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Protein

Transaldolase

Gene

tal

Organism
Actinobacillus pleuropneumoniae (Haemophilus pleuropneumoniae)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotationSAAS annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotationSAAS annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei131Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationSAAS annotationImported
Biological processPentose shuntUniRule annotationSAAS annotation
LigandSchiff baseUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414

Names & Taxonomyi

Protein namesi
Recommended name:
TransaldolaseUniRule annotationSAAS annotation (EC:2.2.1.2UniRule annotationSAAS annotation)
Gene namesi
Name:talUniRule annotationImported
ORF Names:CHY23_01225Imported
OrganismiActinobacillus pleuropneumoniae (Haemophilus pleuropneumoniae)Imported
Taxonomic identifieri715 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.SAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 1 subfamily.UniRule annotationSAAS annotation

Family and domain databases

CDDicd00957 Transaldolase_TalAB, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00492 Transaldolase_1, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR001585 TAL/FSA
IPR004730 Transaldolase_1
IPR018225 Transaldolase_AS
PANTHERiPTHR10683 PTHR10683, 1 hit
PTHR10683:SF20 PTHR10683:SF20, 1 hit
PfamiView protein in Pfam
PF00923 TAL_FSA, 1 hit
TIGRFAMsiTIGR00874 talAB, 1 hit
PROSITEiView protein in PROSITE
PS01054 TRANSALDOLASE_1, 1 hit
PS00958 TRANSALDOLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A223MEH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQLDALREM TVVVADTGDI EAIKQYQPQD ATTNPSLILS ASALPQYASL
60 70 80 90 100
IDDAVAYAKA RSDDKAQQLI DAEDKLAVNI GLEILKIVPG RISTEVDARL
110 120 130 140 150
SYDTKATIEK ARQIMKLYND AGISNDRILI KIASTWQGIR AAEVLEKEGI
160 170 180 190 200
NCNLTLLFSQ AQARACAEAG VYLISPFVGR ILDWYKAAEK KEYAPAEDPG
210 220 230 240 250
VISVTNIYNY YKQYGYQTVV MGASFRNVGE ITEIAGCDRL TIAPPLLKEL
260 270 280 290 300
AESNAPLVRK LEYKGEVKTR PAPLTEAEFY WQHNQDPMAV EKLAEGIRKF
310
AVDIEKLEAM LAAKL
Length:315
Mass (Da):34,810
Last modified:October 25, 2017 - v1
Checksum:iB5DB8EB81002E6DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP022715 Genomic DNA Translation: ASU15982.1

Similar proteinsi

Entry informationi

Entry nameiA0A223MEH1_ACTPL
AccessioniPrimary (citable) accession number: A0A223MEH1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 25, 2017
Last sequence update: October 25, 2017
Last modified: March 28, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
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Main funding by: National Institutes of Health