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Protein
Submitted name:

Dual glucagon-like peptide 1 receptor/glucagon receptor

Gene

gcgrb

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Dual glucagon-like peptide 1 receptor/glucagon receptorImported
Gene namesi
Name:gcgrbImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei129 – 150HelicalSequence analysisAdd BLAST22
Transmembranei251 – 270HelicalSequence analysisAdd BLAST20
Transmembranei290 – 313HelicalSequence analysisAdd BLAST24
Transmembranei334 – 356HelicalSequence analysisAdd BLAST23
Transmembranei368 – 392HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 114G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST78
Domaini127 – 393G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST267

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di4.10.1240.10. 1 hit.
InterProiView protein in InterPro
IPR017981. GPCR_2-like.
IPR036445. GPCR_2_extracell_dom_sf.
IPR001879. GPCR_2_extracellular_dom.
IPR001749. GPCR_2_GIP_rcpt.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
PfamiView protein in Pfam
PF00002. 7tm_2. 1 hit.
PF02793. HRM. 1 hit.
PRINTSiPR01129. GIPRECEPTOR.
PR00249. GPCRSECRETIN.
SMARTiView protein in SMART
SM00008. HormR. 1 hit.
SUPFAMiSSF111418. SSF111418. 1 hit.
PROSITEiView protein in PROSITE
PS00649. G_PROTEIN_RECEP_F2_1. 1 hit.
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A1Z2YAL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVCLLLVLF ILTTHTQVSS GKSQKLLQEQ WRIYTNECIQ SFISTPPAAG
60 70 80 90 100
LVCNRTFDQY VCWPDGLPGT TVNVSCPWYL PWYSKVDHGL VYRVCGADGR
110 120 130 140 150
WVHGKNTSEC EQDDPGQKQY GQILSKFRAM YTVGYSLSLA ALTLALGILV
160 170 180 190 200
SFRKLHCMRN NIHMNLFGSF MVRALSILIK DTLLDQMNRA RSGPSHYQST
210 220 230 240 250
RWLDTQTVVG CRSAMVMMQY SVMANNCWLL VEGLYLHSLL VTTVFSERNY
260 270 280 290 300
FCIYLCIGWG APLIFVLPWM TVKYLYENEE CWERNMNMGY WWTIRSPILF
310 320 330 340 350
AYLINFIIFI RIIKILMSKL KAHQMRYTDY KFRLAKSTLT LIPLLGIHAV
360 370 380 390 400
LFTFVIDESV PKESLLRLIR LFYDLLFSSF QGLLVAILYC FVNKEVQSEM
410 420 430 440 450
LKKWKRWKLG KDIDEEYRHT HSQTPHAKSS TAPPAAHDCP DTSSSLESQR
460 470 480 490 500
LVTSLQNGLG RSRGRARLQF TSQTQEGASN CSSLTEDICL EERPLNNEGS

AAVLEETNV
Length:509
Mass (Da):58,361
Last modified:September 27, 2017 - v1
Checksum:i65FB1ADA1DE2A1C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KY465819 mRNA. Translation: ASB51401.1.

Similar proteinsi

Entry informationi

Entry nameiA0A1Z2YAL3_DANRE
AccessioniPrimary (citable) accession number: A0A1Z2YAL3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 27, 2017
Last sequence update: September 27, 2017
Last modified: November 22, 2017
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)