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Protein
Submitted name:

MDM2 proto-oncogene

Gene

MDM2

Organism
Papio anubis (Olive baboon)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
MDM2 proto-oncogeneImported
Gene namesi
Name:MDM2Imported
OrganismiPapio anubis (Olive baboon)Imported
Taxonomic identifieri9555 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaePapio
Proteomesi
  • UP000028761 Componenti: Chromosome 11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini247 – 276RanBP2-typeInterPro annotationAdd BLAST30
Domaini386 – 427RING-typeInterPro annotationAdd BLAST42

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili165 – 185Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00530000063539

Family and domain databases

Gene3Di1.10.245.10, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR028340 Mdm2
IPR015459 MDM2_E3_ligase
IPR016495 p53_neg-reg_MDM_2/4
IPR036885 SWIB_MDM2_dom_sf
IPR003121 SWIB_MDM2_domain
IPR001876 Znf_RanBP2
IPR036443 Znf_RanBP2_sf
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR13844:SF15 PTHR13844:SF15, 2 hits
PfamiView protein in Pfam
PF02201 SWIB, 1 hit
PF00641 zf-RanBP, 1 hit
PIRSFiPIRSF500700 MDM2, 2 hits
PIRSF006748 p53_MDM_2/4, 2 hits
SUPFAMiSSF47592 SSF47592, 1 hit
SSF90209 SSF90209, 1 hit
PROSITEiView protein in PROSITE
PS01358 ZF_RANBP2_1, 1 hit
PS50199 ZF_RANBP2_2, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2I3NF10-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCNTNMSVPT DGAVTTSQIP ASEQETLVRP KPLLLKLLKS VGAQKDTYTM
60 70 80 90 100
KEVLFYLGQY IMTKRLYDEK QQHIVYCSND LLGDLFGVPS FSVKEHRKIY
110 120 130 140 150
TMIYRNLVVV NQQESSDSGT SVSENRCHLE GGSDQKDLVQ ELQEEKPSSS
160 170 180 190 200
HLVSRPSTSS RRRAISETEE NSDELSGERQ RKRHKSDSIS LSFDESLALC
210 220 230 240 250
VIREICCERS SSSESTGTPS NPVYRVTVYQ AGESDTDSFE EDPEISLADY
260 270 280 290 300
WKCTSCNEMN PPLPSHCNRC WALRENWLPE DKGKDKGEIS EKAKLENSTQ
310 320 330 340 350
AEEGFDVPDC KKTIVNDSKE SCVEENDDKI TQASQSQESE DYSQPSTSSS
360 370 380 390 400
IIYSSQEDVK EFEREETQDK EESVESSLPL NAIEPCVICQ GRPKNGCIVH
410 420 430
GKTGHLMACF TCAKKLKKRN KPCPVCRQPI QMIVLTYFP
Length:439
Mass (Da):49,435
Last modified:February 28, 2018 - v1
Checksum:iBC1D1C119CB354E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AHZZ02002425 Genomic DNA No translation available.
AHZZ02002426 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSPANT00000032053; ENSPANP00000046583; ENSPANG00000005563

Similar proteinsi

Entry informationi

Entry nameiA0A2I3NF10_PAPAN
AccessioniPrimary (citable) accession number: A0A2I3NF10
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: April 25, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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