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Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Iodobacter sp. BJB302
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotationSAAS annotation

Pathwayi: NAD(+) biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Nicotinate phosphoribosyltransferase (pncB)
This subpathway is part of the pathway NAD(+) biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate, the pathway NAD(+) biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseImported, LigaseUniRule annotationSAAS annotation, Transferase
Biological processPyridine nucleotide biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00253; UER00457

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotationSAAS annotation (EC:6.3.4.21UniRule annotationSAAS annotation)
Short name:
NAPRTaseUniRule annotation
Gene namesi
Name:pncBUniRule annotationImported
ORF Names:CSQ88_07825Imported
OrganismiIodobacter sp. BJB302Imported
Taxonomic identifieri1506510 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesChromobacteriaceaeIodobacter
Proteomesi
  • UP000224670 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_00570 NAPRTase, 1 hit
InterProiView protein in InterPro
IPR006406 Nic_PRibTrfase
IPR007229 Nic_PRibTrfase-Fam
IPR036068 Nicotinate_pribotase_like_C
PANTHERiPTHR11098 PTHR11098, 1 hit
PfamiView protein in Pfam
PF04095 NAPRTase, 1 hit
PIRSFiPIRSF000484 NAPRT, 1 hit
SUPFAMiSSF51690 SSF51690, 1 hit
TIGRFAMsiTIGR01514 NAPRTase, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2G3JCN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGFMPVIES LLDTDLYKFT MMQEILHHQP ETQAIYAFKC RNTPVLPLAL
60 70 80 90 100
LQNEIEAQLD HLCSLRFSES ELAYLGKLRF IKSDFVDFLR LFQLQRRFIS
110 120 130 140 150
ISVSETDPDL LDIRVAGPML HCMLFEIYVL SIVNEVYFRQ FPAGPALATG
160 170 180 190 200
RAHLQAKLAT LKNLSQQAMP ANPFVFFDFG TRRRFSRVWH AEMVGLLVKE
210 220 230 240 250
ASPYFRGTSN VLLAMQYGVT PIGTMAHEYM QAFQCFGSRL RDFQTNALEH
260 270 280 290 300
WVREYRGDLG IALTDVVGTD AFLRDFDLYF CKLFDGLRHD SGDPFEWGEK
310 320 330 340 350
VIAHYKKMNI DYGTKQLVFS DGLTLDKSIA LYRHFAPRTR TGFGIGTHLS
360 370 380 390 400
NDCGQDPLQI VMKLVSCNGQ PVAKVSDTAG KGMCEDENFL NYLCDVFQIS

RQ
Length:402
Mass (Da):45,950
Last modified:January 31, 2018 - v1
Checksum:i67173433EA1F9F48
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
PDZG01000017 Genomic DNA Translation: PHV02305.1

Similar proteinsi

Entry informationi

Entry nameiA0A2G3JCN8_9NEIS
AccessioniPrimary (citable) accession number: A0A2G3JCN8
Entry historyiIntegrated into UniProtKB/TrEMBL: January 31, 2018
Last sequence update: January 31, 2018
Last modified: March 28, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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