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Protein
Submitted name:

Fibulin 2

Gene

FBLN2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Fibulin 2Imported
Gene namesi
Name:FBLN2Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 3

Organism-specific databases

VGNCiVGNC:1815 FBLN2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_501413954328 – 1231Sequence analysisAdd BLAST1204

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini445 – 480Anaphylatoxin-likeInterPro annotationAdd BLAST36
Domaini488 – 519Anaphylatoxin-likeInterPro annotationAdd BLAST32
Domaini521 – 553Anaphylatoxin-likeInterPro annotationAdd BLAST33
Domaini604 – 645EGF-likeInterPro annotationAdd BLAST42
Domaini905 – 943EGF-likeInterPro annotationAdd BLAST39
Domaini948 – 989EGF-likeInterPro annotationAdd BLAST42
Domaini990 – 1028EGF-likeInterPro annotationAdd BLAST39

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili270 – 290Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000118806

Family and domain databases

InterProiView protein in InterPro
IPR000020 Anaphylatoxin/fibulin
IPR026823 cEGF
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR037286 Fibulin-2
IPR009030 Growth_fac_rcpt_cys_sf
PANTHERiPTHR44887 PTHR44887, 1 hit
PfamiView protein in Pfam
PF01821 ANATO, 1 hit
PF12662 cEGF, 2 hits
PF07645 EGF_CA, 6 hits
SMARTiView protein in SMART
SM00104 ANATO, 3 hits
SM00181 EGF, 12 hits
SM00179 EGF_CA, 10 hits
SUPFAMiSSF57184 SSF57184, 6 hits
PROSITEiView protein in PROSITE
PS01177 ANAPHYLATOXIN_1, 1 hit
PS01178 ANAPHYLATOXIN_2, 3 hits
PS00010 ASX_HYDROXYL, 4 hits
PS01186 EGF_2, 3 hits
PS50026 EGF_3, 4 hits
PS01187 EGF_CA, 3 hits

Sequencei

Sequence statusi: Complete.

A0A2I3TFQ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLLWEPAGA WLALGLALAL GPSVAAAAPR QDCTGVECPP LENCIEEALE
60 70 80 90 100
PGACCATCVQ QGCACEGYQY YDCLQGGFVR GRVPAGQSYF VDFGSTECSC
110 120 130 140 150
PPGGGKISCQ FMLCPELPPN CIEAVVVADS CPQCGQVGCV HAGRKYAAGH
160 170 180 190 200
TVHLPPCRAC HCPDAGGELI CYQLPSCHGN FSDAEEGDPE RHYEDPYSYD
210 220 230 240 250
QEVAEVEAAA ALGSEVQAGA VQAGAGGPPA ALGGESQPLS TIQAPPWPAA
260 270 280 290 300
LPRPTAAAAL GPPAPVQAKA RRVTEDSEEE EEEEEEREEM AVTEQLAAGG
310 320 330 340 350
HRGLDGLPTT APAGPSLPIQ EERAEAGARA EAGARPEENL IPDAQATSRS
360 370 380 390 400
TGPEGVTHAP GLGKAALVPT QAVPGSPRDP VKPSPHTILS TSLPDAAWIP
410 420 430 440 450
PTREVPRKPQ VLPHSHVEED TDPNSLHSIP RSSPEGSTKD LIETCCAAGQ
460 470 480 490 500
QWAIDNDECL EIPESGTEDN VCRTAQRHCC VSYLQEKSCM AGVLGAKEGE
510 520 530 540 550
TCGAEDNDSC GISLYKQCCD CCGLGLRVRA EGQSCESNPN LGYPCNHVML
560 570 580 590 600
SCCEGEEPLI VPEVRRPPEP AAAPRRVSEA EMAGREALSL GTEAELPNSL
610 620 630 640 650
PGDDQDECLL LPGELCQHLC INTVGSYHCA CFPGFSLQDD GRTCRPEGHP
660 670 680 690 700
PQPEAPQEPA LKSEFSQVAS NTIPLPLPQP NTCKDNGPCK QVCSTVGGSA
710 720 730 740 750
ICSCFPGYAI MADGVSCEDQ DECLMGAHDC SRRQFCVNTL GSFYCVNHTV
760 770 780 790 800
LCADGYILNA HRKCVDINEC VTDLHTCSRG EHCVNTLGSF HCDKALTCEP
810 820 830 840 850
GYALKDGECE DVDECAMGTH TCQPGFLCQN TKGSFYCQAR QRCMDGFLQD
860 870 880 890 900
PEGNCVDINE CTSLSEPCRP GFSCINTVGS YTCQRNPLIC ARGYHASDDG
910 920 930 940 950
AKCVDVNECE TGVHRCGEGQ VCHNLPGSYR CDCKAGFQRD AFGRGCIDVN
960 970 980 990 1000
ECWASPGRLC QHTCENTLGS YRCSCASGFL LAADGKRCED VNECEAQRCS
1010 1020 1030 1040 1050
QECANIYGSY QCYCRQGYQL AEDGHTCTDI DECAQGAGIL CTFRCLNVPG
1060 1070 1080 1090 1100
SYQCACPEQG YTMTANGRSC KDVDECALGT HNCSEAETCH NIQGSFRCLR
1110 1120 1130 1140 1150
FECPPNYVQV SKTKCERTTC HDFLECQNSP ARITHYQLNF QTGLLVPAHI
1160 1170 1180 1190 1200
FRIGPAPAFT GDTIALNIIK GNEEGYFGTR RLNAYTGVVY LQRAVLEPRD
1210 1220 1230
FALDVEMKLW RQGSVTTFLA KMHIFFTTFA L
Length:1,231
Mass (Da):131,833
Last modified:February 28, 2018 - v1
Checksum:iAECEDA29CED5758B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04000099 Genomic DNA No translation available.
AACZ04000100 Genomic DNA No translation available.
RefSeqiXP_016796012.1, XM_016940523.1
XP_016796013.1, XM_016940524.1

Genome annotation databases

EnsembliENSPTRT00000094991; ENSPTRP00000088075; ENSPTRG00000014642
GeneIDi460192

Similar proteinsi

Entry informationi

Entry nameiA0A2I3TFQ9_PANTR
AccessioniPrimary (citable) accession number: A0A2I3TFQ9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: May 23, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health