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Protein

Katanin p60 ATPase-containing subunit A-like 2

Gene

katnal2

Organism
Austrofundulus limnaeus
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi274 – 281ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Katanin p60 ATPase-containing subunit A-like 2UniRule annotation (EC:3.6.4.3UniRule annotation)
Short name:
Katanin p60 subunit A-like 2UniRule annotation
Alternative name(s):
p60 katanin-like 2UniRule annotation
Gene namesi
Name:katnal2Imported
Synonyms:KATNAL2UniRule annotation
OrganismiAustrofundulus limnaeusImported
Taxonomic identifieri52670 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesRivulidaeAustrofundulus
Proteomesi
  • UP000192220 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation, MicrotubuleUniRule annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 57LisHInterPro annotationAdd BLAST33

Sequence similaritiesi

Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.UniRule annotation

Family and domain databases

HAMAPiMF_03025 Katanin_p60_AL2, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR027497 Katanin_p60_AL2
IPR006594 LisH
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00004 AAA, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50896 LISH, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2I4AR70-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELSYQSMKI AHQAREAEEL RTEKRKKNLL VLIYHHLLGQ GYLAAAVALD
60 70 80 90 100
QETNGAVKKF EVCDNIDLEM MLIEYESYHY VKFQKYPKLV RRAAEPDENK
110 120 130 140 150
PIKNSGIKKR SCSAVKPLPK IVSPSVPKSG NAAKRTAPSV YENVVSVVPE
160 170 180 190 200
SSGFGLNISS IKNGPAGDSA MGRKMSDGKA TIHDAVRGSG FHSDHMERLL
210 220 230 240 250
KPLSGFSGMS GELKELAXXI SRDIYLHSPN VRWEDIIGLE DAKRLVKEAV
260 270 280 290 300
XCPIKYPWLF TGVLSPWKGL LLYGPPGTGK TLLAKAVATE CKTTFFNISA
310 320 330 340 350
SSIVSKWRGD SEKLVRVLFE LARYHAPSTI FLDELESVMG QRGTSLGGEH
360 370 380 390 400
EGSRRMKTEL LVQMDGLAKS EDLVFVLAAS NLPWELDHAM LRRLEKRILV
410 420 430 440 450
NLPSPAARQA MMSHWLPPLS NIGELELRTE LDYETLAERM EGYSGSDIRL
460 470 480 490 500
VCKEAAMKRV RKLIKALESH QNNADGPVIQ LGTVTTADFT EAISRTKPSA
510
RNLMDRYTAW DREYESV
Length:517
Mass (Da):57,637
Last modified:February 28, 2018 - v1
Checksum:i6AACA6F120AD31F5
GO

Sequence databases

RefSeqiXP_013857983.1, XM_014002529.1

Genome annotation databases

GeneIDi106513605

Entry informationi

Entry nameiA0A2I4AR70_9TELE
AccessioniPrimary (citable) accession number: A0A2I4AR70
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: May 23, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health