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Protein

Phosphoglycerate kinase

Gene

D915_03906

Organism
Fasciola hepatica (Liver fluke)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), Glyceraldehyde-3-phosphate dehydrogenase (D915_13480)
  2. Phosphoglycerate kinase (D915_03905), Phosphoglycerate kinase, Phosphoglycerate kinase (D915_03906), Phosphoglycerate kinase
  3. no protein annotated in this organism
  4. Enolase (ENO)
  5. Pyruvate kinase (D915_13877), Pyruvate kinase (D915_02241)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
ORF Names:D915_03906Imported
OrganismiFasciola hepatica (Liver fluke)Imported
Taxonomic identifieri6192 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaPlagiorchiidaEchinostomataEchinostomatoideaFasciolidaeFasciola

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
InterProiView protein in InterPro
IPR001576. Phosphoglycerate_kinase.
IPR015824. Phosphoglycerate_kinase_N.
IPR036043. Phosphoglycerate_kinase_sf.
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiView protein in Pfam
PF00162. PGK. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A2H1CMG4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDKVNELII TGGMAFTFLK KLHNMKIGKS LFDEPGAAIV DEVMALAKQK
60 70 80 90 100
KVEIHLPVDF VTGSKFGDDA TVGSATVESG IPDDYMGLDC GPKTMEKFRA
110 120 130 140 150
VILRAKTIVW NGPMGVFEME KFAGGTKAAM DAVVEATKNG ATTIIGGGDT
160 170 180 190
ATCCAKWKTE DKVSHVSTGG GASLELLEGK ELPGVVALTN A
Length:191
Mass (Da):20,083
Last modified:January 31, 2018 - v1
Checksum:iD1AFDBB3DC6502AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KZ428915 Genomic DNA. Translation: PIS88655.1.

Similar proteinsi

Entry informationi

Entry nameiA0A2H1CMG4_FASHE
AccessioniPrimary (citable) accession number: A0A2H1CMG4
Entry historyiIntegrated into UniProtKB/TrEMBL: January 31, 2018
Last sequence update: January 31, 2018
Last modified: March 28, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)