AVDNLNRVEG LLPYNLSLEV
160 170 180 190 200
VMAIEAGLGD LPLLPFSSPS SPWSSDPFSF LQSVCHTVVV QGVSALLAFP
210 220 230 240 250
QSQGEMMELD LVSLVLHIPV ISIVRHEFPR ESQNPLHLQL SLENSLSSDA
260 270 280 290 300
DVTVSILTMN NWYNFSLLLC QEDWNITDFL LLTQNNSKFH LGSIINITAN
310 320 330 340 350
LPSTQDLLSF LQIQLESIKN STPTVVMFGC DMESIRRIFK ITAQFGVMPP
360 370 380 390 400
ELRWVLGDSQ NVEELRTEGL PLGLIAHGKT TQSVFEYYVQ DAMELVARAV
410 420 430 440 450
ATATMIQPEL ALIPSTMNCM EVETTNLTSG QYLSRFLANT TFRGLSGSIR
460 470 480 490 500
VKGSTIISSE NNFFIWNLQH DPMGKPMWTR LGSWQGGKIV MDYGIWPEQA
510 520 530 540 550
QRHKTHFQHP SKLHLRVVTL IEHPFVFTRE VDDEGLCPAG QLCLDPMTND
560 570 580 590 600
ASTLDSLFSS LHSSNDTVPI KFKKCCYGYC IDLLEKIAED MNFDFDLYIV
610 620 630 640 650
GDGKYGAWKN GHWTGLVGDL LSGTAHMAVT SFSINTARSQ VIDFTSPFFS
660 670 680 690 700
TSLGILVRTR DTAAPIGAFM WPLHWTMWLG IFVALHITAI FLTLYEWKSP
710 720 730 740 750
FGLTPKGRNR SKVFSFSSAL NVCYALLFGR TVAIKPPKCW TGRFLMNLWA
760 770 780 790 800
IFCMFCLSTY TANLAAVMVG EKIYEELSGI HDPKLHHPSQ GFRFGTVRES
810 820 830 840 850
SAEDYVRQSF PEMHEYMRRY NVPATPDGVQ YLKNDPEKLD AFIMDKALLD
860 870 880 890 900
YEVSIDADCK LLTVGKPFAI EGYGIGLPPN SPLTSNISEL ISQYKSHGFM
910 920 930 940 950
DVLHDKWYKV VPCGKRSFAV TETLQMGIKH FSGLFVLLCI GFGLSILTTI
960 970 980 990 1000
GEHIVYRLLL PRIKNKSKLQ YWLHTSQRLH RALNTSFVEE KQQHFKTKRV
1010 1020 1030 1040 1050
EKRSNVGPRQ LTVWNTSNLS HDNRRKYIFS DEEGQNQLGI RIHQDIPLPP
1060 1070 1080 1090 1100
RRRELPASLT TNGKADSLNV SRNSVMQELS ELEKQIQVIR QELQLAVSRK
1110 1120 1130
TELEEYQRTS RTFQRRNTRY TEKTQSSGIV KWLHLRQTF
Length:1,139
Mass (Da):128,129
Last modified:March 28, 2018 - v1
Checksum:iDB131AF1A6347C1C
GO

Sequence databases

RefSeqiXP_017739790.1, XM_017884301.1

Genome annotation databases

EnsembliENSRBIT00000044005; ENSRBIP00000020127; ENSRBIG00000034056
GeneIDi108537157

Similar proteinsi

Entry informationi

Entry nameiA0A2K6L9D6_RHIBE
AccessioniPrimary (citable) accession number: A0A2K6L9D6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: June 20, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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