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Protein

EEF1A lysine methyltransferase 1

Gene

n6amt2

Organism
Austrofundulus limnaeus
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.UniRule annotation

Caution

Was originally thought to be an N6-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
EEF1A lysine methyltransferase 1UniRule annotation (EC:2.1.1.-UniRule annotation)
Alternative name(s):
N(6)-adenine-specific DNA methyltransferase 2UniRule annotation
Protein-lysine N-methyltransferase N6AMT2UniRule annotation
Gene namesi
Name:n6amt2Imported
Synonyms:EEF1AKMT1UniRule annotation, N6AMT2UniRule annotation
OrganismiAustrofundulus limnaeusImported
Taxonomic identifieri52670 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesRivulidaeAustrofundulus
Proteomesi
  • UP000192220 Componenti: Genome assembly

Subcellular locationi

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.UniRule annotation

Family and domain databases

HAMAPiMF_03187 Methyltr_EFM5, 1 hit
InterProiView protein in InterPro
IPR002052 DNA_methylase_N6_adenine_CS
IPR019369 Efm5/EEF1AKMT1
PROSITEiView protein in PROSITE
PS00092 N6_MTASE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2I4CVE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDCDDDDDD VPTLSAHTLA ALQEFYKETG TGPDHGTTPS DPFAVGAVEE
60 70 80 90 100
DWRMSQFWYS DETAAQLAEE VLREAGEGGR VACVSAPSVY QKLKQGGSDR
110 120 130 140 150
VSAVVFEYDR RFSAYGQDFI FYDYNEPLSL PCSVAPRSFD MVLADPPYLS
160 170 180 190 200
QECLSKVAQT IRFLSKDKVL LCTGAIMENL AKELLDVKMC SFVPKHNRNL
210
SNEFRCFVNY PSRLLSC
Length:217
Mass (Da):24,234
Last modified:February 28, 2018 - v1
Checksum:i48A63711DE05C51A
GO

Sequence databases

RefSeqiXP_013883947.1, XM_014028493.1

Genome annotation databases

GeneIDi106532447

Similar proteinsi

Entry informationi

Entry nameiA0A2I4CVE2_9TELE
AccessioniPrimary (citable) accession number: A0A2I4CVE2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: May 23, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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